Protein Alignment PH4alphaNE3 and PH4alphaNE1

DIOPT Version :9

• Sequence 1: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 493
• Identity: 144/493 - (29%)
• Similarity: 228/493 - (46%)
• Gaps: 51/493 - (10%)

  Fly    26 DLMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKGREEEYLGNPLHSFPLIRHMYQD 90
            ||:..:..|...|.:....|.....||:.....:.:....|....|.||.||::.:.|::.::.|
  Fly    32 DLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDTENYLTNPVNVYRLMKRLHTD 96

  Fly    91 WRYLEEFMKKPVGEEEIQFLRRKLPELPWQVDTEEASVSIFRIAETYGMMPWDMANGLIDNVRFN 155
            |..:|..::....|......|......|.|.|.|.|::::.|:..||.:....:|.|:::.|::.
  Fly    97 WSLMEGRVQLMAEEMNFNATREYGLSYPSQEDVEGAALALVRLQSTYKLDVAQVAQGILNGVKYG 161

  Fly   156 STLPALDCFEVAKMYFKWGYFKQALQWITISKARMKEEYSGV---------YEVLGMNRQDVALL 211
            |.:...||||:.:..|:...:.....|:..|..|::.:.|..         .:.:.:|:.:..
  Fly   162 SDMSWQDCFELGQQLFEMEDYNNTKVWLRESMERLRRQTSHAPSHLAPTSGPDTVTLNKMEAT-- 224

  Fly   212 QARCLVELDRRDEAHE----VLLDQPDLADNSISLLDQFKANPYEAIDS--SPKLGEG------- 263
             |:.|.:|...|.|.|    ||...|....| ..|.|:..|.| |.||.  .||..:.
  Fly   225 -AKSLFQLGDFDTAFELSQRVLQFDPKRIRN-WHLGDKGTAPP-EDIDDVYLPKHSDSYSLSQEF 286

  Fly   264 --YKRLCRSSFSP-NPSKLHCRYNSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQLITL 325
              |:::||....| ...:|.|||:.....:..|||||:||.||:|::..:||||....|.||..:
  Fly   287 AKYEKVCRGEVHPIVRQELRCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREM 351

  Fly   326 AEPLLKPTEM------------FDDNKNE--ARSSYRTPLGGPLLDSLTQRMRDITGLQIRQGNP 376
            |.|.:..:.:            |..:||.  |..|:.|.:|      :.:.::|.|||.......
  Fly   352 AVPRMHRSTVNPLPGGQLKKSAFRVSKNAWLAYESHPTMVG------MLRDLKDATGLDTTFCEQ 410

  Fly   377 INIIKYGFGAPYTNYYDFFKKRNSESKGFGDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGKV 441
            :.:..||.|..|..::|||:..|......|:|:||.:|||::...||||.||.|::.|..:.|.|
  Fly   411 LQVANYGVGGHYEPHWDFFRDPNHYPAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNV 475

  Fly   442 LFWYNLNGDTHDMEPTTMHAACPVFHGSKWVMTAWIHE 479
            ||||||:... |.:..|.||.|||..||||:...||||
  Fly   476 LFWYNLHRSL-DKDYRTKHAGCPVLKGSKWIGNVWIHE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	29/122 (24%)
		P4Hc	316..478	CDD:214780	59/175 (34%)
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	29/122 (24%)
		P4Hc	341..511	CDD:214780	59/176 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461809
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900