DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31013 and p4htmb

DIOPT Version :9

Sequence 1:	NP_733394.3	Gene:	CG31013 / 326111	FlyBaseID:	FBgn0051013	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	XP_001340234.2	Gene:	p4htmb / 799930	ZFINID:	ZDB-GENE-110131-7	Length:	510	Species:	Danio rerio

Alignment Length:	387	Identity:	93/387 - (24%)
Similarity:	142/387 - (36%)	Gaps:	117/387 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 PRHLPIKEVDALRL-------LAEAQIKDQNYSEALPLLHNCLKLQPHD--ARVLRLWK------ 258
            ||::.:..::.:|:       |...::.:.......|||.........:  |.|:||.:
Zfish   119 PRNMFLPRIEGIRVGHVQKVSLVSGKVHEMKTLSLKPLLFEIPDFLSEEECAVVVRLAQLKGLME 183

  Fly   259 ------KTTDFIENQPDQSPTENKKRNVPIANAFKLSCNGPLE----------------SSTRLH 301
                  :..:.::.|.:.||.|       |.|...|:.:|.|:                :|..|.
Zfish   184 SQVMVPEGQEELDQQLNLSPEE-------IFNFLDLNQDGQLQPHEILTHSRVRDGIWLTSENLK 241

  Fly   302 CFYNFTTTPFLRLAPLKTEQIGLDPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKERAVPKKN 366
            ..|:          .||.:..|        :.:||..|...|...|.|     :...:|.|.:..
Zfish   242 EIYD----------GLKADLDG--------NGLLSLEEFGRLRSDAFQ-----RFLLQRGVERSQ 283

  Fly   367 RGRTAKGFWLKKES------NELTKRITRRIMDMTGFDLAD-SEGFQVINYGIGGHYFLHMD--- 421
            ..|.::..||.:..      .:|.||:|  ::......|.: ||..||:.|..||||..|.|
Zfish   284 LVRNSRHTWLYQGQGAHQVLQDLRKRVT--LLTRLPSSLVELSEPLQVVRYEQGGHYHAHHDSGP 346

  Fly   422 YFDFASSNHT----DTRSRYSIDLGDRIATVLFYLTDVEQGGATVF---------------GDV- 466
            .:...:..||    :|.|.:....  |..||||||.:|::||.|.|               .||
Zfish   347 VYPETACTHTRLAANTTSPFQTSC--RYITVLFYLNNVQEGGETTFPVADNRTYEEASLIQNDVD 409

  Fly   467 -----------GYYVSPQAGTAIFWYNLDTDGNG-----DPRTRHAACPVIVGSKWVMTEWI 512
                       ...|.|..|||:||||..:||.|     |..:.|..|.|..|:|||...||
Zfish   410 LLDTRKHCDKGNLRVKPVKGTAVFWYNYLSDGRGWVGEQDEYSLHGGCVVTQGTKWVANNWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31013	NP_733394.3	P4Ha_N	31..160	CDD:285528
		TPR_11	178..248	CDD:290150	7/45 (16%)
		TPR repeat	211..246	CDD:276809	5/41 (12%)
		P4Hc	336..513	CDD:214780	66/223 (30%)
p4htmb	XP_001340234.2	EF-hand_7	204..262	CDD:290234	14/82 (17%)
		EFh	204..262	CDD:298682	14/82 (17%)
		P4Hc	285..471	CDD:214780	57/189 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583459
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740