Protein Alignment PH4alphaSG1 and p4ha3

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_021322008.1
• Gene: p4ha3 / 563281
• ZFINID: ZDB-GENE-041010-4
• Length: 616
• Species: Danio rerio
• Alignment Length: 541
• Identity: 173/541 - (31%)
• Similarity: 267/541 - (49%)
• Gaps: 48/541 - (8%)

  Fly     2 FRLSIILSLLCVFPVN-GDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQI--- 62
            |.|.|:|.||.:...: |:.::::..:.:.:..|..:::....|:|...|..|::|||..::
Zfish     5 FTLFIVLYLLNMPDESFGEMFTSMLSVNQAVSAERKLIDHLIIYIEHEAQRLEDIKRFFSRVTSL 69

  Fly    63 -DEQQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNN---LSDSLEKINF 123
             |...|:..|   ...|||.||..:|||..:| .||........|.:..:.:   :..||.|:
Zfish    70 HDGIYNEPSD---PIANPIAAFKLVKRLKSEW-LNVVHSTEAEENIKVLREDYRRMESSLPKL-- 128

  Fly   124 KGPTQEDLHGATRALLRLQNMYQLNTDHLASG----VLHPGE--KNALGTSLSASDCFELGKNLC 182
                 |||.||...|:|||::|.|:.:.|..|    :..|.:  |.::...||..|||.:||...
Zfish   129 -----EDLRGAAHGLMRLQDVYNLHVESLVRGHFQQISDPVDFYKLSVSDMLSGDDCFLVGKVAY 188

  Fly   183 EIKEYSYGSEWLLEARKRLHGKPLGFISP-NVSDVE-ILEHLSSAFNGLGNLKLAYKLNNEILDK 245
            ::::|.:...|..||.:...|...   || |...:| .|:||:.:....||:..|..|:.|:|..
Zfish   189 DLEDYYHSVLWFEEAVRLFRGTEW---SPENEGTLEDALDHLAFSHFKTGNISHALSLSRELLLH 250

  Fly   246 KPDHEEALKNKILYEGQLARERSFAPRKQVELPQIAEKEQKESY----KLYTQVCRGELHQSPR- 305
            .|.:.....|...|| :|..|...|....:.|     |.....|    ..|.|:|:.:..| |:
Zfish   251 DPMNRRVHFNVEKYE-KLLNENLPATSSGLTL-----KRPDGIYLRTRNAYEQLCQTKGSQ-PKH 308

  Fly   306 -EQRNLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQS 369
             |..:|.|..:..|.|...|.|.:.|.:::.|||...|..:..:|...|.::....:.||.|...
Zfish   309 FENPSLFCDYFTNGSPALFLQPIRREIISLQPYVVLFHGFVTQAEAKNIRKYAMPGLRRSVVASG 373

  Fly   370 ENSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTES--AEPLQLVNYGIGGQYEPHFDFV 432
            .|..|:|.|||::.||...|:..:.|:.||:..||||:.:.  ||.||:|||||||.||||||..
Zfish   374 MNQATAEYRISKSAWLKESAHEVVGKLDQRITLVTGLNVQPPYAEYLQVVNYGIGGHYEPHFDHA 438

  Fly   433 EDDGQSVFSWK-GNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTK 496
            ..|...::..| |||:.|.:.||:.|..||:|||.:...:||.|:.:.|.|:|||.:...:..|.
Zfish   439 TSDSSPLYRLKTGNRVATIMIYLSPVQAGGSTAFIYANFSVPVVQNAALFWWNLHKNGQGNVDTL 503

  Fly   497 HAGCPVLQGSKW--ICNEWFH 515
            ||||||:.|:||  ..|:.||
Zfish   504 HAGCPVIVGNKWGMFKNKNFH 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	39/144 (27%)
		P4Hc	347..515	CDD:214780	71/172 (41%)
p4ha3	XP_021322008.1	P4Ha_N	27..157	CDD:311993	39/140 (28%)
		P4Hc	350..519	CDD:214780	70/168 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583389
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950