Protein Alignment PH4alphaSG1 and p4ha1a

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_009304776.1
• Gene: p4ha1a / 562774
• ZFINID: ZDB-GENE-040724-91
• Length: 541
• Species: Danio rerio
• Alignment Length: 549
• Identity: 199/549 - (36%)
• Similarity: 310/549 - (56%)
• Gaps: 41/549 - (7%)

  Fly     6 IILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDE-QQNDR 69
            :::|||.....:.|::::|..:..||..|..:|....:|::..:.:.|.:|::.:::|. .....
Zfish    11 LLISLLKSSSAHSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATAV 75

  Fly    70 GDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGA 134
            .|.|.:.|:|:|||..:|||..:|. .|.|.|....: :.:.:||  ::::..|  |..||.:||
Zfish    76 QDPEGFLGHPVNAFKLMKRLNTEWG-EVEDLVLKDMS-DGFISNL--TIQRQYF--PNDEDQNGA 134

  Fly   135 TRALLRLQNMYQLNTDHLASGVLHPGEKNAL--GTSLSASDCFELGKNLCEIKEYSYGSEWLLEA 197
            .:||||||:.|:|:|..::||.| ||....|  .::|:..|||||||......:|.:...|:.:|
Zfish   135 AKALLRLQDTYKLDTQTISSGDL-PGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQA 198

  Fly   198 RKRL-HGKPLGFISPNVSDVEI---LEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEALKNKIL 258
            .|:| .|:.        |.|||   |::||.:....|.|:.|.:....:|..:|:|:.||.|...
Zfish   199 LKQLDEGEE--------SSVEIATALDYLSYSVYQQGELERALEYTKRLLTVEPEHQRALGNLKY 255

  Fly   259 YEGQLARERSFAPRKQVELPQIAEKEQ-----KESY----KLYTQVCRGE-LHQSPREQRNLRCW 313
            ::.|||:::.  ..|:....:.::|||     |:.|    :.|.::|||| |..:||.|::|.|
Zfish   256 FDYQLAKQKK--AEKEQSTKEESKKEQETSDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFC- 317

  Fly   314 LYHQG--VPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENST--T 374
            .|..|  .|:|.:.|.|.|.....|.:...||::.:.||:.|.|..|..:.|:.:.......  |
Zfish   318 RYFNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPITGVLET 382

  Fly   375 SEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSV 439
            :..|||::.||....:|.:.:|.||:||:|||:.::||.||:.|||:||||||||||...|....
Zfish   383 AHYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDA 447

  Fly   440 FS--WKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPV 502
            |.  ..|||:.|.|||::|||.||||.||.:..||.|:||:.:.||||..|...|:.|:||.|||
Zfish   448 FKELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPV 512

  Fly   503 LQGSKWICNEWFHVGAQEFRRPCGLSSDE 531
            |.|:||:.|:|.|...|||||||||...:
Zfish   513 LVGNKWVSNKWIHERGQEFRRPCGLKETD 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	42/134 (31%)
		P4Hc	347..515	CDD:214780	79/171 (46%)
p4ha1a	XP_009304776.1	P4Ha_N	28..157	CDD:285528	42/134 (31%)
		TPR repeat	172..207	CDD:276809	13/34 (38%)
		TPR repeat	212..242	CDD:276809	8/29 (28%)
		Fis1	218..262	CDD:304536	13/43 (30%)
		P4Hc	352..525	CDD:214780	79/172 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750