Protein Alignment PH4alphaNE3 and dpy-18

DIOPT Version :9

• Sequence 1: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_499464.1
• Gene: dpy-18 / 176569
• WormBaseID: WBGene00001077
• Length: 559
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 134/514 - (26%)
• Similarity: 230/514 - (44%)
• Gaps: 71/514 - (13%)

  Fly    18 LDTESAKM-DLMQLDVELIDNLMNYAEKIDEKASQLKRLAQEL--RQPLHSAKGREEEYLGNPLH 79
            |.|..|.| :|::.:..:...|..|....:|:..|||:|::|.  :..:....|.::  :.||::
 Worm    18 LFTSIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKNEISIENGLKD--ITNPIN 80

  Fly    80 SFPLIRHMYQDWRYLEEFMKKPVGEEEIQFLRRKL--PELPWQVDTEEASVSIFRIAETYGMMPW 142
            :|.||:....||:.:|..|........:..:....  ...|...|...|::.:.|:.:||.:...
 Worm    81 AFLLIKRKIFDWKEIESKMNANKAGNVVSSITDDSYGVRYPTADDLSGAAIGLLRLQDTYRLDTK 145

  Fly   143 DMANGLIDNVRFNSTLPALDCFEVAKMYFKWGYFKQALQWITISKARMKEEYSGVYEV------- 200
            |:|:|.|...:.|.|..|.||||:|:..:....|...:.|:..::.|:.:|.....||
 Worm   146 DLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQRRLGDEVEPTVEVEDILEYL 210

  Fly   201 -LGMNRQDVALLQARCLVELDRRDEAH----------EVLLDQPDLADNSI-------------S 241
             ..:.:|:......:...||.:.:..|          |.||:|..:..:.:             |
 Worm   211 AFALYKQNNLKHALKLTEELYKMNPTHPRAKGNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRPDS 275

  Fly   242 LLDQFKANPYEAIDSSPKLGEGYKRLCRSSF---SPNPSKLHCRYNSTTSAFLILAPLKMEEISL 303
            :|...:...|||             |||:..   ..:.|:|:| |......||:.||:|:|....
 Worm   276 VLGNTERTMYEA-------------LCRNEVPVSQKDISRLYC-YYKRDRPFLVYAPIKVEIKRF 326

  Fly   304 EPHIVVYHDILPDKDIQQLITLAEPLLKPTEMFDDNKNE--------ARSSYRTPLGGPLLDSLT 360
            .|..|::.|::.|.::..:..||:|.|....:.|....:        ::|::.....|.:::::.
 Worm   327 NPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLKEWEGDVVETVN 391

  Fly   361 QRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNS---ESKGFGDRMATFMFYLNDAPYG 422
            :|:..:|.|::.....:.|..||.|..|..::|..||..|   ||.|.|:|:||.:||::...:|
 Worm   392 KRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTGNRIATVLFYMSQPSHG 456

  Fly   423 GATVFPRLNVKVPAERGKVLFWYNL--NGDTHDMEPTTMHAACPVFHGSKWVMTAWIHE 479
            |.|||......:...:...||||||  .||.:   |.|.||||||..|.|||...||||
 Worm   457 GGTVFTEAKSTILPTKNDALFWYNLYKQGDGN---PDTRHAACPVLVGIKWVSNKWIHE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	29/128 (23%)
		P4Hc	316..478	CDD:214780	55/174 (32%)
dpy-18	NP_499464.1	P4Ha_N	21..152	CDD:285528	30/132 (23%)
		P4Hc	338..511	CDD:214780	55/175 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920