DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31013 and p4ha1

DIOPT Version :9

Sequence 1:	NP_733394.3	Gene:	CG31013 / 326111	FlyBaseID:	FBgn0051013	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	XP_031761963.1	Gene:	p4ha1 / 100490484	XenbaseID:	XB-GENE-987760	Length:	526	Species:	Xenopus tropicalis

Alignment Length:	529	Identity:	161/529 - (30%)
Similarity:	248/529 - (46%)	Gaps:	67/529 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRRNAISYLSNPLNGFSII 95
            |:..|:.||..||.|:.:|::|..|.||||..|:.....:....:...::...||.:|:|.|.::
Frog    23 SIGHMIDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGYLGHPVNAFKLM 87

  Fly    96 RRLHQDWINWRKYMEQPVGIWQLKAFYSWKDELPTERDLWDACEGIARIQSTYDLKVGDFINGNI 160
            :||:.:|:.....:.:.:....:......:...|.:.|...|.:.:.|:|.||:|.......||:
Frog    88 KRLNTEWVKLENLILKDISDGFISNLTIQRQYFPNDEDQTGAAKALLRLQDTYNLDTDTISKGNL 152

  Fly   161 NGKQYNDSMSTADILSVGAYLFMKNRPSDAIQ-----WLQEVPQRLQ--EELLIQPRHLPIKEVD 218
            .|.::..|::..|...:|     |...:||..     |:::...:|.  ||       ..:.:|.
Frog   153 PGVKHKTSLTAEDCFDLG-----KTAYTDADYYHTELWMEQALSQLDAGEE-------SSLDKVM 205

  Fly   219 ALRLLAEAQIKDQNYSEALPLLHNCLKLQPHDAR----VLRLWKKTTDFIENQPDQSPTENKKRN 279
            .|..|:.|..:..:..:||.|....|:|.|...|    :..:..|.::...:.|.:......::.
Frog   206 VLDYLSYAVYQQGDLDKALTLTKRSLELDPEHQRGNGNLRHIMSKESNKSSSSPSEGAELRTRKG 270

  Fly   280 VP----IANAFKLSCNGPLESST-----RLHC-FYNFTTTPFLRLAPLKTEQIGLDPYVVLYHEV 334
            .|    ....::..|.|.....|     ||.| :::....|.|.|:|.|.|.....|.:|.||::
Frog   271 RPKDHLEKEKYEKLCRGEGVKMTSRRQKRLFCRYFDGKKDPLLILSPTKQEDEWDKPRIVRYHDI 335

  Fly   335 LSAREISMLIGKAAQNMKNTKIHKERAVPKKNRG---------------RTAKGFWLKKESNELT 384
            :|..|||.:              ||.|.|:..|.               |..|..||....:.:.
Frog   336 ISDEEISKV--------------KELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVV 386

  Fly   385 KRITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSRYSIDLGDRIATVL 449
            .|:.|||..:||.|::.:|..||.||||||.|..|   |||......|...:  :..|:|:||.|
Frog   387 ARLNRRIEGVTGLDMSTAEELQVANYGIGGQYEPH---FDFLRKYEPDAFKK--LGTGNRVATWL 446

  Fly   450 FYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNGDPRTRHAACPVIVGSKWVMTEWIRE 514
            ||::|||.||||||.:||..|.|:.|||:|||||...|.||..||||||||:||:|||..:||.|
Frog   447 FYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHE 511

  Fly   515 KRQIFIRPC 523
            :.|.|.|||
Frog   512 RGQEFRRPC 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31013	NP_733394.3	P4Ha_N	31..160	CDD:285528	32/128 (25%)
		TPR_11	178..248	CDD:290150	17/76 (22%)
		TPR repeat	211..246	CDD:276809	8/34 (24%)
		P4Hc	336..513	CDD:214780	80/191 (42%)
p4ha1	XP_031761963.1	P4Ha_N	24..111	CDD:400573	22/86 (26%)
p4ha1	XP_031761963.1	P4Hc	337..510	CDD:214780	80/191 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110