Protein Alignment PH4alphaSG1 and PH4alphaSG2

DIOPT Version :10

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_651801.1
• Gene: PH4alphaSG2 / 43623
• FlyBaseID: FBgn0039779
• Length: 527
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 197/551 - (35%)
• Similarity: 298/551 - (54%)
• Gaps: 47/551 - (8%)

  Fly     4 LSIILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQI---DEQ 65
            :.|...::.|...||::||::..::.|..||..::.....|:|..|::.:..:|:::||   .|.
  Fly     9 IGIFQLIIWVGVANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEW 73

  Fly    66 QNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSS---NFETYKNNLSDSLEKINFKGPT 127
            ...:..|::|.|:|::||..|||||.||...:|:|:..::   .|..:...||..|..     |.
  Fly    74 ATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGY-----PD 133

  Fly   128 QEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSE 192
            |.:|.||.:.|.|||.:|.|.|..||.|::  |..| .|:.|...:|:|:|..|.::.||....|
  Fly   134 QSELQGAIKGLARLQKVYNLATSDLADGII--GGLN-YGSDLRWRECYEIGVQLFDLGEYQRSLE 195

  Fly   193 WLLEARKRLHGKPL------GFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEE 251
            ||..|...|...|.      .::|      :|.|:.|.|...|||.|.|.:|.::||:.:|.|..
  Fly   196 WLQVAFILLRNSPREEKDADHYLS------DIREYASMANFELGNPKKAARLLSQILESQPTHSA 254

  Fly   252 ALKNKILYEGQLARERSFAPRKQVELPQIAEKEQKES-YKLYTQVCRGELHQSPREQRNLRCWLY 315
            ....|.|        .|..|.|.|:       |.|.| :..||::|:|......|....|||:|.
  Fly   255 QQTQKYL--------ESRVPGKNVQ-------ETKPSWFSNYTRLCQGRRLPEERSGDPLRCYLD 304

  Fly   316 HQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHG-KGNMERSKV-GQSENSTTSEVR 378
            .:...|:.|:|.::|.:::||.:...|.:|...:|.:|.|.. |..|.||.| |.....|..::|
  Fly   305 GKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGSGGEGTVRDLR 369

  Fly   379 ISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSWK 443
            :|:.|||.| .:|.::.:.:.::.|:|.....||.:|:.|||:|||||||.|:.|.:....|  :
  Fly   370 VSQQTWLDY-KSPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNF--E 431

  Fly   444 GNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKW 508
            |:|:.|::|||:||..||.|.|..|.:.:|||||:|::|:|||.|.|.|.||.||||||:.|||.
  Fly   432 GDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKR 496

  Fly   509 ICNEWFHVGAQEFRRPCGLSSDEGKFLHLKD 539
            |.|.|.|.|.|||||||.|:||..|.|..:|
  Fly   497 IGNIWMHSGYQEFRRPCNLTSDSYKSLAYRD 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..159	CDD:462433	44/141 (31%)
		P4Hc	347..515	CDD:214780	75/169 (44%)
PH4alphaSG2	NP_651801.1	P4Ha_N	28..165	CDD:462433	44/143 (31%)
		CpoB	<178..263	CDD:441335	28/98 (29%)
		P4Hc	335..503	CDD:214780	75/170 (44%)