DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Traf-like and Lnx1

DIOPT Version :9

Sequence 1:	NP_727976.1	Gene:	Traf-like / 32611	FlyBaseID:	FBgn0030748	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001153049.1	Gene:	Lnx1 / 16924	MGIID:	1278335	Length:	728	Species:	Mus musculus

Alignment Length:	88	Identity:	21/88 - (23%)
Similarity:	31/88 - (35%)	Gaps:	25/88 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KSTTIVKYEKSSCL---FCNEWFDAQTFTEHLIHCGQVLEECPNGCQAFIPRIRMRSHLK-ECPR 89
            |...:...:|||.|   ..|:......|||   ||.:||:.|.           ::.|.: .|..
Mouse    84 KPVVLQHCKKSSILVNKLLNKLLVTCPFTE---HCTEVLQRCD-----------LQHHFQTSCKG 134

  Fly    90 NQHNLSNQQRMSVSMDRLDRQSD 112
            ..|       ..::.||..|..|
Mouse   135 ASH-------YGLTKDRKRRSQD 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	zf-TRAF_2	<54..88	CDD:292587	8/34 (24%)
Traf-like	NP_727976.1	MATH_TRAF_C	334..473	CDD:238168
Lnx1	NP_001153049.1	mRING-HC-C3HC3D_LNX1	42..83	CDD:319693
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	185..220
		NPXY motif	185..188
		Interaction with MAGEB18. /evidence=ECO:0000250	186..244
		PDZ_signaling	276..360	CDD:238492
		PDZ_signaling	384..464	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	481..500
		PDZ_signaling	506..589	CDD:238492
		PDZ_signaling	637..721	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900