Protein Alignment PH4alphaNE3 and P4ha2

DIOPT Version :9

• Sequence 1: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_001101745.1
• Gene: P4ha2 / 360526
• RGDID: 1309673
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 144/540 - (26%)
• Similarity: 246/540 - (45%)
• Gaps: 104/540 - (19%)

  Fly     9 LNWESRQEFLDTESAKMDLMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKGREEEY 73
            |:| .:.||..:.....||:..:.:|:.:|..|....:.|.|::|..|.::......:....|.|
  Rat    16 LSW-VQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSAADPEGY 79

  Fly    74 LGNPLHSFPLIRHMYQDWRYLEEFMKKPVGEEEIQFLRRKLPELPWQVDTEEASVSIFRIAETYG 138
            |.:|::::.|::.:..||..|.:.:.:......:..|..:....|...|...|:.::.|:.:||.
  Rat    80 LAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYK 144

  Fly   139 MMPWDMANGLIDNVRFNSTLPALDCFEVAKMYFKWGYFKQALQWI-------------TISKARM 190
            :.|..::.|.:...::.:.|...|||.:.:..:..|.:...:.|:             |::|:.:
  Rat   145 LDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLV 209

  Fly   191 KEEYS-GVYEVLGMNRQDVALLQARCLVELDRR----DEAH----------EVLLDQPDLADNSI 240
            .:..| .|:::..::|          .|||.||    |.:|          |.||::    :...
  Rat   210 LDYLSYAVFQLGDLHR----------AVELTRRLLSLDPSHERAGGNLRYFERLLEE----ERGK 260

  Fly   241 SLLDQFKA------NPYE-AIDSSPKLGEGYKRLCRS---SFSPNPSK-LHCRY-NSTTSAFLIL 293
            ||.:|..|      |.|| .:|..|: .:.|:.|||.   ..:|...| |.||| :......|::
  Rat   261 SLSNQTDAGLASQENLYERPVDYLPE-RDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVPQLLI 324

  Fly   294 APLKMEEISLEPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDDNKNEARSSYRTPLGG----- 353
            ||.|.|:....||||.|:|::.|::|:::..:|:|.|            ||::.|.|..|
  Rat   325 APFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKL------------ARATVRDPKTGVLTVA 377

  Fly   354 ---------------PLLDSLTQRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNSESK 403
                           |::..:.:||:.||||.::....:.:..||.|..|..::||  .|:.|..
  Rat   378 SYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDF--SRSDERD 440

  Fly   404 GF-----GDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGKVLFWYNL----NGDTHDMEPTTM 459
            .|     |:|:|||:.|::|...|||||||.|...:..::|..:|||||    .||..     |.
  Rat   441 AFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYR-----TR 500

  Fly   460 HAACPVFHGSKWVMTAWIHE 479
            ||||||..|.|||...|.||
  Rat   501 HAACPVLVGCKWVSNKWFHE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	26/123 (21%)
		P4Hc	316..478	CDD:214780	61/190 (32%)
P4ha2	NP_001101745.1	P4Ha_N	27..104	CDD:400573	17/76 (22%)
		P4Hc	346..519	CDD:214780	61/191 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920