Protein Alignment Traf-like and Traf1

DIOPT Version :10

• Sequence 1: NP_727976.1
• Gene: Traf-like / 32611
• FlyBaseID: FBgn0030748
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_033447.2
• Gene: Traf1 / 22029
• MGIID: 101836
• Length: 409
• Species: Mus musculus
• Alignment Length: 354
• Identity: 80/354 - (22%)
• Similarity: 138/354 - (38%)
• Gaps: 102/354 - (28%)

  Fly   152 VVEDWTRE-----------TEKAMDDLRRQ--------MEEETNRKAFAIEQNQLDVQYCCDITQ 197
            |:::|...           .|:.:.:|:.|        :|.:..|......|.:|.:|:.  :.:
Mouse   115 VLKEWKSSPGSNLGSAPMALERNLSELQLQAAVEATGDLEVDCYRAPCCESQEELALQHL--VKE 177

  Fly   198 SLKEQVESRLDEAQKLVNQLSADV---------TYHQNQLN-DNILKLEELIFENERLNREKFFQ 252
            .|..|:|.:|.....:|..|:.:|         :.||:||: ::||.||:.:.|
Mouse   178 KLLAQLEEKLRVFANIVAVLNKEVEASHLALAASIHQSQLDREHILSLEQRVVE----------- 231

  Fly   253 IEEFLQQINEDIKTKLGNSDYVTSKQATLDYEVKNVKNIVCETEERCDKLDRALHQTMQNISDLE 317
                |||       .|...|.|..                        ||:.:|
Mouse   232 ----LQQ-------TLAQKDQVLG------------------------KLEHSL----------- 250

  Fly   318 TQMAMQQRIASVQNIRGHLIWRIKDYSKKLEESKQYDTI-LHSAMFSNKAFGYALRLDIYLNGKG 381
                   |:....:..|..:|:|.:.:|:..||....|: |.|..|....:||.|.|.:||||.|
Mouse   251 -------RLMEEASFDGTFLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDG 308

  Fly   382 TWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCT--NVADA--EDYVKTIFVRKKSDDFI 442
            :.|..::...:.::.||||.||.||.|.:...::.||..  :..||  .|.....|.|.:|:..:
Mouse   309 SGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAIDAFRPDLSSASFQRPQSETNV 373

  Fly   443 QSNQYFHIPHKVITS--RNYLRNDSMFIE 469
            .|......|...:.|  ..|:::|:||::
Mouse   374 ASGCPLFFPLSKLQSPKHAYVKDDTMFLK 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	SMC_prok_B	<131..>336	CDD:274008	37/212 (17%)
		MATH_TRAF_C	334..473	CDD:238168	44/143 (31%)
Traf1	NP_033447.2	TRAF_BIRC3_bd	175..238	CDD:465226	20/84 (24%)
		MATH_TRAF1	260..406	CDD:239748	44/143 (31%)