Protein Alignment CG31013 and P4ha2

DIOPT Version :10

• Sequence 1: NP_733394.3
• Gene: CG31013 / 326111
• FlyBaseID: FBgn0051013
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001101745.1
• Gene: P4ha2 / 360526
• RGDID: 1309673
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 162/539 - (30%)
• Similarity: 247/539 - (45%)
• Gaps: 81/539 - (15%)

  Fly    31 SLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRRNAISYLSNPLNGFSII 95
            |:..|..|:..||.|:.:|:.|..|.|.||..|:|....:.|...|...:...||::|:|.:.::
  Rat    26 SIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSAADPEGYLAHPVNAYKLV 90

  Fly    96 RRLHQDWINWRKYMEQPVGIWQLKAFYSWKDELPTERDLWDACEGIARIQSTYDLKVGDFINGNI 160
            :||:.||......:.|......:......:...||:.|...|...:.|:|.||.|.......|.:
  Rat    91 KRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDMISRGEL 155

  Fly   161 NGKQYNDSMSTADILSVGAYLFMKNRPSDAIQWLQEVPQRLQEELLIQPRHLPIKEVDA------ 219
            .|.:|...:|..|...:|...:.:......:.|:::|                :|::||
  Rat   156 PGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQV----------------LKQLDAGEEATV 204

  Fly   220 -----LRLLAEAQIKDQNYSEALPLLHNCLKLQPHDARV---LRLWKKTTD-----FIENQPD-- 269
                 |..|:.|..:..:...|:.|....|.|.|...|.   ||.:::..:     .:.||.|
  Rat   205 TKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAG 269

  Fly   270 ----QSPTENKKRNVPIANAFKLSCNGPLESST-----RLHCFYNF-TTTPFLRLAPLKTEQIGL 324
                ::..|.....:|..:.::..|.|.....|     ||.|.|:. ...|.|.:||.|.|....
  Rat   270 LASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVPQLLIAPFKEEDEWD 334

  Fly   325 DPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKERAVPKKNRG---------------RTAKGF 374
            .|::|.|::|:|..||..:              ||.|.||..|.               |.:|..
  Rat   335 SPHIVRYYDVMSDEEIERI--------------KEIAKPKLARATVRDPKTGVLTVASYRVSKSS 385

  Fly   375 WLKKESNELTKRITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSRYSI 439
            ||:::.:.:..|:.||:..:||..:..:|..||.|||:||.|..|   |||:.|:..|...|  :
  Rat   386 WLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPH---FDFSRSDERDAFKR--L 445

  Fly   440 DLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNGDPRTRHAACPVIVGS 504
            ..|:|:||.|.|::|||.||||||.|:|..:.|:.|||:|||||...|.||.|||||||||:||.
  Rat   446 GTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGC 510

  Fly   505 KWVMTEWIREKRQIFIRPC 523
            |||..:|..|:.|.|:|||
  Rat   511 KWVSNKWFHERGQEFLRPC 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31013	NP_733394.3	P4Ha_N	31..162	CDD:462433	35/130 (27%)
		NrfG	<181..256	CDD:443378	15/88 (17%)
		TPR repeat	211..246	CDD:276809	9/45 (20%)
		P4Hc	336..513	CDD:214780	78/191 (41%)
P4ha2	NP_001101745.1	P4Ha_N	26..157	CDD:462433	35/130 (27%)
		P4Hc	346..519	CDD:214780	78/191 (41%)