Protein Alignment PH4alphaNE3 and p4ha2

DIOPT Version :10

• Sequence 1: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: XP_005173949.1
• Gene: p4ha2 / 373132
• ZFINID: ZDB-GENE-030827-1
• Length: 542
• Species: Danio rerio
• Alignment Length: 551
• Identity: 150/551 - (27%)
• Similarity: 247/551 - (44%)
• Gaps: 111/551 - (20%)

  Fly     7 STLNWES--RQEFLDTESAKMDLMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKGR 69
            |||::.|  |.|...:.....:|:..:.||:.:|..|.:..::|...::..|.:|.:...::...
Zfish    10 STLSFSSPTRAEIFTSIGQMTNLIFTERELVQSLKEYIQAEEQKLETVRSWANKLDKLTRTSTSD 74

  Fly    70 EEEYLGNPLHSFPLIRHMYQDWRYLEEFMKKPVGEEEIQFLRRKLPELPWQVDTEEASVSIFRIA 134
            .|.:|.:|::::.|::.:..:|..||..:.:...:..|..:.......|.:.|.:.|:.::.|:.
Zfish    75 PEGFLAHPVNAYKLMKRLNTEWSELESLVLQDPSDGFISNMSVHRQYFPDEEDEKGAAKALLRLQ 139

  Fly   135 ETYGMMPWDMANGLI------DNVRFNSTLPALDCFEVAKMYFKWGYFKQALQWITISKARMK-- 191
            :||.:.....:.|.:      ..||:|:.|...|||::.||.:....:..::.|:..|..:|.
Zfish   140 DTYKLDAESFSKGKLPGQRQHSGVRYNALLTVDDCFDMGKMAYNDNDYYHSVLWMQQSLRQMDSG 204

  Fly   192 EE-------------YSGVYEVLGMNRQDVALLQARCLVELDRR----DEAH----------EVL 229
            ||             || ||::..:.|          .:||.||    |.:|          |.|
Zfish   205 EEAKTPKADVLDYLSYS-VYQMGDLPR----------AIELTRRLLAIDPSHQRAGGNLRYFERL 258

  Fly   230 LD---------QPDLADNSISLLDQFKANPYEAIDSSPKLGEGYKRLCRSS----FSPNPSKLHC 281
            |.         ||:.||.....||.:: .|.:.:...    |.|:.|||..    .:...|:|.|
Zfish   259 LSKELQDSGQTQPEPADERPIQLDTYQ-RPKDYLPER----EAYEALCRGEGVKMTTKRQSRLFC 318

  Fly   282 RY-NSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDDNKNEARS 345
            || :...:..|:|.|:|.|:....||||.:.:.|.|::||::..:|.|.|            ||:
Zfish   319 RYRDGNRNPRLLLKPMKEEDEWDSPHIVRFLEALSDEEIQKIKEIATPKL------------ARA 371

  Fly   346 SYRTPLGG--------------------PLLDSLTQRMRDITGLQIRQGNPINIIKYGFGAPYTN 390
            :.|.|..|                    |::..:.||:.|||||.:.....:.:..||.|..|..
Zfish   372 TVRDPKTGVLTVAHYRVSKSAWLEGEDDPVIARVNQRIEDITGLTVDTAELLQVANYGVGGQYEP 436

  Fly   391 YYDFFKKRNSE---SKGFGDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGKVLFWYNL----N 448
            ::||.:|...:   |.|.|:|:||::.|::|...|||||||.....|...:|..:|||||    .
Zfish   437 HFDFSRKDEPDAFKSLGTGNRVATYLNYMSDVEAGGATVFPDFGASVWPRKGTAVFWYNLFRSGE 501

  Fly   449 GDTHDMEPTTMHAACPVFHGSKWVMTAWIHE 479
            ||..     |.||||||..|||||...||||
Zfish   502 GDYR-----TRHAACPVLVGSKWVSNKWIHE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..150	CDD:462433	23/130 (18%)
		P4Hc	316..478	CDD:214780	63/188 (34%)
p4ha2	XP_005173949.1	P4Ha_N	25..156	CDD:462433	23/130 (18%)
		NrfG	177..280	CDD:443378	25/113 (22%)
		P4Hc	353..526	CDD:214780	63/189 (33%)