Protein Alignment PH4alphaSG1 and phy-2

DIOPT Version :9

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_502317.1
• Gene: phy-2 / 178170
• WormBaseID: WBGene00004025
• Length: 539
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 184/540 - (34%)
• Similarity: 289/540 - (53%)
• Gaps: 33/540 - (6%)

  Fly     5 SIILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFL-DQIDEQQND 68
            :::|..|.....:.|.::||::|:.:|..|..:....|:|:|..:...::|:|:. :.:....:.
 Worm     3 AVLLVCLLAGLAHADLFTAIADLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEYVHRNAHA 67

  Fly    69 RGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHG 133
            .....|:..|||||::.||||..:||  ..:.:..::...|:..|::|:..:...|.|.:|||.|
 Worm    68 ESVGPEFVTNPINAYLLIKRLTTEWK--KVENIMLNNKASTFLKNITDNRVRSEVKFPGEEDLSG 130

  Fly   134 ATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEAR 198
            |..||||||:.|.|:|..|::|:: .|||  :...||..|.||:|::....|:|.:...|:..|.
 Worm   131 AATALLRLQDTYSLDTLDLSNGII-GGEK--VSNKLSGHDTFEVGRSAYNQKDYYHCLMWMQVAL 192

  Fly   199 KRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEALKNKILYEGQL 263
            .::..:.    .|.:.:.||||:|:.:....||::.|..|...:....|:|..|..|...||..|
 Worm   193 VKIENEN----PPTIEEWEILEYLAYSLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDML 253

  Fly   264 ARERSFAP-----RKQVELPQIAEKEQKESYKLYTQVCRGELHQ-SPREQRNLRCWLYHQGVPYY 322
            ..:.....     .|:||...|.|::      .|..:||||:.. .|:.:..|||:| .:..|:.
 Worm   254 QGKDMVGDLPPIVNKRVEYDGIVERD------AYEALCRGEIPPVEPKWKNKLRCYL-KRDKPFL 311

  Fly   323 RLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMER-----SKVGQSENSTTSEVRISRN 382
            :|:|.|:|.|..||.......|:.||||:.|.|.....::|     ||.|:.|::|   .|||::
 Worm   312 KLAPIKVEILRFDPLAVLFKNVIHDSEIEVIKELASPKLKRATVQNSKTGELEHAT---YRISKS 373

  Fly   383 TWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSW--KGN 445
            .||..|.:|.:.::.:|:||.|.|:..::|.||:.|||:||.|:|||||...:.::.|..  .||
 Worm   374 AWLKGDLDPVIDRVNRRIEDFTNLNQATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGN 438

  Fly   446 RLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKWIC 510
            |:.|.|||::....||||.|..|..||.|.|...|.||||......|.||:||.||||.|.||:.
 Worm   439 RIATVLFYMSQPERGGATVFNHLGTAVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVS 503

  Fly   511 NEWFHVGAQEFRRPCGLSSD 530
            |:|.|...|||.|||||..:
 Worm   504 NKWIHEKGQEFTRPCGLEEE 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..157	CDD:285528	43/134 (32%)
		P4Hc	347..515	CDD:214780	75/174 (43%)
phy-2	NP_502317.1	P4Ha_N	21..154	CDD:285528	43/134 (32%)
		TPR_16	169..240	CDD:290168	18/74 (24%)
		P4Hc	335..508	CDD:214780	75/175 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820