Protein Alignment PH4alphaNE3 and P4ha3

DIOPT Version :9

• Sequence 1: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: XP_006508007.1
• Gene: P4ha3 / 320452
• MGIID: 2444049
• Length: 551
• Species: Mus musculus
• Alignment Length: 549
• Identity: 146/549 - (26%)
• Similarity: 236/549 - (42%)
• Gaps: 125/549 - (22%)

  Fly    19 DTESAKMDLMQL---DVELIDNLMNYAEKIDEKASQLKR-------LAQELRQPLHSAKGREEEY 73
            ||.||...:.:.   :..|:..|..|....:.:...|.|       |.::|:.|
Mouse    27 DTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHEDLKIP----------- 80

  Fly    74 LGNPLHSFPLIRHMYQDWRYLEEFMKKPVGEEEIQFLR----RKLPELPWQVDTEEASVSIFRIA 134
            :.|||.:|.||:.:..|||.:...::   ..|.|:.|:    :...:||...|.|.|:.::.|:.
Mouse    81 VVNPLLAFTLIKRLQSDWRNVVHSLE---ATENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQ 142

  Fly   135 ETYGMMPWDMANGLIDNVRFNS-----------TLPALDCFEVAK---------MYFKWGYFKQA 179
            :.|.:....:|.|:...|..:|           :|.|.|||:|.|         :.:..|.:..|
Mouse   143 DVYMLNVKGLARGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKPSCGSRSLQVAYDTGDYYHA 207

  Fly   180 LQWITISKARMKEEYSGVYEVLGMNRQDVALLQ---------------ARCLVELDRRDEAHEVL 229
            :.|:..:.:..:..: |.::.     :|.|.|:               ..|.:.|.|     |.|
Mouse   208 IPWLEEAVSLFRRAH-GEWKT-----EDEASLEDALDYLAFACFQVGNVSCALSLSR-----EFL 261

  Fly   230 LDQPD--------------LADNSISLLDQFKANPYEAIDSSPKL--GEGYKRLCRSSFS-PN-- 275
            :..||              ||:|.    .|..|.......:.|.|  .:.|:.||::..| |.
Mouse   262 VYSPDNKRMARNVLKYERLLAENG----HQMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHY 322

  Fly   276 --PSKLHCRYNSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDD 338
              || |:|.|.:.:|.:|:|.|.:.|.:.|.|.|.:|||.:.|::.|::..||||.|:.:.:...
Mouse   323 QIPS-LYCSYETNSSPYLLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELAEPWLQRSVVASG 386

  Fly   339 NK------NEARSSYRTPLGGPLLDSLTQRMRDITGLQIR--QGNPINIIKYGFGAPYTNYYDFF 395
            .|      ..::|::......|:|.:|..|:..:|||.|:  ....:.::.||.|..|..::|..
Mouse   387 EKQLQVEYRISKSAWLKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHA 451

  Fly   396 KKRNS---ESKGFGDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGKVLFWYNL------NGDT 451
            ...:|   ..|. |:|:||||.||:....||||.|...|..||..:...|||:||      :||
Mouse   452 TSPSSPLYRMKS-GNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDGD- 514

  Fly   452 HDMEPTTMHAACPVFHGSKWVMTAWIHEY 480
                  |:||.|||..|.|||...|||||
Mouse   515 ------TLHAGCPVLVGDKWVANKWIHEY 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	29/137 (21%)
		P4Hc	316..478	CDD:214780	58/178 (33%)
P4ha3	XP_006508007.1	P4Ha_N	31..157	CDD:369820	30/139 (22%)
		P4Hc	363..535	CDD:214780	58/179 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740