DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4301 and AT1G68710

DIOPT Version :9

Sequence 1:	NP_573125.1	Gene:	CG4301 / 32610	FlyBaseID:	FBgn0030747	Length:	1342	Species:	Drosophila melanogaster
Sequence 2:	NP_001320718.1	Gene:	AT1G68710 / 843201	AraportID:	AT1G68710	Length:	1226	Species:	Arabidopsis thaliana

Alignment Length:	1366	Identity:	422/1366 - (30%)
Similarity:	625/1366 - (45%)	Gaps:	325/1366 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 QIGGP------------QDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIIS 110
            |||||            ......|....|.:::|||||.||||::|.|||||:|||||||..:::
plant    34 QIGGPGFSRVVYCNEPDSPEADSRNYSDNYVRTTKYTLATFLPKSLFEQFRRVANFYFLVTGVLA 98

  Fly   111 LLIDSPVSPMTSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNSSPVTVIR-DGKEAIIKSQDVIP 174
            ....:|.:..::::||:|||..|..|:|.||..|.:.||.||:..|.|.| ||.....:.:.:..
plant    99 FTPLAPYTASSAIVPLLFVIGATMVKEGVEDWRRQKQDNEVNNRKVKVHRGDGSFDAKEWKTLSI 163

  Fly   175 GELIVVERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLKT---LMVPRDLPTVDLPEMHKLG 236
            |:::.||::...|.|||||.|:.....|::.|.|||||:|||.   |.|...|    ..|.:..|
plant   164 GDIVKVEKNEFFPADLVLLSSSYEDAICYVETMNLDGETNLKVKQGLEVTSSL----RDEFNFKG 224

  Fly   237 ---IIECESPTTDLYSFNGKIELKGGEGRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQ 298
               .::||.|..:||||.|.:||||.:   .|||.:.:|||.|:::||:.:.|..::||..:|:.
plant   225 FEAFVKCEDPNANLYSFVGTMELKGAK---YPLSPQQLLLRDSKLRNTDFIFGAVIFTGHDTKVI 286

  Fly   299 LNSRLTRNKNASSETYINR--FLIVILVALIAIVTLLYF------------LKRY------NELF 343
            .||....:|.:..|..:::  :|:..:|..:|.:..:.|            :||:      :.:|
plant   287 QNSTDPPSKRSMIEKKMDKIIYLMFFMVITMAFIGSVIFGVTTRDDLKDGVMKRWYLRPDSSSIF 351

  Fly   344 VIPKLTYLGDATDSYSVKQFLQDYLSFLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENET 408
            ..||...:.          .:..:|:.::|::|.|||||||:||:.:|:.|.|:..|:.:|..|.
plant   352 FDPKRAPVA----------AIYHFLTAVMLYSYFIPISLYVSIEIVKVLQSIFINQDIHMYYEEA 406

  Fly   409 DQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMNFQQCSINGNKFLFKKTRLEDEETKALLDIN 473
            |:|....||||||||||::.:.||||||||.|.|.|.:||:.|..:....|.:|       :.:.
plant   407 DKPARARTSNLNEELGQVDTILSDKTGTLTCNSMEFIKCSVAGTAYGRGVTEVE-------MAMG 464

  Fly   474 KFSANQRVFFQALSICHTVQVASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQ 538
            :......||                  |:|......|            ||...||||
plant   465 RRKGGPLVF------------------QSDENDIDME------------YSKEAITEE------- 492

  Fly   539 SELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNG 603
                                 ||:            .|:               || |..|:.||
plant   493 ---------------------STV------------KGF---------------NF-RDERIMNG 508

  Fly   604 AASDLNINQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPN 668
                        |.||.                   :..|:.|.:
plant   509 ------------NWVTE-------------------THADVIQKF-------------------- 522

  Fly   669 AYLTNPVTASTPPAGVLFRSPSTTSRESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQAS 733
                             ||..:...             |::...:....|         :.|:|.
plant   523 -----------------FRLLAVCH-------------TVIPEVDEDTEK---------ISYEAE 548

  Fly   734 SPDEKALVEACANLGMVYTGDDDETLRVRIVPPHMDYKRPFAKPREETFQRLHVLEFTSDRKRMS 798
            ||||.|.|.|...||..:......|:.||    .:|...  .|..|..::.|:||||.|.|||||
plant   549 SPDEAAFVIAARELGFEFFNRTQTTISVR----ELDLVS--GKRVERLYKVLNVLEFNSTRKRMS 607

  Fly   799 VIVRDTDGKKWIYTKGAESYVFPLCANSSAELVTKTDAHISDFARLGLRTLAIARRLISEEEYQD 863
            |||::.|||..:..|||::.:|...:.:..|...:|..|::::|..|||||.:|.|.:.|:||:.
plant   608 VIVQEEDGKLLLLCKGADNVMFERLSKNGREFEEETRDHVNEYADAGLRTLILAYRELDEKEYKV 672

  Fly   864 FLVELAQANSSLE-NRKQLSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLT 927
            |...:::|.||:. :|:.|.||...|||.:|.|||||||||.||:.|.|.:..|..|||||||||
plant   673 FNERISEAKSSVSADRESLIEEVTEKIEKDLILLGATAVEDKLQNGVPDCIDKLAQAGIKIWVLT 737

  Fly   928 GDKVETALNIALSCGHIPPDAKKYFI------------------MECKNREEMLLHLNALDREII 974
            |||:|||:||..:|..:..|.|:..|                  :...::|.:|..:.....::.
plant   738 GDKMETAINIGFACSLLRQDMKQIIINLETPEIQSLEKTGEKDVIAKASKENVLSQIINGKTQLK 802

  Fly   975 FGIGQECALLIDGKSLGVALAEASSE-FRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTA 1038
            :..|...||:||||||..||.:.... |.::||.|.:|:|||.||.||:.|..|:||.| ...|.
plant   803 YSGGNAFALIIDGKSLAYALDDDIKHIFLELAVSCASVICCRSSPKQKALVTRLVKSGN-GKTTL 866

  Fly  1039 SIGDGANDVSMIQEAHVGIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYF 1103
            :||||||||.|:|||.:|:||.|.||.||...:|.|.|:|..|:||||||||:...|:|.::.||
plant   867 AIGDGANDVGMLQEADIGVGISGVEGMQAVMSSDIAIAQFRYLERLLLVHGHWCYRRISTMICYF 931

  Fly  1104 FYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRT---- 1164
            |||||.|...:||::.:|.|||:..|:..||:||||.::|||::.:.:.::..:....::.
plant   932 FYKNITFGFTLFLYETYTTFSSTPAYNDWFLSLYNVFFSSLPVIALGVFDQDVSARYCLKVNITT 996

  Fly  1165 ----------------------PQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFCFFYYN 1207
                                  |.||::...|....|...|.|:....|.:||||:  .|.....
plant   997 ALSSHQSKNLCQLLPFFLVLQFPLLYQEGVQNVLFSWRRILGWMFNGFYSAVIIFF--LCKSSLQ 1059

  Fly  1208 NVLLNY-GQTVAFSCFGTLLMWTVVVVVNLKLWLESMYLSF------------WYIFTIIISILG 1259
            :...|: |:|......|..:...:|.||||::.|...|.:.            ||.|..:...|.
plant  1060 SQAFNHDGKTPGREILGGTMYTCIVWVVNLQMALAISYFTLIQHIVIWSSIVVWYFFITVYGELP 1124

  Fly  1260 FVVTTVIYNVINLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQRALNIKSFSIF 1324
            ..::|..|.|.           ...|..||..||..:...||.|:|.:....||       .|.|
plant  1125 SRISTGAYKVF-----------VEALAPSLSYWLITLFVVVATLMPYFIYSALQ-------MSFF 1171

  Fly  1325 P 1325
            |
plant  1172 P 1172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	PhoLip_ATPase_N	57..121	CDD:292826	30/74 (41%)
		ATPase-Plipid	74..1317	CDD:273734	413/1328 (31%)
		E1-E2_ATPase	127..>345	CDD:278548	79/244 (32%)
		Cation_ATPase	<734..823	CDD:289987	36/88 (41%)
		HAD_like	<1036..1066	CDD:304363	19/29 (66%)
		PhoLip_ATPase_C	1068..1317	CDD:292829	81/287 (28%)
AT1G68710	NP_001320718.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3654
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920