Protein Alignment Traf-like and traf3

DIOPT Version :10

• Sequence 1: NP_727976.1
• Gene: Traf-like / 32611
• FlyBaseID: FBgn0030748
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_002938036.2
• Gene: traf3 / 100498216
• XenbaseID: XB-GENE-968262
• Length: 569
• Species: Xenopus tropicalis
• Alignment Length: 505
• Identity: 109/505 - (21%)
• Similarity: 204/505 - (40%)
• Gaps: 146/505 - (28%)

  Fly     9 RKDLTEQNQYQNQNENQNQPKSTTIVKYEKSSCLFCNEWFDAQTFTEHL-IHCGQVLEECPNGCQ 72
            ||||::..:              ...||.::.|.||..........:|. :.|..|:..||:.|.
 Frog   162 RKDLSDHIE--------------KTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCS 212

  Fly    73 A-FIPRIRMRSHLKECPRNQHNLSNQQRMSVSMDRLDRQSDQRLLVIEQDVGTIRSVLNEEIRQR 136
            . .:.|..:.:||.||. |..:..:.:|...:..                 ||     |::|:..
 Frog   213 VKSLLRSELNAHLLECV-NAPSTCSFKRYGCTFK-----------------GT-----NQQIKAH 254

  Fly   137 LHLITDVGNIRKQNQVVEDWTRETEKAMDDLRRQMEEETNRKAFAIEQNQLDVQYCCDITQSLKE 201
                 :..:..:...::::|:...|..:..|:.:..|:  .|:..|..||:     |    |.:.
 Frog   255 -----EASSAVQHVNLMKEWSNYLEAKVSMLQNESSEK--NKSIQILHNQM-----C----SFEI 303

  Fly   202 QVESRLDEAQKLVNQLSADVTYHQNQLNDNILKLEELIFENERLNREKFFQIEEFLQQINEDIKT 266
            ::|.                  |:.||.:|..::.:                   ||::.|
 Frog   304 EIER------------------HKEQLRNNEARIIQ-------------------LQRVIE---- 327

  Fly   267 KLGNSDYVTSKQATLDYEVKNVKNIVCETEERCDKLDRALHQTMQN-ISD--------------- 315
              |.:|    |...||.|::|::    :|.:..|.: ::.::::|| :|.
 Frog   328 --GQAD----KLKDLDKEIRNLR----QTGDEADGM-KSNYESLQNRLSQLEVMAKNAASWNPGV 381

  Fly   316 LETQMAMQQRIASVQNIR-----------------GHLIWRIKDYSKKLEESKQYDTI-LHSAMF 362
            ||||:....::.||.:||                 |.|||:|:||.::.:|:....|: |:|..|
 Frog   382 LETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPF 446

  Fly   363 SNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQ---CTNVAD 424
            ....|||.:...:||||.|..||.::.....::.||||.||.||.:.:..:::.||   ..::.|
 Frog   447 YTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGD 511

  Fly   425 A--EDYVKTIFVRKKSDDFIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 472
            |  .|...:.|.:...:..|.|.....:...|:.:..|:::|::||:|.|
 Frog   512 AFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIV 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	SMC_prok_B	<131..>336	CDD:274008	40/237 (17%)
		MATH_TRAF_C	334..473	CDD:238168	45/145 (31%)
traf3	XP_002938036.2	RING-HC_TRAF3	54..95	CDD:438302
		zf-TRAF	139..195	CDD:280357	9/46 (20%)
		zf-TRAF	200..250	CDD:280357	15/72 (21%)
		SMC_N	<255..>432	CDD:481474	45/239 (19%)
		MATH_TRAF3	382..564	CDD:239746	53/180 (29%)