Protein Alignment Traf-like and traf2

DIOPT Version :10

• Sequence 1: NP_727976.1
• Gene: Traf-like / 32611
• FlyBaseID: FBgn0030748
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_031746908.1
• Gene: traf2 / 100494415
• XenbaseID: XB-GENE-493460
• Length: 527
• Species: Xenopus tropicalis
• Alignment Length: 443
• Identity: 91/443 - (20%)
• Similarity: 171/443 - (38%)
• Gaps: 91/443 - (20%)

  Fly    38 KSSCLFCNEWFDAQTFTEHLIHCGQVLEECPNGC-QAFIPRIRMRSHLKECPRNQHNLSNQQRMS 101
            |.:|.:|...|.......|...|.:....| .|| :..|||.:...|:|.|.|
 Frog   163 KLNCRYCKLSFYFPDIKAHDEICPKFPMTC-EGCGRKKIPREKFPDHVKICGR------------ 214

  Fly   102 VSMDRLDRQSDQRLLVIEQDVGTIRSVLNEEIRQRLHLITDVGNIRKQNQVVEDWTRETEKAMDD 166
                       .::......||....|.|::..:.     :..::.:....|.|:.:...|..:|
 Frog   215 -----------CKVPCRYAAVGCTEMVENDKCLEH-----ENKSLAEHLAKVWDYIQHGRKEQND 263

  Fly   167 LRRQMEEETNRKAFAIEQNQLDVQYCCDITQSLKEQVESRLDEAQKLVNQLSADVTYHQNQLNDN 231
            |             ::....|.||                            .......|...:|
 Frog   264 L-------------SVRMGSLSVQ----------------------------GSPAPPANAPPNN 287

  Fly   232 ILKLEELIFENERLNREKFFQIEEFLQQINEDIKTKLGNSDYVTSKQATLDYEVKNVKNIVCETE 296
            ..|:.|::.:.:.|:: |....|..:..:|.:::    .|.:...:.|.   :::..:..|....
 Frog   288 SAKVAEMLLKFDTLDK-KNTTFENIVSVLNREVE----RSSHAAEELAR---QLRAAQEKVEALT 344

  Fly   297 ERCDKLDRALHQTMQNISDLETQMAMQQRIASVQNIRGHLIWRIKDYSKKLEE--SKQYDTILHS 359
            .:..:|:|.|.|....:::|||:|    :.:.:....|..||:|.::.||.::  :.:...:...
 Frog   345 TKVRQLERTLGQKELIVAELETRM----QESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSP 405

  Fly   360 AMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCT--NV 422
            ..::|| :||.:.|.|||||.||.:..::.....|:.|..|.||.||...:..:::.||..  :|
 Frog   406 PFYTNK-YGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNREHV 469

  Fly   423 ADA--EDYVKTIFVRKKSDDFIQSN-QYFHIPHKVITSRNYLRNDSMFIEVRV 472
            .||  .|...:.|.|..|:..|.|. ..|....|:....:|:|:|::|::|.|
 Frog   470 IDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIV 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Traf-like	NP_727976.1	SMC_prok_B	<131..>336	CDD:274008	28/204 (14%)
		MATH_TRAF_C	334..473	CDD:238168	44/146 (30%)
traf2	XP_031746908.1	RING-HC_TRAF2	34..76	CDD:438301
		zf-TRAF	181..238	CDD:280357	16/80 (20%)
		TRAF_BIRC3_bd	293..356	CDD:465226	11/70 (16%)
		MATH	362..523	CDD:445786	48/166 (29%)