DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf-like and rnf41l

DIOPT Version :9

Sequence 1:	NP_727976.1	Gene:	Traf-like / 32611	FlyBaseID:	FBgn0030748	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	XP_002664951.1	Gene:	rnf41l / 337495	ZFINID:	ZDB-GENE-030131-9441	Length:	292	Species:	Danio rerio

Alignment Length:	186	Identity:	36/186 - (19%)
Similarity:	72/186 - (38%)	Gaps:	40/186 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 CLF----CNEWFDAQTFTEHLIHCGQVLEECPN-GCQAFIPRIRMRSHLKECPRN---------- 90
            |:|    |......::...|...|...|..|.| ||...:.|..:.:||..|..:
Zfish    82 CVFRPQGCEVICALESIHRHEQQCDYALLNCTNTGCPVQVSRRSLEAHLCVCEYSSRVCASGCGY 146

  Fly    91 --------QHNLSNQQRMSVSMDRLDRQSDQRLLVIEQDVGTIRSVLNEEI-RQRLHLITDVGNI 146
                    |||..::.|..:.|.|.:         ::..|..:|..:...: .||.|::.....:
Zfish   147 TILNTDEAQHNCVSELRAELDMLRAE---------LDCKVEEVRHEMESRLDSQRRHMVQKESLL 202

  Fly   147 RKQNQVVEDWTRETEKAMDDLRRQMEEETNRKAFAIEQNQLDVQYCCDITQSLKEQ 202
            |.:   |::...:..:.|.|:|..:..|..|:. .:|:.:|:.   .::.:.||::
Zfish   203 RSE---VDELKAQLSRVMSDVRVLLGAERARRQ-ELERAELEK---AELLELLKKE 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	10/34 (29%)
Traf-like	NP_727976.1	MATH_TRAF_C	334..473	CDD:238168
rnf41l	XP_002664951.1	zf-RING_2	18..53	CDD:290367
		Sina	82..>130	CDD:302762	11/47 (23%)
		DUF1640	150..>234	CDD:285090	18/96 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810