DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf-like and trf-2

DIOPT Version :9

Sequence 1:	NP_727976.1	Gene:	Traf-like / 32611	FlyBaseID:	FBgn0030748	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_491534.2	Gene:	trf-2 / 172151	WormBaseID:	WBGene00022454	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	47/208 - (22%)
Similarity:	89/208 - (42%)	Gaps:	49/208 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   303 DRALHQTM--QNISDLETQMAMQQRIASVQNIRGHLIW------RIKDYSK-------------- 345
            ||.||..:  |:::.:.|::.:||. |.|....|.|.:      ..:.|..
Worm   109 DRNLHLVLLCQSLNPIRTKINIQQS-AYVDKYVGMLQYMSIAESAFEKYGSQHTFRIPKIGLTVV 172

  Fly   346 KLEESKQYDTILHSAMFSNKAFGYALRLDI--YLNGKGTWKGRNMIACLNVLSGEYDPLLAWP-- 406
            |..::|.:.:| :|..|.:..:||.:....  |.:|....:..::..||  :.||:|.:|.||
Worm   173 KATKNKSHRSI-YSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCL--MKGEWDDILEWPFR 234

  Fly   407 CRLQAEIIIRDQCTNVADAEDYVKTIFVRKKSD--DFIQ-----SNQYF----HIPHKVITSRNY 460
            |.:...|:..|:      .|...|||:|.:..:  :|::     .|..|    .:|...:|  .:
Worm   235 CDVTFSILSDDK------KELLTKTIYVNEMPEIQEFLERPEGLRNGTFGFQNFLPLAKVT--EF 291

  Fly   461 LRNDSMFIEVRVL 473
            ..:..:||:::||
Worm   292 AADGDIFIQIKVL 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587
Traf-like	NP_727976.1	MATH_TRAF_C	334..473	CDD:238168	35/173 (20%)
trf-2	NP_491534.2	MATH_TRAF_C	158..304	CDD:238168	32/156 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770