Protein Alignment CG31013 and P4ha2

DIOPT Version :10

• Sequence 1: NP_733394.3
• Gene: CG31013 / 326111
• FlyBaseID: FBgn0051013
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_006532515.1
• Gene: P4ha2 / 18452
• MGIID: 894286
• Length: 557
• Species: Mus musculus
• Alignment Length: 558
• Identity: 159/558 - (28%)
• Similarity: 249/558 - (44%)
• Gaps: 99/558 - (17%)

  Fly    31 SLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRRNAISYLSNPLNGFSII 95
            |:..|..|:..||.|:.:|:.|....|.||..|:|....:.|...:...:...||::|:|.:.::
Mouse    28 SIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAYKLV 92

  Fly    96 RRLHQDWINWRKYMEQPVGIWQLKAFYSWKDELPTERDLWDACEGIARIQSTYDLKVGDFINGNI 160
            :||:.||......:.|......:......:...||:.|...|...:.|:|.||.|.......|.:
Mouse    93 KRLNTDWPALGDLVLQDASAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGEL 157

  Fly   161 NGKQYNDSMSTADILSVGAYLFMKNRPSDAIQWLQEVPQRLQEELLIQPRHLPIKEVDA------ 219
            .|.:|...:|..|...:|...:.:......:.|:::|                :|::||
Mouse   158 PGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQV----------------LKQLDAGEEATV 206

  Fly   220 -----LRLLAEAQIKDQNYSEALPLLHNCLKLQPHDARV---LRLWKKTTD-----FIENQPD-- 269
                 |..|:.|..:..:...|:.|....|.|.|...|.   ||.:::..:     .:.||.|
Mouse   207 TKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAG 271

  Fly   270 --------QSPTENKKRNVPIANAFKLSCNGPLESST-----RLHCFYNF-TTTPFLRLAPLKTE 320
                    :.||:    .:|..:.::..|.|.....|     :|.|.|:. ...|.|.:||.|.|
Mouse   272 LATQENLYERPTD----YLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEE 332

  Fly   321 QIGLDPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKERAVPKKNRG---------------RT 370
            .....|::|.|::|:|..||..:              ||.|.||..|.               |.
Mouse   333 DEWDSPHIVRYYDVMSDEEIERI--------------KEIAKPKLARATVRDPKTGVLTVASYRV 383

  Fly   371 AKGFWLKKESNELTKRITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDY----FDFASS--- 428
            :|..||:::.:.:..|:.||:..:||..:..:|..||.|||:||.|..|.|:    ||....
Mouse   384 SKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTEG 448

  Fly   429 -------NHTDTRSRYS-IDLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDT 485
                   |::|.:..:. :..|:|:||.|.|::|||.||||||.|:|..:.|:.|||:|||||..
Mouse   449 NRLATFLNYSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLR 513

  Fly   486 DGNGDPRTRHAACPVIVGSKWVMTEWIREKRQIFIRPC 523
            .|.||.|||||||||:||.|||..:|..|:.|.|:|||
Mouse   514 SGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31013	NP_733394.3	P4Ha_N	31..162	CDD:462433	33/130 (25%)
		NrfG	<181..256	CDD:443378	15/88 (17%)
		TPR repeat	211..246	CDD:276809	9/45 (20%)
		P4Hc	336..513	CDD:214780	77/206 (37%)
P4ha2	XP_006532515.1	P4Ha_N	28..159	CDD:462433	33/130 (25%)
		P4Hc	348..541	CDD:214780	77/206 (37%)