DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf-like and Rnf151

DIOPT Version :9

Sequence 1:	NP_727976.1	Gene:	Traf-like / 32611	FlyBaseID:	FBgn0030748	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_080481.1	Gene:	Rnf151 / 67504	MGIID:	1914754	Length:	239	Species:	Mus musculus

Alignment Length:	187	Identity:	39/187 - (20%)
Similarity:	70/187 - (37%)	Gaps:	46/187 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KSSSRKDLTEQNQYQNQNENQNQPKSTTIVKYE---KSSCLFCNEWFDAQTFTEHLIHCGQVLEE 66
            |..:|:.:.|.|:.:.           ||.:.:   |::...|.:........||...|...|..
Mouse    59 KEVTRRKMVEVNKLRK-----------TIGRLQVKCKNAAAGCLDTHPLAHRKEHQDSCPFELMA 112

  Fly    67 CPN-GCQAFIPRIRMRSHLKECPRN-------------------QHNLSNQQRMSVSMDRLDRQS 111
            ||| ||...:.|..:..|.:.|.:|                   .||...:.|.:    .:.|..
Mouse   113 CPNEGCTVQVLRGVLDEHRQHCQQNGQQRCPLGCGSTLAALEGEHHNCYRELRDA----WVQRHE 173

  Fly   112 DQRLLVIEQDVGTIR------SVLNEEIRQRLHLITDVGNIRKQNQVVE-DWTRETE 161
            ..|.|::.. :|.:|      |::::::.|..:.:.|..|:....||.| :.|.|.|
Mouse   174 RNRTLLLGL-LGRVRRVHLTTSIIHQQLAQLSNFLEDDDNLLLNAQVQETEVTPEAE 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	11/34 (32%)
Traf-like	NP_727976.1	MATH_TRAF_C	334..473	CDD:238168
Rnf151	NP_080481.1	RING	20..61	CDD:238093	1/1 (100%)
Rnf151	NP_080481.1	Sina	83..>134	CDD:302762	13/50 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810