Protein Alignment CG4301 and DRS2

DIOPT Version :9

• Sequence 1: NP_573125.1
• Gene: CG4301 / 32610
• FlyBaseID: FBgn0030747
• Length: 1342
• Species: Drosophila melanogaster
• Sequence 2: NP_009376.2
• Gene: DRS2 / 851207
• SGDID: S000000024
• Length: 1355
• Species: Saccharomyces cerevisiae
• Alignment Length: 1315
• Identity: 399/1315 - (30%)
• Similarity: 600/1315 - (45%)
• Gaps: 286/1315 - (21%)

  Fly    47 RVSTINDWLQIQIGGPQDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISL 111
            ||..|||.|.....|..|         |.|.:|||...||||:.|.::|.:.||.:||..:.|..
Yeast   183 RVIHINDSLANSSFGYSD---------NHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQ 238

  Fly   112 LID-SPVSPMTSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNSSPVTVIRDGKEAIIKSQ--DVI 173
            :.. ||.:..|::..|:.|:.|:|.|:..|||.|..:|..:|:|...:..:..:..::.:  |:.
Yeast   239 VPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIR 303

  Fly   174 PGELIVVERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLK----TLMVPRDLPTVDLPEMHK 234
            .|::|.|:.:..:|.|.::|.|::|.|.|:|.|||||||:|||    .:...:.:....|..|:
Yeast   304 VGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMN- 367

  Fly   235 LGIIECESPTTDLYSFNGKIELKGGEGRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQL 299
             |.:..|.|.:.||::.|.:.|   ..|.:|||.:.::|||:.::||..:.|..::||..:||..
Yeast   368 -GKVVSEQPNSSLYTYEGTMTL---NDRQIPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLR 428

  Fly   300 NSRLTRNKNASSETYINRFLIVILVALIAIVTLLYFLKRYNELFVIPKLTYLG-DATDSYSVKQF 363
            |:..|..|..:.|..|||.:|.:...||.::.:...............|:||. :.|:...:  |
Yeast   429 NATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVIMSTADAKHLSYLYLEGTNKAGL--F 491

  Fly   364 LQDYLSFLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINI 428
            .:|:|:|.|||:.|:||||:||:||.:...::.:..||:||..:||.|.||.||:|.||||||..
Yeast   492 FKDFLTFWILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEY 556

  Fly   429 LFSDKTGTLTKNEMNFQQCSINGNKFLFKKTRLEDEETKALLDINKFSANQRVFFQALSICHTVQ 493
            :|||||||||:|.|.|:.|||.|:.::.|   :.:::|..:
Yeast   557 IFSDKTGTLTRNIMEFKSCSIAGHCYIDK---IPEDKTATV------------------------ 594

  Fly   494 VASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGV 558
                                                                             
Yeast   595 ----------------------------------------------------------------- 594

  Fly   559 NSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVE 623
                           :||..|..||                     ..||.....||
Yeast   595 ---------------EDGIEVGYRK---------------------FDDLKKKLNDP-------- 615

  Fly   624 PTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAP--NAYLTNPVTASTPPAGVLF 686
                            |::|                      :|  |.:||...|..|
Yeast   616 ----------------SDED----------------------SPIINDFLTLLATCHT------- 635

  Fly   687 RSPSTTSRESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVY 751
                       ..|.|....:|                    .|||:||||.|||:..|:||
Yeast   636 -----------VIPEFQSDGSI--------------------KYQAASPDEGALVQGGADLG--- 666

  Fly   752 TGDDDETLRVRIVPPHMDYKRPFAKPR------EET-----FQRLHVLEFTSDRKRMSVIVRDTD 805
                              ||....||.      |||     :|.|::.||.|.|||||.|.|..|
Yeast   667 ------------------YKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPD 713

  Fly   806 GKKWIYTKGAESYVFPLCANSSAELVTKTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQ 870
            |...::.|||::.:.....:.:.:.|..|..|:.|:|..|||||.:|.|.|||.||:::.....:
Yeast   714 GSIKLFCKGADTVILERLDDEANQYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNE 778

  Fly   871 ANSSLENRKQLSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETAL 935
            |.::|:||.:..:|....||.||.|:||||:||.|||.|.:|:.:||.|||||||||||:.|||:
Yeast   779 AATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAI 843

  Fly   936 NIALSCGHIPPDAKKYFIMECKNREE----MLLHLNAL-DREIIFGIGQECALLIDGKSLGVAL- 994
            ||.:||..:..|.....|.| :.|::    :|..:||| :.::........||:|||||||.||
Yeast   844 NIGMSCRLLSEDMNLLIINE-ETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALE 907

  Fly   995 AEASSEFRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGI 1059
            .|.......||..|.||:|||:|||||:.||.::|..:.:...| ||||||||||||.||||:||
Yeast   908 PELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLA-IGDGANDVSMIQAAHVGVGI 971

  Fly  1060 MGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFS 1124
            .|.||.||||.||.|..:|..||:||||||.:...|:|:.:||.||||.......|.:.|...||
Yeast   972 SGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFS 1036

  Fly  1125 SSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFA 1189
            ..|:.:|..::.||:.:|..|...|.:.::..:...|.|.|||||.....:......|..|::..
Yeast  1037 GQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIING 1101

  Fly  1190 IYHSVIIFYFAFCFFYYNNVLLNYGQTVAFSCFGTLLMWTVVVVVNLKLWLESMYLSFWYIFTII 1254
            .:||.|:|......:.|...|..:|:......:|..:..|.|::|   |...::..:.|..||:|
Yeast  1102 FFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIV---LGKAALVTNQWTKFTLI 1163

  Fly  1255 I---SILGFVVTTVIYNVI--NLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQR 1314
            .   |:|.:::...||..|  :.:...:.|....:...|...||.:||..:..||.|:..:..:|
Yeast  1164 AIPGSLLFWLIFFPIYASIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKR 1228

  Fly  1315 ALNIKSFSIFPGKQR 1329
            ....:::.:....|:
Yeast  1229 MYEPETYHVIQEMQK 1243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	PhoLip_ATPase_N	57..121	CDD:292826	20/64 (31%)
		ATPase-Plipid	74..1317	CDD:273734	390/1274 (31%)
		E1-E2_ATPase	127..>345	CDD:278548	66/223 (30%)
		Cation_ATPase	<734..823	CDD:289987	34/99 (34%)
		HAD_like	<1036..1066	CDD:304363	22/29 (76%)
		PhoLip_ATPase_C	1068..1317	CDD:292829	73/253 (29%)
DRS2	NP_009376.2	ATPase-Plipid	198..1240	CDD:273734	391/1295 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910