DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Traf-like and rnf41

DIOPT Version :9

Sequence 1:	NP_727976.1	Gene:	Traf-like / 32611	FlyBaseID:	FBgn0030748	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_998681.1	Gene:	rnf41 / 406837	ZFINID:	ZDB-GENE-040426-2920	Length:	318	Species:	Danio rerio

Alignment Length:	312	Identity:	56/312 - (17%)
Similarity:	111/312 - (35%)	Gaps:	108/312 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 FCN----EWFDAQTF---------TEHLIHCGQVLE--------ECPN---GCQAFIPRIRMRSH 83
            |||    :||..|..         ..||....:::.        .|.|   ||.|.:...:::||
Zfish    38 FCNACITQWFAQQQICPVDRTVVTLAHLRPVPRIMRNMLSKLQISCDNAGFGCTATLRLDQLQSH 102

  Fly    84 LKECPRN-QHNLSNQQRMSVSMDRLDRQSDQRLLVIEQDVGTIRSVLNEEIRQRLHLITDVGNIR 147
            ||:|..| :..::.::...:.|.: |...:...      :..:|||:.::
Zfish   103 LKDCEHNPKRPVTCEEGCGLEMPK-DEMPNHNC------IKHLRSVVQQQ--------------- 145

  Fly   148 KQNQVVEDWTRETEKAMDDLRRQMEEETNRKAFAIEQNQLDVQYCCDITQSLKEQVESRLDEAQK 212
             |.::.     :.||...:.:.|:.|:           :.|:|    :.::....:.|
Zfish   146 -QTKIA-----DLEKTAAEHKHQLAEQ-----------KRDIQ----LLKAYMRAIRS------- 182

  Fly   213 LVNQLSADVTYHQNQLNDNILKLEELIFENERLNREKFFQIEEFLQQINEDIKTKLGNSDYVTSK 277
                           .|.|:..|||.|..||         |.|::..:.....|:.|.  .:::.
Zfish   183 ---------------ANPNLQNLEESIEYNE---------ILEWVNSLQPARVTRWGG--MISTP 221

  Fly   278 QATLDYEVKNVKNIV---CETEERCDKLDRALHQTM-QNISDLETQMAMQQR 325
            .|.|...:|  ::::   |......|.::.|..:.. |.::.|||:. |.:|
Zfish   222 DAVLQAVIK--RSLIDSGCPLSIVNDLIENAHERNWPQGLATLETRQ-MNRR 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	11/44 (25%)
Traf-like	NP_727976.1	MATH_TRAF_C	334..473	CDD:238168
rnf41	NP_998681.1	RING	18..55	CDD:238093	6/16 (38%)
rnf41	NP_998681.1	USP8_interact	137..315	CDD:286082	35/206 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900