Protein Alignment PH4alphaSG1 and PH4alphaEFB

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 569
• Identity: 210/569 - (36%)
• Similarity: 311/569 - (54%)
• Gaps: 61/569 - (10%)

  Fly     2 FRLSIILSLLCVF--PVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQEN-LKRFLDQID 63
            :||.::|.:|.:.  |.||:.|:|::|:|.||:.|:.::...:.|: |.|:::.| ||..:|:..
  Fly     5 WRLMLLLGILLLVGGPANGEVYTALAEMEELLETESVLITNLEGYI-RVQEDKLNFLKNKMDEYQ 68

  Fly    64 EQQNDRG-DLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNL------SDSLEKI 121
            .:.:|.. |:..|..|||||::..|||..||:               ...||      :|.|:.|
  Fly    69 REHSDASHDITAYVSNPINAYLLTKRLTTDWR---------------QVENLMEHDVGTDFLQNI 118

  Fly   122 N-----FKGPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNAL--GTSLSASDCFELGK 179
            .     .|.|:.|||:||..||||||:.|||:|..:|.|.|     |.:  .|.:|:.||||||:
  Fly   119 TQYRSLLKFPSDEDLNGAAVALLRLQDTYQLDTSSVARGKL-----NGIQYSTEMSSDDCFELGR 178

  Fly   180 NLCEIKEYSYGSEWLLEARKRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILD 244
            ......:|.:...|:.||..|:..:|... :.:.:..:|||:|:.:....||::.|..:.||:|.
  Fly   179 QSYVNHDYYHTVLWMNEAMARMLEEPTNH-TQSFTKADILEYLAFSTYKEGNIESALTMTNELLQ 242

  Fly   245 KKPDHEEALKNKILYEGQLARERSF-----------APRKQVEL----PQIAEKEQKESYKLYTQ 294
            ..|.||.|..||..||.::|::...           .|:..:.:    |.|.:..::.:|::
  Fly   243 LLPHHERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPKSDLPVAKSDPAIFDMTERRAYEM--- 304

  Fly   295 VCRGELHQSPREQRNLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKG 359
            :|||||..||.:.|:|||......||:.||.|.|:|:::.|||:...|:.::|||||.|....:.
  Fly   305 LCRGELKPSPSDLRSLRCRYVTNRVPFLRLGPLKLEEVHADPYIVIYHDAMYDSEIDLIKRMARP 369

  Fly   360 NMERSKVGQSENST--TSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIG 422
            ...|:.|..|....  |:..|||::.||....:..:..:.||..|:|||..:|||.||:||||||
  Fly   370 RFRRATVQNSVTGALETANYRISKSAWLKTQEDRVIETVVQRTADMTGLDMDSAEELQVVNYGIG 434

  Fly   423 GQYEPHFDFVEDDGQSVFSW--KGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNL 485
            |.|||||||...:.|..|..  .|||:.|.|||::||..||||.|..|..|:.|.||:...|.||
  Fly   435 GHYEPHFDFARKEEQRAFEGLNLGNRIATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNL 499

  Fly   486 HSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPCGLSSDEGKF 534
            |.....|.||:||.||||.|:||:.|:|.|...|||||||.|..|.|:|
  Fly   500 HRDGQGDVRTRHAACPVLTGTKWVSNKWIHERGQEFRRPCDLEEDHGEF 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	50/146 (34%)
		P4Hc	347..515	CDD:214780	79/171 (46%)
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528	50/146 (34%)
		P4Hc	356..529	CDD:214780	79/172 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461964
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900