DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4301 and AT3G13900

DIOPT Version :9

Sequence 1:	NP_573125.1	Gene:	CG4301 / 32610	FlyBaseID:	FBgn0030747	Length:	1342	Species:	Drosophila melanogaster
Sequence 2:	NP_188006.4	Gene:	AT3G13900 / 820603	AraportID:	AT3G13900	Length:	1243	Species:	Arabidopsis thaliana

Alignment Length:	1332	Identity:	406/1332 - (30%)
Similarity:	631/1332 - (47%)	Gaps:	267/1332 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 NRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVSPMTSLLPLVFVIAVTAAKQG 138
            |.:.:|:|.||||||:.|.|||.|:|||||||..|:|:...||.:..:.:.||:||:.::..|:.
plant    61 NYVSTTRYNLITFLPKCLYEQFHRVANFYFLVAAILSVFPLSPFNKWSMIAPLIFVVGLSMGKEA 125

  Fly   139 YEDILRYRTDNVVNSSPVTVIR-DGKEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKC 202
            .||..|:..|..|||...||.| ||.....|.:.:..|:::.||:|...|.||:||.|:...|.|
plant   126 LEDWRRFMQDVKVNSRKATVHRGDGDFGRRKWKKLRVGDVVKVEKDQFFPADLLLLSSSYEDGIC 190

  Fly   203 FITTANLDGESNLK-------TLMVPRDLPTVDLPEMHKLGIIECESPTTDLYSFNGKIELKGGE 260
            ::.|.|||||:|||       ||.:.||    |..:... |.|:||.|..:||:|.|.:|.   :
plant   191 YVETMNLDGETNLKVKRCLDVTLPLERD----DTFQSFS-GTIKCEDPNPNLYTFVGNLEY---D 247

  Fly   261 GRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINRFLIVILVA 325
            |:|.||....:|||.|:::||..|.|..|:||..:|:..||    .|:.|..:.|.:.:..|:..
plant   248 GQVYPLDPSQILLRDSKLRNTSYVYGVVVFTGHDTKVMQNS----TKSPSKRSRIEKRMDYIIYT 308

  Fly   326 LIAIVTLLYFLKRYNELFVIPKLTYLGD------------ATDSYSVKQFLQDYLSFLILFNYLI 378
            |.|::.|:.|:....  |.:....::||            .........::...::.::|:.|||
plant   309 LFALLVLVSFISSLG--FAVMTKMHMGDWWYLRPDKPERLTNPRNPFHAWVVHLITAVLLYGYLI 371

  Fly   379 PISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMN 443
            ||||||:|||.:|:.:.|:..||::|::|:..|....||||||||||::.:.||||||||.|:|:
plant   372 PISLYVSIELVKVLQATFINQDLQMYDSESGTPAQARTSNLNEELGQVDTILSDKTGTLTCNQMD 436

  Fly   444 FQQCSINGNKFLFKKTRLEDEETKAL-LDINKFSANQRVFFQALSICHTVQVASGSLEQADAGTA 507
            |.:|||.|..:..:.:.:|....|.: :|:::                         ||.
plant   437 FLKCSIAGTSYGVRASEVELAAAKQMAIDLDE-------------------------EQG----- 471

  Fly   508 KREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLV 572
              |.||.:......|:..:.:..::   |...||                  .|:|::
plant   472 --EEVTHLPRTRGRMHGYAKMPSKT---SSDIEL------------------ETVITA------- 506

  Fly   573 SDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFRPISLQFRR 637
            :|:|                                  :||.          :|..:..|.:.:|
plant   507 TDEG----------------------------------DQTQ----------STGIKGFSFEDQR 527

  Fly   638 STSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSRESYAAPTF 702
            ......|.:                    ||:            ..:|.               |
plant   528 LMGGNWLNE--------------------PNS------------DDILM---------------F 545

  Fly   703 TRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIVPPH 767
            .|     :.|.......|:.:......|:|.||||.|.:.|....|..:|.....::.:.
plant   546 LR-----ILAVCHTAIPEVDEDTGKCTYEAESPDEVAFLVAAGEFGFEFTKRTQSSVFIS----- 600

  Fly   768 MDYKRPFAKPREETFQRLHVLEFTSDRKRMSVIVRDTDGKKWIYTKGAESYVFPLCANSSAELVT 832
               :|...:|.|..::.|:||:|||.||||||||||..|:..:..|||:|.:|...:.:....:.
plant   601 ---ERHSGQPVEREYKVLNVLDFTSKRKRMSVIVRDEKGQILLLCKGADSIIFERLSKNGKNYLE 662

  Fly   833 KTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSL-ENRKQLSEECYAKIESNLDLL 896
            .|..|::.:...||||||::.|.:.|.||..:..|..:|.:|: .:|.::.|:....:|..|.|:
plant   663 ATSKHLNGYGEAGLRTLALSYRKLDETEYSIWNSEFHKAKTSVGADRDEMLEKVSDMMEKELILV 727

  Fly   897 GATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAKKYFIM------- 954
            |||||||.||..|...:..|..||:|||||||||:|||:||..:|..:....|:.:|.
plant   728 GATAVEDKLQKGVPQCIDKLAQAGLKIWVLTGDKMETAINIGYACSLLRQGMKQIYIALRNEEGS 792

  Fly   955 ----ECKNREEMLLH-LNA-------LDREIIFGIGQECALLIDGKSLGVALA-EASSEFRDVAV 1006
                |...||.:|:. :||       .|....|      ||:||||:|..||. :...:|..:||
plant   793 SQDPEAAARENILMQIINASQMIKLEKDPHAAF------ALIIDGKTLTYALEDDIKYQFLALAV 851

  Fly  1007 KCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCA 1071
            .|.:|:|||:||.||:.|..|.|... ...|.:||||||||.|||||.:|:||.|.||.||...:
plant   852 DCASVICCRVSPKQKALVTRLAKEGT-GKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMAS 915

  Fly  1072 DFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTL 1136
            ||:.|:|..|:|||:||||:...|::.::.|||||||.|...:|.|:..|.||..::|:..:|.|
plant   916 DFSIAQFRFLERLLVVHGHWCYKRIAQMICYFFYKNITFGLTLFYFEAFTGFSGQAIYNDSYLLL 980

  Fly  1137 YNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAF 1201
            :|||.||||::.:.:.|:..:.|..::.|.||::...|....|...:.|:...:|.||:||....
plant   981 FNVILTSLPVIALGVFEQDVSSEVCLQFPALYQQGPKNLFFDWYRIIGWMANGVYASVVIFSLNI 1045

  Fly  1202 CFFYYNNVLLNYGQTVAFSCFGTLLMWTVVVVVNLKL--------WLESMY----LSFWYIFTII 1254
            ..|:..: ..:.|||......||.:...::..||:::        |::.:.    :..||||
plant  1046 GIFHVQS-FCSGGQTADMDAMGTAMFTCIIWAVNVQIALTMSHFTWIQHVLIWGSIVTWYIF--- 1106

  Fly  1255 ISILGFVVTTVIYNVINLDYDTDIYWAYNNLLASLPV-WLWIIVTCVACLVPDYTIRMLQRALN- 1317
            :::.|.:...|..|:.::..:|         ||..|: ||..::...|..:|.......||:||
plant  1107 LALFGMLPPKVSGNIFHMLSET---------LAPAPIFWLTSLLVIAATTLPYLAYISFQRSLNP 1162

  Fly  1318 --------IKSFSI-----FPGKQRKLKMREK 1336
                    ||.|.|     ....:.:.|.|||
plant  1163 LDHHIIQEIKHFRIDVQDECMWTRERSKAREK 1194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	PhoLip_ATPase_N	57..121	CDD:292826	25/46 (54%)
		ATPase-Plipid	74..1317	CDD:273734	396/1297 (31%)
		E1-E2_ATPase	127..>345	CDD:278548	79/225 (35%)
		Cation_ATPase	<734..823	CDD:289987	33/88 (38%)
		HAD_like	<1036..1066	CDD:304363	20/29 (69%)
		PhoLip_ATPase_C	1068..1317	CDD:292829	75/261 (29%)
AT3G13900	NP_188006.4	ATPase-Plipid	58..1170	CDD:273734	398/1306 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3654
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920