DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Traf-like and Traf1

DIOPT Version :9

Sequence 1:	NP_727976.1	Gene:	Traf-like / 32611	FlyBaseID:	FBgn0030748	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001258169.1	Gene:	Traf1 / 687813	RGDID:	1596290	Length:	409	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	94/370 - (25%)
Similarity:	158/370 - (42%)	Gaps:	82/370 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 GTIRSVL-NEEIRQRLHLITDVGNIRKQNQVVEDWTRETEKAMDDLRRQMEEETNRKAFAIEQNQ 186
            |:.:||. :|...|..||...:|       |:::|           :............|:|||.
  Rat    92 GSPQSVQEHEATSQSSHLYLLLG-------VLKEW-----------KSSPGPNLGSAPMALEQNL 138

  Fly   187 LDVQYCCDITQSLKEQVESRLDEAQKLVNQLSADVTYH----QNQLNDNILKLEELIFENERLNR 247
            .::|                |.||.::...|..| .|.    ::|        |||..::  |.:
  Rat   139 SELQ----------------LQEAVEVTGDLEVD-CYRAPCCESQ--------EELALQH--LLK 176

  Fly   248 EKFF-QIEEFLQ-------QINEDIKTK---LGNSDYVTSKQATLDYEVKNVKNIVCETEERCDK 301
            ||.. |:||.|:       .:|::::..   |..|.:    |:.||.|  :|.|:    |:|..:
  Rat   177 EKLLAQLEEKLRVFANIVAVLNKEVEASHLALAASIH----QSQLDRE--HVLNL----EQRVVE 231

  Fly   302 LDRALHQTMQNISDLETQMAMQQRIASVQNIRGHLIWRIKDYSKKLEESKQYDTI-LHSAMFSNK 365
            |.:.|.|..|.:..||..:    |:....:..|..:|:|.:.:|:..||....|: |.|..|...
  Rat   232 LQQTLAQKDQVLGKLEHSL----RLMEEASFDGTFLWKITNVTKRCHESVCGRTVSLFSPAFYTA 292

  Fly   366 AFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCT--NVADA--E 426
            .:||.|.|.:||||.|:.|..::...:.::.||||.||.||.|.:...::.||..  :..||  .
  Rat   293 KYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAIDAFRP 357

  Fly   427 DYVKTIFVRKKSDDFIQSNQYFHIPHKVITS--RNYLRNDSMFIE 469
            |.....|.|.:|:..:.|......|...:.|  ..|:::|:||::
  Rat   358 DLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLK 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587
Traf-like	NP_727976.1	MATH_TRAF_C	334..473	CDD:238168	44/143 (31%)
Traf1	NP_001258169.1	TRAF_BIRC3_bd	180..237	CDD:406958	16/66 (24%)
Traf1	NP_001258169.1	MATH_TRAF1	260..406	CDD:239748	44/143 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10131
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910