Protein Alignment PH4alphaSG1 and CG4174

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001034031.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 132/556 - (23%)
• Similarity: 225/556 - (40%)
• Gaps: 140/556 - (25%)

  Fly     6 IILSLLCVFPVNGDYYSAISELE---------RLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQ 61
            ::::....|.|.|:..||....:         .||.::...|.....|.:..::..:.::|.:.|
  Fly     6 VVVTACLGFQVKGEVVSAPESYDFAISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIRRAIRQ 70

  Fly    62 IDE-----QQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKI 121
            .:|     :.:.|        |.|..:..::.|.:||      |.:    |...|.:|  .||:|
  Fly    71 SEELLKSTKTSPR--------NLIYGYKVLRHLHNDW------PQY----FRLLKKDL--GLEQI 115

  Fly   122 NF------KGPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKN 180
            ..      :.||..|...:..|:.|||.:|.|::..:..|.:...:||.  .:.||.:|..||..
  Fly   116 AVSQMLLTQQPTSVDFEESMGAMHRLQTVYNLDSYAMTEGFIDDKDKNI--RNWSADECLMLGLM 178

  Fly   181 LCEIKEYSYGSEWLLEARKRLHGKPLGFISPNVSDVE------ILEHLSSAFNGLGNLKLAYKLN 239
            ...:|:|:....||..|.......    :||.|..::      :||.|..|..|||:...|.|..
  Fly   179 YLFLKDYNQSENWLELALYHYDDN----VSPEVLKIKLWNYPNLLESLVEANKGLGHYFEAKKYA 239

  Fly   240 NEILDKKPDHEEALKNKILYEGQLARERSFAPRKQVELPQIAEKEQ--------KESYKLYTQVC 296
            ||:|...|:|...|                     .:||::...:.        |:.::|..::|
  Fly   240 NELLSINPNHTYML---------------------TQLPKLKHLQSNPAKLTKPKKVFQLQKEIC 283

  Fly   297 RGELHQSPREQRN---LRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTI----- 353
                  |.|.:|.   |.| .|....|:.:|:|.|:|:|::.||::..:..|...:|:.:
  Fly   284 ------SKRYRRKSGVLVC-RYVDWTPFLKLAPLKMEELSMKPYISIFYGFLGQKDIEVLKNVSR 341

  Fly   354 -----MEHGKGNMERSKVGQSENSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEP 413
                 :||..||.. .|:|....|....||                |:.:.:..:||...:..:.
  Fly   342 PKLQRIEHLSGNCS-CKIGNLSTSLHDVVR----------------KVNELILGITGFPLKGNQM 389

  Fly   414 LQLVNYGIGGQYEPHFDFVEDDGQSVFSWKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGS 478
            |:::||||.|.|.|....:.:        |.|    |..:|::...||...||...|.|.|.|||
  Fly   390 LEVINYGIAGNYNPEEPKIHN--------KAN----AFIFLSNAGKGGEIVFPSRHLKVRPRKGS 442

  Fly   479 LLIWYNLHSST--HKDFRTKHAGCPVLQGSKWICNE 512
            :|:|.||..|.  |:        ||:|:|:.|:.|:
  Fly   443 MLVWENLKKSLIYHQ--------CPILKGNMWVANK 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	31/153 (20%)
		P4Hc	347..515	CDD:214780	47/178 (26%)
CG4174	NP_001034031.2	P4Ha_N	33..157	CDD:285528	30/143 (21%)
		TPR repeat	169..197	CDD:276809	9/27 (33%)
		TPR repeat	202..245	CDD:276809	15/46 (33%)
		2OG-FeII_Oxy	<362..470	CDD:304390	39/143 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461951
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990