DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaSG1 and phy-3

DIOPT Version :9

Sequence 1:	NP_733376.1	Gene:	PH4alphaSG1 / 326112	FlyBaseID:	FBgn0051014	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_507251.2	Gene:	phy-3 / 188624	WormBaseID:	WBGene00004026	Length:	318	Species:	Caenorhabditis elegans

Alignment Length:	263	Identity:	57/263 - (21%)
Similarity:	102/263 - (38%)	Gaps:	53/263 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 QVCRGELHQSPREQRNLRCWLYHQGVPYYRLSPFKIEQLNVDP----------------YVAYVH 342
            ::|..|...:..::.:..|..|     .|.:.|..:|.::..|                ::.::.
Worm    55 ELCDDETKDTKWQKNDSICITY-----VYNMLPVDMEIISWAPTLVIYRNLMSPRQTASFLNFIE 114

  Fly   343 ----EVLWDSEIDTIME--HGKGNMERSKVGQSENSTTSEVRISRNTWLWYDANPWLSKIKQRLE 401
                |:...|:..|.:|  |.:.|  .|.:...:::.|.|:::                  |..:
Worm   115 QRDLEIQKTSDFGTSIETTHRRAN--GSFIPPEDSNVTVEIKM------------------QAQK 159

  Fly   402 DVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSW----KGNRLLTALFYLNDVALGGA 462
            .:.||:...||....::|..||.|..|:|:::...:..:.|    .|||:.|.:|.|.....||.
Worm   160 RIPGLNLTVAEHFSALSYLPGGHYAVHYDYLDYRSKQDYDWWMNKTGNRIGTLIFVLKPAEKGGG 224

  Fly   463 TAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEF--RRPC 525
            |.||.:...|....|....|:|..:...|:..:.|.|||:.:|.|.|...|.....|..  ..|.
Worm   225 TVFPSIGSTVRANAGDAFFWFNAQADEEKEMLSNHGGCPIYEGRKVIATIWIRAYNQRILPMAPA 289

  Fly   526 GLS 528
            |.|
Worm   290 GSS 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528
PH4alphaSG1	NP_733376.1	P4Hc	347..515	CDD:214780	44/173 (25%)
phy-3	NP_507251.2	P4Hc	102..277	CDD:214780	45/194 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770