Protein Alignment PH4alphaNE3 and P4ha1

DIOPT Version :9

• Sequence 1: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_001303300.1
• Gene: P4ha1 / 18451
• MGIID: 97463
• Length: 534
• Species: Mus musculus
• Alignment Length: 498
• Identity: 148/498 - (29%)
• Similarity: 254/498 - (51%)
• Gaps: 52/498 - (10%)

  Fly    26 DLMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKGREEEYLGNPLHSFPLIRHMYQD 90
            ||:..:.:|:.:|.:|.:..::|..|:|:.|::|.:...:|....|.::|:|:::|.|::.:..:
Mouse    30 DLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTE 94

  Fly    91 WRYLEEFMKKPVGEEEIQFLRRKLPELPWQVDTEEASVSIFRIAETYGMMPWDMANGLIDNVRFN 155
            |..||..:.|.:.:..|..|..:....|...|...|:.::||:.:||.:....::.|.:..|:..
Mouse    95 WSELENLILKDMSDGFISNLTIQRQYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHK 159

  Fly   156 STLPALDCFEVAKM-YFKWGYFKQALQWITISKARMKE-EYSGV----------YEVLGMNRQDV 208
            |.|.|.||||:.|: |.:..|:...| |:..:..:::| |.|.|          |.|......|.
Mouse   160 SFLTAEDCFELGKVAYTEADYYHTEL-WMEQALTQLEEGELSTVDKVSVLDYLSYAVYQQGDLDK 223

  Fly   209 ALLQARCLVELDRRDEA-------HEVLLDQPDLADNSIS--LLDQFKANPYE---AIDSSPKLG 261
            |||..:.|:|||...:.       .|.::.:...|:.|.|  ..|| |..|.:   |:|..|: .
Mouse   224 ALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQ-KTAPKKKGIAVDYLPE-R 286

  Fly   262 EGYKRLCRS---SFSPNPSK-LHCRY-NSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQ 321
            :.|:.|||.   ..:|...| |.||| :...:...||||.|.|:...:|.|:.:|||:.|.:|:.
Mouse   287 QKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEI 351

  Fly   322 LITLAEPLLKPTEMFDDNKNE--------ARSSYRTPLGGPLLDSLTQRMRDITGLQIRQGNPIN 378
            :..||:|.|....:.|....:        ::|::.:....|::..:..|::|:|||.:.....:.
Mouse   352 VKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQ 416

  Fly   379 IIKYGFGAPYTNYYDFFKKRNSES---KGFGDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGK 440
            :..||.|..|..::||.:|...::   .|.|:|:||::||::|...|||||||.:...|..::|.
Mouse   417 VANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGT 481

  Fly   441 VLFWYNL----NGDTHDMEPTTMHAACPVFHGSKWVMTAWIHE 479
            .:|||||    .||.     :|.||||||..|:|||...|:||
Mouse   482 AVFWYNLFASGEGDY-----STRHAACPVLVGNKWVSNKWLHE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	30/122 (25%)
		P4Hc	316..478	CDD:214780	57/176 (32%)
P4ha1	NP_001303300.1	P4Ha_N	24..153	CDD:285528	30/122 (25%)
		TPR	205..238		10/32 (31%)
		P4Hc	345..518	CDD:214780	57/177 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920