Protein Alignment PH4alphaSG1 and P4ha1

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_742059.2
• Gene: P4ha1 / 64475
• RGDID: 621000
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 184/550 - (33%)
• Similarity: 302/550 - (54%)
• Gaps: 45/550 - (8%)

  Fly     4 LSIILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDE-QQN 67
            :.|:|......|   .::::|.::..|:..|..:|....:|::..:.:.|.:|::.:::|. ...
  Rat     8 MGILLPQCSAHP---GFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTST 69

  Fly    68 DRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLH 132
            ...|.|.:.|:|:|||..:|||..:|  :..:.:......:.:.:||  ::::..|  |..||..
  Rat    70 ATKDPEGFVGHPVNAFKLMKRLNTEW--SELENLILKDMSDGFISNL--TIQRQYF--PNDEDQV 128

  Fly   133 GATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEA 197
            ||.:||.|||:.|.|:|:.::.|.| ||.|:.  :.|:|.|||||||......:|.:...|:.:|
  Rat   129 GAAKALFRLQDTYNLDTNTISKGNL-PGVKHK--SFLTAEDCFELGKVAYTEADYYHTELWMEQA 190

  Fly   198 RKRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEALKNKILYEGQ 262
            ..:|....:.    .|..|.:|::||.|....|:|..|..|..::|:..|:|:.|..|.:.:|..
  Rat   191 LMQLEEGEMS----TVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYI 251

  Fly   263 LARER-------------SFAPRKQ-VELPQIAEKEQKESYKLYTQVCRGE-LHQSPREQRNLRC 312
            :::|:             ...|:|: :.:..:.|:::      |..:|||| :..:||.|:.|.|
  Rat   252 MSKEKDANKSASGDQSDQKTTPKKKGIAVDYLPERQK------YEMLCRGEGIKMTPRRQKRLFC 310

  Fly   313 WLYHQG--VPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENS--T 373
             .||.|  .|.:.|:|.|.|.....|.:...|:::.|:||:.:.:..|..:.|:.|...|..  |
  Rat   311 -RYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLT 374

  Fly   374 TSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQS 438
            |::.|:|::.||....:|.:|:|..|::|:|||...:||.||:.|||:||||||||||...|...
  Rat   375 TAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPD 439

  Fly   439 VFS--WKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCP 501
            .|.  ..|||:.|.|||::||:.||||.||.:..:|.|.||:.:.||||.:|...|:.|:||.||
  Rat   440 AFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACP 504

  Fly   502 VLQGSKWICNEWFHVGAQEFRRPCGLSSDE 531
            ||.|:||:.|:|.|...|||||||.||..|
  Rat   505 VLVGNKWVSNKWLHERGQEFRRPCTLSELE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	36/134 (27%)
		P4Hc	347..515	CDD:214780	77/171 (45%)
P4ha1	NP_742059.2	P4Ha_N	25..112	CDD:400573	19/88 (22%)
		TPR	205..238		11/32 (34%)
		P4Hc	345..518	CDD:214780	77/172 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820