Protein Alignment PH4alphaSG1 and PH4alphaMP

DIOPT Version :10

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_524594.2
• Gene: PH4alphaMP / 43624
• FlyBaseID: FBgn0026190
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 196/554 - (35%)
• Similarity: 294/554 - (53%)
• Gaps: 47/554 - (8%)

  Fly     6 IILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQID-EQQNDR 69
            ::..:|.|...:|:::|:.|.|.:|.:.|..::.:...|:....|..|.|:..:|.|. |..|..
  Fly     7 VLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAA 71

  Fly    70 GDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGA 134
            ..:::|..||:|||..||||..||:........|||. ..|.:.::...|.::|  |:|:|..|:
  Fly    72 DGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSR-SNYLDTMASLKENLSF--PSQDDFVGS 133

  Fly   135 TRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARK 199
            ..||.|||..|||:...||||:|: |.|  .||::|..|||.||::|..:::|::...||.::.:
  Fly   134 AIALTRLQQTYQLDVAELASGILN-GVK--YGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQ 195

  Fly   200 RLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEAL----------- 253
            .|..:..|..|   :.::.:|.:......:|..:.|..|.|.:|..:||....|
  Fly   196 LLGEQSYGSES---ASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLEARQQLEELI 257

  Fly   254 ----KNKILYEGQLARERSFAPRKQVELPQIAEKEQKESYKLYTQVCRGELHQSPREQRNLRCWL 314
                ||.:|:   |...|.            .:..:...:::|.|||||||...|.:||||||.|
  Fly   258 TDGDKNGLLH---LTARRP------------GDYHESREFRMYEQVCRGELAPLPSKQRNLRCRL 307

  Fly   315 YHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKV---GQSENSTTSE 376
            ....:.|   :|||:|:|::||.|..:|:|:...:.|::.:..:..::||.|   |.:..||.:.
  Fly   308 RKSRLGY---APFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAA 369

  Fly   377 VRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFD-FVEDDGQSVF 440
            .|.|:.....|..|.....:.:.:.|.:||:.:.||.||:.||||||.||||:| |.|:......
  Fly   370 FRTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEG 434

  Fly   441 SWKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQG 505
            ...|||:.|.::||.||..||.||||||.|.|.|.:||||.|||||.|..:|||||||.||||||
  Fly   435 DLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQG 499

  Fly   506 SKWICNEWFHVGAQEFRRPCGLSSDEGKFLHLKD 539
            ||||.|.|.....|:..|||.|...:...||.:|
  Fly   500 SKWIANVWIRERNQDNVRPCDLERGQEISLHYRD 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..159	CDD:462433	47/136 (35%)
		P4Hc	347..515	CDD:214780	79/171 (46%)
PH4alphaMP	NP_524594.2	P4Ha_N	24..158	CDD:462433	47/137 (34%)
		P4Hc	336..509	CDD:214780	79/172 (46%)