DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31016 and CG9698

DIOPT Version :9

Sequence 1:	NP_001263119.1	Gene:	CG31016 / 326113	FlyBaseID:	FBgn0051016	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_651806.2	Gene:	CG9698 / 43629	FlyBaseID:	FBgn0039784	Length:	547	Species:	Drosophila melanogaster

Alignment Length:	544	Identity:	152/544 - (27%)
Similarity:	261/544 - (47%)	Gaps:	64/544 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LFAVSFILVLSWI--AEGYRDRQNYVISVEEKMDLLEKDRELIIVLDSYATELNEKIIMLKRIVK 68
            :|:|.|:|....|  ..|.    .:..|:.|...:...::::::.:..:.::..:|:..||..::
  Fly     5 VFSVLFLLFHQAIPSVSGV----EFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLR 65

  Fly    69 EFKQPLEKAKNREEEYLSNPIDSLSLMRQMHEDWEKVEKLLKKPVGQEKIALVEKM--REDLPVE 131
            ||:....:|:.....|..:||:...|.:::..||::||.|:....|::.:..:.|.  ||.:|.:
  Fly    66 EFENERNEAREWGPSYFESPINKYLLNKRLTVDWQRVENLMATSTGEKPLTRLRKFRNRETMPDK 130

  Fly   132 NDLMEANQAMFRILHTYDLEPKDVSAGWIDGVQYGGKMSASDCFTMGTFSFMAGSYQIASKWLSA 196
            .:|..|...:.|:.:.|.|:.||::.|.:|||.||.::::..|..:...:......::|..||..
  Fly   131 KELEGAIDGLLRLQYVYRLKAKDLARGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAHSWLIE 195

  Fly   197 AKD-----------------LLVDQPRKYHEVMGITKADVTLLLARSLIASGNVSIATDMLMRDF 244
            |.|                 |||...::..:..|:......|:..:|.......:..|.:
  Fly   196 ANDRLTGGEKEEQLKPQILALLVQAKKELEDFRGLNDTYQELIGIQSASEEHAKNYETFL----- 255

  Fly   245 MFGEAGSALTVHFLRNKPKPSINL-------ESWESDESFNQLCRSSSRRQMGESKPSRLHCRYN 302
                  :||:...|.|:.||.:..       |.....::::..|  |...::...:...|.|.|.
  Fly   256 ------NALSEKALLNESKPILEHAPIPEEGEPVGEFQAYSLTC--SGHWRLTPKEQRHLRCGYV 312

  Fly   303 TITTPFLKLAPFRMEELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAKVFRVEKGSDEIDPSR 367
            |.|.|||.:||.:.|||..||.::.||:|:..:||:.::.:.:..|.||.:  .......:...|
  Fly   313 TETHPFLWIAPLKAEELFQDPLLVLYHDVIYQSEIDVIRKLTENRLMRATI--TSHNESVVSNVR 375

  Fly   368 SADGAWLP---HQNIDPDDLEVLNRIGRRIEDMTGLNTRSGSKMQFLKYGFGGHFVPHYDYFNSK 429
            ::...::|   |        :||:.|.:|:.|||.||.:.....||..||.|||:..|.|:|...
  Fly   376 TSQFTFIPVTAH--------KVLSTIDQRVADMTNLNMKYAEDHQFANYGIGGHYGQHMDWFYQT 432

  Fly   430 TF-----SLETVGDRIATVLFYLNNVDHGGATVFPKLNLAVPTQKGSALFWHNIDRKSYDYDTRT 489
            ||     |...:|:|||||||||::|..||.|.||:|...:..:|.:|.||||:...... |.||
  Fly   433 TFDAGLVSSPEMGNRIATVLFYLSDVAQGGGTAFPQLRTLLKPKKYAAAFWHNLHASGVG-DVRT 496

  Fly   490 FHGACPLISGTKLVMTRWIYELDQ 513
            .|||||:|:|:|.|..|||.|.||
  Fly   497 QHGACPIIAGSKWVQNRWIRENDQ 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31016	NP_001263119.1	P4Ha_N	31..160	CDD:285528	30/130 (23%)
CG31016	NP_001263119.1	P4Hc	333..508	CDD:214780	66/182 (36%)
CG9698	NP_651806.2	P4Ha_N	28..159	CDD:285528	30/130 (23%)
CG9698	NP_651806.2	P4Hc	345..516	CDD:214780	67/181 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461909
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910