DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE3 and C14E2.4

DIOPT Version :9

Sequence 1:	NP_651814.1	Gene:	PH4alphaNE3 / 326114	FlyBaseID:	FBgn0051017	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001359861.1	Gene:	C14E2.4 / 182616	WormBaseID:	WBGene00015773	Length:	311	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	57/203 - (28%)
Similarity:	94/203 - (46%)	Gaps:	21/203 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 LKMEEISLEPHIVVYHDILPDKDIQQLITLAEPL-LKPTEMFDDNKNEARSSYR------TPL-- 351
            ::||.:|..|.:|:|.|:...|.:...:.|.:.| :...::..|:...|.|:||      ||.
Worm    81 VRMEILSWSPPLVIYRDVFSKKQVSDYLELLKNLKMNEQKVVRDDGEIAYSTYRQANGTITPAHS 145

  Fly   352 ---GGPLLDSLTQRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNSESKG-----FGDR 408
               ...|:|:.|| :..:...|..:  .|:.:.|..|..|..:.||....|:|...     .|:|
Worm   146 HAEAQSLMDTATQ-LLPVFDFQYTE--QISALSYIKGGHYALHTDFLTFANAEDSNRHFGEMGNR 207

  Fly   409 MATFMFYLNDAPYGGATVFPRLNVKVPAERGKVLFWYNLNGDTHDMEPTTMHAACPVFHGSKWVM 473
            :|||:.....|..||.|:||:|.....|..|....|:|.||:. :.|..::|..||:..|.|.:.
Worm   208 LATFIMVFKKAEKGGGTLFPQLGNVFRANPGDAFLWFNCNGNL-EREAKSLHGGCPIRAGEKIIA 271

  Fly   474 TAWIHEYD 481
            |.||..::
Worm   272 TIWIRIFN 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528
PH4alphaNE3	NP_651814.1	P4Hc	316..478	CDD:214780	49/178 (28%)
C14E2.4	NP_001359861.1	P4Hc	100..276	CDD:214780	49/179 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1438683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780