Protein Alignment PH4alphaSG1 and PH4alphaNE3

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 136/512 - (26%)
• Similarity: 238/512 - (46%)
• Gaps: 67/512 - (13%)

  Fly    19 DYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDEQ-QNDRGDLEEYFGNPINA 82
            |..||..:|.: ||||  :::....|.|:..::...|||...::.:. .:.:|..|||.|||:::
  Fly    19 DTESAKMDLMQ-LDVE--LIDNLMNYAEKIDEKASQLKRLAQELRQPLHSAKGREEEYLGNPLHS 80

  Fly    83 FITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINF------KGPTQEDLHGATRALLRL 141
            |..|:.:..||::..          |..|..:.:  |:|.|      :.|.|.|...|:.::.|:
  Fly    81 FPLIRHMYQDWRYLE----------EFMKKPVGE--EEIQFLRRKLPELPWQVDTEEASVSIFRI 133

  Fly   142 QNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARKRLHGKPL 206
            ...|.:....:|:|::   :.....::|.|.||||:.|...:...:....:|:..::.|:..:..
  Fly   134 AETYGMMPWDMANGLI---DNVRFNSTLPALDCFEVAKMYFKWGYFKQALQWITISKARMKEEYS 195

  Fly   207 G---FISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPD-HEEALKNKILYEGQLARER 267
            |   .:..|..||.:|:              |..|..  ||::.: ||..|....|.:..::...
  Fly   196 GVYEVLGMNRQDVALLQ--------------ARCLVE--LDRRDEAHEVLLDQPDLADNSISLLD 244

  Fly   268 SFA--PRKQVE-LPQIAEKEQKESYKLYTQVCRGELHQSPREQRNLRCWLYHQGVPYYRLSPFKI 329
            .|.  |.:.:: .|::.|.        |.::||.....:|.:   |.|........:..|:|.|:
  Fly   245 QFKANPYEAIDSSPKLGEG--------YKRLCRSSFSPNPSK---LHCRYNSTTSAFLILAPLKM 298

  Fly   330 EQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENSTTSEVRISRNTWLWYDANPWLS 394
            |:::::|::...|::|.|.:|..::...:..:   |..:..:...:|.|.|..|.|   ..|.|.
  Fly   299 EEISLEPHIVVYHDILPDKDIQQLITLAEPLL---KPTEMFDDNKNEARSSYRTPL---GGPLLD 357

  Fly   395 KIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSWKGNRLLTALFYLNDVAL 459
            .:.||:.|:|||......|:.::.||.|..|..::||.:........: |:|:.|.:|||||...
  Fly   358 SLTQRMRDITGLQIRQGNPINIIKYGFGAPYTNYYDFFKKRNSESKGF-GDRMATFMFYLNDAPY 421

  Fly   460 GGATAFPFLRLAVPPVKGSLLIWYNLHSSTH-KDFRTKHAGCPVLQGSKWICNEWFH 515
            ||||.||.|.:.||..:|.:|.||||:..|| .:..|.||.|||..||||:...|.|
  Fly   422 GGATVFPRLNVKVPAERGKVLFWYNLNGDTHDMEPTTMHAACPVFHGSKWVMTAWIH 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	35/140 (25%)
		P4Hc	347..515	CDD:214780	59/168 (35%)
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	34/138 (25%)
		P4Hc	316..478	CDD:214780	59/168 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461963
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900