Protein Alignment Traf-like and traf6

DIOPT Version :9

• Sequence 1: NP_727976.1
• Gene: Traf-like / 32611
• FlyBaseID: FBgn0030748
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001008162.2
• Gene: traf6 / 493524
• XenbaseID: XB-GENE-480628
• Length: 558
• Species: Xenopus tropicalis
• Alignment Length: 517
• Identity: 105/517 - (20%)
• Similarity: 188/517 - (36%)
• Gaps: 132/517 - (25%)

  Fly     8 SRKDLTEQNQYQNQNENQNQPKSTTIVKYE------KSSCLFCNEWFDAQTFTEHLIHCGQVLEE 66
            |.:|...:....|::..:||.......|.|      |.....|.|..:.:....||:.|.....|
 Frog    99 SIRDAGHKCPVDNESLMENQLFPDNFAKREILSLRVKCPSQGCTETMELRHLERHLVRCDFAGVE 163

  Fly    67 CPNGCQAFIPRIRMRSH-LKECPRNQHNLSNQQRMSVSM---DRLDRQSDQRLLVIEQDVGTIRS 127
            | :.||:..|:..::.| .:||||.|....|   .:|:|   |:|:......|..:     |...
 Frog   164 C-SQCQSSFPKYSLQKHKFEECPRRQIFCEN---CAVAMALEDKLNHDQTCPLAYV-----TCEY 219

  Fly   128 VLNEEIRQRL--HLITD------------VGNIRKQNQVVEDWTRETEKAMDDLRRQMEEETNRK 178
            .....||:::  |...|            .|...|..:             :||.|.::|.|...
 Frog   220 CQTNLIREQMPAHYSMDCTMAPIPCMYYEFGCTEKMQR-------------NDLARHLQEFTQAH 271

  Fly   179 AFAIEQ-------------NQLDVQYCCDITQSLKEQVESRLDEAQKLVNQLSADVTYHQNQLND 230
            ...:.|             :..|:.:|          ..|:.:.|...|..:.:..|..||....
 Frog   272 MRMMAQTLRSFSSSVTPTSHMPDISFC----------DPSQFEPAPPSVATVHSTHTPSQNDCTQ 326

  Fly   231 NILKLEELIFENERLNREKFFQIEEFLQQINEDIKTKLGNSDYVTSKQATLDYEVKNVKNIVCET 295
            ....|.|.|                      |.::.:|...|:             .::.::.:.
 Frog   327 ETRNLRETI----------------------EQLEGRLVRQDH-------------QIRELIAKM 356

  Fly   296 EERCDKLDRALHQTMQNISDLETQMAMQQRIASVQNIRGHLIWRIKDYSKKLE-ESKQYDTILHS 359
            |.:|..::...| |::::.:...:|..||       ..|..||||.:::..|: :.::...::||
 Frog   357 ETQCTYVNELKH-TIRSLDNRLGEMESQQ-------CSGIFIWRINNFNSLLKNQEEERPVVIHS 413

  Fly   360 AMFSNKAFGYALRLDIYLNGKGTWKGRNMIAC-LNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVA 423
            ..|.....||.|.|.::|......:..|.|:. ::.:.||||.||.||.:....:.|.||...||
 Frog   414 QGFYTGKPGYKLCLRLHLQLPSAQRCANYISLFVHTMQGEYDSLLPWPLQGTIRLSILDQSEGVA 478

  Fly   424 --DAEDYVKT-----IFVR------KKSDDFIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 472
              |.|:.:.|     .|.|      .|...::   .:.|:  :.:..|.|::||::.:...|
 Frog   479 MQDQEEVMDTKPELLAFQRPTVARNPKGFGYV---TFMHL--QALKQRQYVKNDTLLVRCSV 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	10/34 (29%)
		MATH_TRAF_C	334..473	CDD:238168	41/154 (27%)
traf6	NP_001008162.2	mRING-HC-C3HC3D_TRAF6	69..126	CDD:319557	5/26 (19%)
		modified RING-HC finger (C3HC3D-type)	72..110	CDD:319557	2/10 (20%)
		PLN03086	<134..220	CDD:178635	24/94 (26%)
		zf-TRAF	206..263	CDD:280357	10/74 (14%)
		Smc	<322..>384	CDD:224117	12/97 (12%)
		MATH_TRAF6	387..536	CDD:239745	41/154 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910