Protein Alignment CG31013 and P4HTM

DIOPT Version :10

• Sequence 1: NP_733394.3
• Gene: CG31013 / 326111
• FlyBaseID: FBgn0051013
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_808807.2
• Gene: P4HTM / 54681
• HGNCID: 28858
• Length: 563
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 74/312 - (23%)
• Similarity: 104/312 - (33%)
• Gaps: 119/312 - (38%)

  Fly   334 VLSAREISMLIGKAAQNMKNTKIHKERAVPKKNRG---RTAKGFWL--KKESNELTKRITRRIMD 393
            |||.:|.|        ||.....||.....|....   |.:...||  .:.::.:.:.|.:|::.
Human   243 VLSLQEFS--------NMDLRDFHKYMRSHKAESSELVRNSHHTWLYQGEGAHHIMRAIRQRVLR 299

  Fly   394 MTGF--DLAD-SEGFQVINYGIGGHYFLHMD---YFDFASSNHTDTRSRYSIDL----------- 441
            :|..  ::.: ||..||:.||.||||..|:|   .:.....:||...:..|:..
Human   300 LTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRQVSPNW 364

  Fly   442 ----------------------------GDR------------------------IATVLFYLTD 454
                                        ||.                        ..||||||.:
Human   365 GLPSILRPGTPMTQAQPCTVGVPLGMGPGDHWVIPVSPWEHPQLGTCSVPPLPYSYMTVLFYLNN 429

  Fly   455 VEQGGATVF---------------GDV------------GYYVSPQAGTAIFWYNLDTDGNG--- 489
            |..||.|||               .||            ...|.||.|||:||||...||.|
Human   430 VTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVG 494

  Fly   490 --DPRTRHAACPVIVGSKWVMTEWI-----REKRQIFIRPCLPKAKGTSTKS 534
              |..:.|..|.|..|:||:...||     |.::.:|.:.....|:...|.|
Human   495 DVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGTDS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31013	NP_733394.3	P4Ha_N	31..162	CDD:462433
		NrfG	<181..256	CDD:443378
		TPR repeat	211..246	CDD:276809
		P4Hc	336..513	CDD:214780	67/287 (23%)
P4HTM	NP_808807.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..111
		EF-hand_7	192..252	CDD:463900	5/16 (31%)
		P4Hc	246..519	CDD:214780	64/280 (23%)