DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf-like and elgi

DIOPT Version :9

Sequence 1:	NP_727976.1	Gene:	Traf-like / 32611	FlyBaseID:	FBgn0030748	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	39/173 - (22%)
Similarity:	68/173 - (39%)	Gaps:	39/173 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VKYEKSSCLFC-NEWFDAQ---------TFTEHLIHCGQVL-----------EECPNGCQAFIPR 77
            |..|.:.|..| |||...|         ..|.:|....::|           :..|.||.|.:..
  Fly    32 VMCEHAFCRGCINEWLTRQPTCPVDRNSLTTANLRAVPRILRNLLSRLSITCDNAPYGCTAVLKL 96

  Fly    78 IRMRSHLKEC---PRNQHNLSNQQRMSVSMDRLDRQS---DQRLLVIEQ--DVGTIRSVLNEEIR 134
            ....|||.||   |:............:..|.|...:   :.|.|:::|  .:|.::|.|.:
  Fly    97 DAYNSHLDECIHNPKRPFPCEKGCGFDIPKDELKDHNCVRELRTLIVKQTEKMGELKSELTD--- 158

  Fly   135 QRLHLITDVGNIRKQNQVVEDWTRE---TEKAMDDLRRQMEEE 174
            |:|    .:..::::.|:.:|:.|.   :..||..:..|||.:
  Fly   159 QQL----TINELKRELQLFKDFMRAMRVSNPAMRAIADQMERD 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	12/47 (26%)
Traf-like	NP_727976.1	MATH_TRAF_C	334..473	CDD:238168
elgi	NP_001261904.1	RING	17..55	CDD:238093	8/22 (36%)
		Sina	83..>157	CDD:302762	17/73 (23%)
		USP8_interact	137..315	CDD:286082	16/68 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900