Protein Alignment PH4alphaSG1 and LOC100492280

DIOPT Version :10

• Sequence 1: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_031761347.1
• Gene: LOC100492280 / 100492280
• XenbaseID: XB-GENE-29081095
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 572
• Identity: 193/572 - (33%)
• Similarity: 300/572 - (52%)
• Gaps: 64/572 - (11%)

  Fly     3 RLSIILSLLCVFP-VNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDE-Q 65
            ::.::|.||.:|. .:.|::::|..:..||:.|..:|....:|::..:|:...:|::.|::|. .
 Frog     2 KIHLVLPLLGLFSCAHADFFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLT 66

  Fly    66 QNDRGDLEEYFGNPINAFITIKRLVHDW-KFN--VFDPVFDSSNFETYKNNLSDSLEKINFKGPT 127
            .....|.|.:.|:|:|||..:|||..:| |..  :...:.|.     :.:||  ::::..|  |.
 Frog    67 DTATKDPEGFLGHPVNAFKLMKRLNTEWVKLENLILKDISDG-----FISNL--TIQRQYF--PN 122

  Fly   128 QEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSE 192
            .||..||.:||||||:.|.|:||.::.|.| ||.|:.  |||:|.|||:|||......:|.:...
 Frog   123 DEDQTGAAKALLRLQDTYNLDTDTISKGNL-PGVKHK--TSLTAEDCFDLGKTAYTDADYYHTEL 184

  Fly   193 WLLEARKRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEALKNKI 257
            |:.:|..:|....    ..::..|.:|::||.|....|:|..|..|...:|:..|:|:....|..
 Frog   185 WMEQALSQLDAGE----ESSLDKVMVLDYLSYAVYQQGDLDKALTLTKLLLELDPEHQRGNGNLR 245

  Fly   258 LYEGQLARE---RSFAPRKQVEL------PQIAEKEQKESYKLYTQVCRGE-LHQSPREQRNLRC 312
            .:|..:::|   .|.:|.:..||      |    |:.....:.|.::|||| :..:.|.|:.|.|
 Frog   246 YFEYIMSKESNKSSSSPSEGAELGTRKGRP----KDHLPERQKYEKLCRGEGVKMTSRRQKRLFC 306

  Fly   313 WLYHQG--VPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVG-------- 367
             .|..|  .|...|||.|.|.....|.:...|:::.|.||..:.|..|..:.|:.:.
 Frog   307 -RYFDGNKDPLLILSPTKQEDEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLE 370

  Fly   368 ----------------QSENSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQL 416
                            |:...||::.|:|::.||....:|.::::.:|:|.||||...:||.||:
 Frog   371 TAQYRISKRRATVHDPQTGKLTTAQYRVSKSAWLSAYEDPVVARLNRRIEGVTGLDMSTAEELQV 435

  Fly   417 VNYGIGGQYEPHFDFVEDDGQSVFS--WKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSL 479
            .|||:||||||||||...|....|.  ..|||:.|.|||::||..||||.||.:..||.|.||:.
 Frog   436 ANYGMGGQYEPHFDFARKDEPDAFKELGTGNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTA 500

  Fly   480 LIWYNLHSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPCGLSSDE 531
            :.||||..|...|:.|:||.||||.|:||:.|:|.|...|||||||.||..|
 Frog   501 VFWYNLFESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFRRPCNLSELE 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaSG1	NP_733376.1	P4Ha_N	23..159	CDD:462433	43/139 (31%)
		P4Hc	347..515	CDD:214780	77/193 (40%)
LOC100492280	XP_031761347.1	P4Ha_N	23..154	CDD:462433	43/140 (31%)
		P4Hc	341..536	CDD:214780	77/194 (40%)