Protein Alignment PH4alphaSG1 and p4ha3

DIOPT Version :10

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_073779537.1
• Gene: p4ha3 / 563281
• ZFINID: ZDB-GENE-041010-4
• Length: 642
• Species: Danio rerio
• Alignment Length: 567
• Identity: 175/567 - (30%)
• Similarity: 269/567 - (47%)
• Gaps: 74/567 - (13%)

  Fly     2 FRLSIILSLLCVFPVN-GDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQI--- 62
            |.|.|:|.||.:...: |:.::::..:.:.:..|..:::....|:|...|..|::|||..::
Zfish     5 FTLFIVLYLLNMPDESFGEMFTSMLSVNQAVSAERKLIDHLIIYIEHEAQRLEDIKRFFSRVTSL 69

  Fly    63 -DEQQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNN---LSDSLEKINF 123
             |...|:..|   ...|||.||..:|||..:| .||........|.:..:.:   :..||.|:
Zfish    70 HDGIYNEPSD---PIANPIAAFKLVKRLKSEW-LNVVHSTEAEENIKVLREDYRRMESSLPKL-- 128

  Fly   124 KGPTQEDLHGATRALLRLQNMYQLNTDHLASG----VLHPGE--KNALGTSLSASDCFELGKNLC 182
                 |||.||...|:|||::|.|:.:.|..|    :..|.:  |.::...||..|||.:||...
Zfish   129 -----EDLRGAAHGLMRLQDVYNLHVESLVRGHFQQISDPVDFYKLSVSDMLSGDDCFLVGKVAY 188

  Fly   183 EIKEYSYGSEWLLEARKRLHGKPLGFISP-NVSDVE-ILEHLS-SAFNGL--------------- 229
            ::::|.:...|..||.:...|...   || |...:| .|:||: |.|..:
Zfish   189 DLEDYYHSVLWFEEAVRLFRGTEW---SPENEGTLEDALDHLAFSHFKEIKNQLKTWITSPHRRC 250

  Fly   230 ----------GNLKLAYKLNNEILDKKPDHEEALKNKILYEGQLARERSFAPRKQVELPQIAEKE 284
                      ||:..|..|:.|:|...|.:.....|...|| :|..|...|....:.|     |.
Zfish   251 FFQADLNSKTGNISHALSLSRELLLHDPMNRRVHFNVEKYE-KLLNENLPATSSGLTL-----KR 309

  Fly   285 QKESY----KLYTQVCRGELHQSPR--EQRNLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHE 343
            ....|    ..|.|:|:.:..| |:  |..:|.|..:..|.|...|.|.:.|.:::.|||...|.
Zfish   310 PDGIYLRTRNAYEQLCQTKGSQ-PKHFENPSLFCDYFTNGSPALFLQPIRREIISLQPYVVLFHG 373

  Fly   344 VLWDSEIDTIMEHGKGNMERSKVGQSENSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLST 408
            .:..:|...|.::....:.||.|....|..|:|.|||::.||...|:..:.|:.||:..||||:.
Zfish   374 FVTQAEAKNIRKYAMPGLRRSVVASGMNQATAEYRISKSAWLKESAHEVVGKLDQRITLVTGLNV 438

  Fly   409 ES--AEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSWK-GNRLLTALFYLNDVALGGATAFPFLRL 470
            :.  ||.||:|||||||.||||||....|...::..| |||:.|.:.||:.|..||:|||.:...
Zfish   439 QPPYAEYLQVVNYGIGGHYEPHFDHATSDSSPLYRLKTGNRVATIMIYLSPVQAGGSTAFIYANF 503

  Fly   471 AVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKW--ICNEWFH 515
            :||.|:.:.|.|:|||.:...:..|.||||||:.|:||  ..|:.||
Zfish   504 SVPVVQNAALFWWNLHKNGQGNVDTLHAGCPVIVGNKWGMFKNKNFH 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..159	CDD:462433	39/146 (27%)
		P4Hc	347..515	CDD:214780	71/172 (41%)
p4ha3	XP_073779537.1	None