Protein Alignment PH4alphaSG1 and P4ha3

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_006508007.1
• Gene: P4ha3 / 320452
• MGIID: 2444049
• Length: 551
• Species: Mus musculus
• Alignment Length: 563
• Identity: 188/563 - (33%)
• Similarity: 274/563 - (48%)
• Gaps: 57/563 - (10%)

  Fly     8 LSLLCVFPVNG---------DYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQID 63
            |:||.:..:.|         |.:||::.:.|.|..|..::.....||...:....:|.||.|::.
Mouse     7 LALLALLALGGDPAAATGREDTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVL 71

  Fly    64 EQQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQ 128
            ....   ||:....||:.||..||||..||: ||...:..:.|...    |.|..||:....|..
Mouse    72 SLHE---DLKIPVVNPLLAFTLIKRLQSDWR-NVVHSLEATENIRA----LKDGYEKVEQDLPAF 128

  Fly   129 EDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGT------------SLSASDCFELGKNL 181
            |||.||.|||:|||::|.||...||.||.    :...|:            ||:|.|||::||..
Mouse   129 EDLEGAARALMRLQDVYMLNVKGLARGVF----QRVTGSSITDLYSPRQLFSLTADDCFQVGKPS 189

  Fly   182 C---------EIKEYSYGSEWLLEA---RKRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKL 234
            |         :..:|.:...||.||   .:|.||:.......::.|.  |::|:.|...:||:..
Mouse   190 CGSRSLQVAYDTGDYYHAIPWLEEAVSLFRRAHGEWKTEDEASLEDA--LDYLAFACFQVGNVSC 252

  Fly   235 AYKLNNEILDKKPDHEEALKNKILYEGQLARE-RSFAPRKQVELPQIAEKEQKESYKLYTQVCRG 298
            |..|:.|.|...||::...:|.:.||..||.. ...|....::.|.:...:.:::|:...|.
Mouse   253 ALSLSREFLVYSPDNKRMARNVLKYERLLAENGHQMAAETAIQRPNVPHLQTRDTYEGLCQT--- 314

  Fly   299 ELHQSPREQR--NLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNM 361
             |...|...:  :|.|.......||..|.|.:.|.:::.|.:|..|:.:.|.|...|.|..:..:
Mouse   315 -LGSQPTHYQIPSLYCSYETNSSPYLLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELAEPWL 378

  Fly   362 ERSKVGQSENSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTES--AEPLQLVNYGIGGQ 424
            :||.|...|.....|.|||::.||....:|.|..:..|:..:|||..:.  ||.||:|||||||.
Mouse   379 QRSVVASGEKQLQVEYRISKSAWLKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGH 443

  Fly   425 YEPHFDFVEDDGQSVFSWK-GNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSS 488
            ||||||........::..| |||:.|.:.||:.|..||||||.:...:||.||.:.|.|:|||.|
Mouse   444 YEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRS 508

  Fly   489 THKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPCGLSSDE 531
            ...|..|.|||||||.|.||:.|:|.|...|||||||..:.::
Mouse   509 GEGDGDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSTNPED 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	47/133 (35%)
		P4Hc	347..515	CDD:214780	75/170 (44%)
P4ha3	XP_006508007.1	P4Ha_N	31..157	CDD:369820	47/133 (35%)
		P4Hc	363..535	CDD:214780	75/171 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839333
Domainoid	1	1.000	66	1.000	Domainoid score	I9954
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4458
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790