DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Traf-like and Pdzrn3

DIOPT Version :9

Sequence 1:NP_727976.1 Gene:Traf-like / 32611 FlyBaseID:FBgn0030748 Length:474 Species:Drosophila melanogaster
Sequence 2:NP_061372.2 Gene:Pdzrn3 / 55983 MGIID:1933157 Length:1063 Species:Mus musculus


Alignment Length:386 Identity:66/386 - (17%)
Similarity:139/386 - (36%) Gaps:112/386 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 EECPNGCQAFIPRIRMRSHLKECPRNQ--------HNLSNQQRMSVSM-DRLDRQSDQRLLVIEQ 120
            ||.|.....:.|...|....::..|.:        :.:::|.::.::: .|.|.:.|..:.:.|.
Mouse   388 EEHPASHDYYDPNDYMGDIHQDMDREELELEEVGLYRMNSQDKLGLTVCYRTDDEDDIGIYISEI 452

  Fly   121 DVGTIRS------------------VLNEEIRQRLHLITDVGN-------IRKQNQVVEDWTRET 160
            |..:|.:                  |.|.|  :.:.|:|...|       .|.:.|:.|.|..:.
Mouse   453 DPNSIAAKDGRIREGDRIIQINGIEVQNRE--EAVALLTSEENKNFSLLIARPELQLDEGWMDDD 515

  Fly   161 EK-AMDDLRRQMEEETNRKAFAIEQNQLDVQYCCDITQSLKEQVESRLDEAQKLVNQLSADVTYH 224
            .. .:|||...|.||.:.:|         :|:...:.|..|.:.:....:        :|.:..:
Mouse   516 RNDFLDDLHMDMLEEQHHQA---------MQFTASVLQQKKHEEDGGTTD--------TATILSN 563

  Fly   225 QNQLNDNILKLEELIFENERLNREKFFQIEEFLQQIN-----------EDIKTKLGNSDYVTSKQ 278
            |::.:..:.:.:|....:|...:|.  ..|:.....|           :|   .||:.|...|.:
Mouse   564 QHEKDSGVGRTDESTRNDESSEQEN--NGEDATASANPLAGQRKLTCSQD---TLGSGDLPFSNE 623

  Fly   279 ATL-----DYEVKNVKNIVCE-----TEERC--------------DKLDRALHQTMQNISDLETQ 319
            :.:     |.:...:....||     .|.:|              ..||.|.....::: |.|.:
Mouse   624 SFISADCTDVDYLGIPEDECERFRELLELKCQVQSASPYSLYYPSSPLDAAGKSDPESV-DKELE 687

  Fly   320 MAMQQRIASVQ-----NIRGHLIWRIKDYSKKLEESKQYDTILHSAMFSNKAFGYALRLDI 375
            : :.:.:.|::     .:|.|.:       ::|:|..:...:||.:.|.|    |...:|:
Mouse   688 L-LNEELRSIELECLSIVRAHKM-------QQLKEQYRESWMLHHSGFRN----YNTSVDV 736

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Traf-likeNP_727976.1 zf-TRAF_2 <54..88 CDD:292587 5/22 (23%)
MATH_TRAF_C 334..473 CDD:238168 9/42 (21%)
Pdzrn3NP_061372.2 RING 17..57 CDD:238093
Sina 69..>132 CDD:302762
PDZ 246..338 CDD:214570
PDZ_signaling 424..488 CDD:238492 10/65 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 545..602 8/66 (12%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 746..798
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 834..853
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0297
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.