Protein Alignment Traf-like and traf4

DIOPT Version :9

• Sequence 1: NP_727976.1
• Gene: Traf-like / 32611
• FlyBaseID: FBgn0030748
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001005074.1
• Gene: traf4 / 448646
• XenbaseID: XB-GENE-990354
• Length: 470
• Species: Xenopus tropicalis
• Alignment Length: 526
• Identity: 98/526 - (18%)
• Similarity: 157/526 - (29%)
• Gaps: 248/526 - (47%)

  Fly     9 RKDLTEQNQYQNQNENQNQPKSTTIVKYEKSSCLFCNEWFDAQTFTEHLIHCGQVLEECPNGCQA 73
            |:||.|..|:       :.||       .|..|.||...|..:.:.:|...|.|....|.|.|.|
 Frog   123 RRDLPEHMQH-------DCPK-------RKVRCEFCGADFTGEAYEDHQGCCPQESVYCENKCGA 173

  Fly    74 FIPR---------------------------IRMRSHLKECPR------NQHNLSNQQRMSVSMD 105
            .:.|                           ..::||..:|||      ||..:::..|..:|..
 Frog   174 RMMRRVLSQHSLVECPKRTQPCPYCNKEFVFDTIQSHQYQCPRYPTPCPNQCGIASIAREDLSNH 238

  Fly   106 RLDRQSDQRLLVIEQDVG--------TIRSVLNEEIRQRLHLITDVGNIRKQNQVVEDWTRETEK 162
            ..|..|...:|...:|.|        ||...|.|.:|..|.:::.:.: |::.:::|
 Frog   239 LKDSCSSALVLCPFKDSGCKHRGPKITISRHLEENMRAHLSMMSSLVS-RQRQEILE-------- 294

  Fly   163 AMDDLRRQMEEETNRKAFAIEQNQLDVQYCCDITQSLKEQVESRLDEAQKLVNQLSADVTYHQNQ 227
                ||:|:||                                           ||
 Frog   295 ----LRKQVEE-------------------------------------------LS--------- 303

  Fly   228 LNDNILKLEELIFENERLNREKFFQIEEFLQQINEDIKTKLGNSDYVTSKQATLDYEVKNVKNIV 292
                                                          |:|:
 Frog   304 ----------------------------------------------VSSE--------------- 307

  Fly   293 CETEERCDKLDRALHQTMQNISDLETQMAMQQRIASVQNIRGHLIWRIKDYSKKLEESK---QYD 354
                                                     |.|||:|.|||:|::|:|   .::
 Frog   308 -----------------------------------------GVLIWKISDYSRKVQEAKVRGNFE 331

  Fly   355 TILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQC 419
            :.  |..|....:||.|::..:|||.|:.:|..:...:.||.||||.||.||...:....:.||.
 Frog   332 SF--SPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQS 394

  Fly   420 TNVADAEDYVKTIF--------------VRKKSDDFIQSNQYFHIP----HKVITSRNYLRNDSM 466
            ........::...|              .|...|   :|...|..|    |:.|..|||:|::::
 Frog   395 DPSLSKPQHITETFNPDPNWKNFQKPTGSRNSLD---ESTLGFGYPKFISHEDIRKRNYVRDNAI 456

  Fly   467 FIEVRV 472
            |:...|
 Frog   457 FLRASV 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	10/60 (17%)
		MATH_TRAF_C	334..473	CDD:238168	47/160 (29%)
traf4	NP_001005074.1	mRING-HC-C3HC3D_TRAF4	15..59	CDD:319555
		modified RING-HC finger (C3HC3D-type)	18..57	CDD:319555
		PLN03086	<88..211	CDD:178635	21/101 (21%)
		zf-TRAF	102..156	CDD:280357	12/46 (26%)
		zf-TRAF	210..269	CDD:280357	15/58 (26%)
		MATH_TRAF4	308..463	CDD:239750	47/160 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000