Protein Alignment CG4301 and Atp9b

DIOPT Version :10

• Sequence 1: NP_573125.1
• Gene: CG4301 / 32610
• FlyBaseID: FBgn0030747
• Length: 1342
• Species: Drosophila melanogaster
• Sequence 2: XP_017456363.1
• Gene: Atp9b / 291411
• RGDID: 1563006
• Length: 1158
• Species: Rattus norvegicus
• Alignment Length: 1333
• Identity: 357/1333 - (26%)
• Similarity: 550/1333 - (41%)
• Gaps: 342/1333 - (25%)

  Fly    53 DWL-------------QIQIGGPQDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFL 104
            |||             .:.:|.|:..::|.|:  |.||:.||.:.||:|..|.|||:...|.|||
  Rat   101 DWLINVCQRKKELKARTVWLGCPEKCEEKHPR--NSIKNQKYNVFTFIPGVLYEQFKFFLNLYFL 163

  Fly   105 VMTIISLLIDSPVSPM-TSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNS---SPVTVIRDGKEA 165
            |::....:....:..: |...||.||:|||.|::..::..|::.|..:||   |.:||  .|| .
  Rat   164 VVSCSQFVPALKIGYLYTYWAPLGFVMAVTIAREAIDEFRRFQRDKEMNSQLYSKLTV--RGK-V 225

  Fly   166 IIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLKTLMVPRDLPTVDLP 230
            .:||.|:..|:||:||::..:|.|:|.||:::..|.|||.|..||||::.| |.|.... |..||
  Rat   226 QVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWK-LKVAVSC-TQRLP 288

  Fly   231 EMHKL----GIIECESPTTDLYSFNGKIELKGGEGRV-LPLSTENVLLRGSRVKNTECVIGCAVY 290
            .:..|    ..:..:.|..|::||.|.......:..: ..||.||.|. .|.:..:..|||..:|
  Rat   289 ALGDLFSISAYVYAQKPQLDIHSFEGTFTRDDSDPPIHESLSIENTLW-ASTIVASGTVIGVVIY 352

  Fly   291 TGMISKLQLNSRLTRNKNASSETYINRFLIVILVALIAIVTLLYFLKRYNELFVIPKLTYLGDAT 355
            ||..::..:|:...:||....:..:|:....:.:||:.:..::              :|..|.|.
  Rat   353 TGKETRSVMNTSNPKNKVGLLDLELNQLTKALFLALVVLSVVM--------------VTLQGFAG 403

  Fly   356 DSYSVKQFLQDYLSFLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLN 420
            ..|      ::...||:||:|:|||||.|.:::.:....|.      :.::|.....||.||.:.
  Rat   404 PWY------RNLFRFLLLFSYIIPISLRVNLDMGKAAYGWM------IMKDENIPGTVVRTSTIP 456

  Fly   421 EELGQINILFSDKT-----------GTLTKNEMNFQQCSINGNKFLFKKTRLEDEETKALLDINK 474
            ||||::..|.:|||           .|||:|||            :||:..|
  Rat   457 EELGRLVYLLTDKTVTKAKALYSPARTLTQNEM------------VFKRLHL------------- 496

  Fly   475 FSANQRVFFQALSICHTVQVASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQS 539
                                          ||.                        |:......
  Rat   497 ------------------------------GTV------------------------SYGTDTMD 507

  Fly   540 ELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGA 604
            |:. .|.:::.:..|
  Rat   508 EIQ-SHVLNSYLQVH-------------------------------------------------- 521

  Fly   605 ASDLNINQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNA 669
                              ..|:...|.|...|||.|
  Rat   522 ------------------SQTSGHNPSSAPLRRSQS----------------------------- 539

  Fly   670 YLTNPVTASTPPAGVLFRSPSTTSRESYAA--------PTFTRQPTILVRAESQRRKNEIRDFIF 726
                    |||.   :.:|.|:...|:..|        |.:..:..|....|......:..|...
  Rat   540 --------STPK---VKKSVSSRIHEAVKAIALCHNVTPVYEARTGITGETEFAEADQDFSDENR 593

  Fly   727 TLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIVPPHMDYKRPFAKPREETFQRLHVLEFT 791
            |  ||||||||.|||....::|:.....|..:         |..|.|..:..  |:..|.:..||
  Rat   594 T--YQASSPDEVALVRWTESVGLTLVSRDLAS---------MQLKTPSGQVL--TYCILQMFPFT 645

  Fly   792 SDRKRMSVIVRD-TDGKKWIYTKGAESYVFPLCANSSAELVTKTDAHISDFARLGLRTLAIARRL 855
            |:.|||.:|||| ...:...|.|||:     :..::..:.....:....:.||.|||||.:|:|.
  Rat   646 SESKRMGIIVRDEATAEITFYMKGAD-----VAMSTIVQYNDWLEEECGNMAREGLRTLVVAKRT 705

  Fly   856 ISEEEYQDFLVELAQANSSLENRKQLSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAG 920
            ::||:||||....:||..|:.:|..........:|..::||..|.|||.||.||..||..|:.||
  Rat   706 LTEEQYQDFESRYSQAKLSIHDRTLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAG 770

  Fly   921 IKIWVLTGDKVETALNIALSCGHIPPDAKKYFIMECKNREEMLLHLNALDREIIFGIGQECALLI 985
            ||||:|||||:|||..||.|...:......:......||.|..|.|||..|:      .:|||:|
  Rat   771 IKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRPVTNRGEAHLELNAFRRK------HDCALVI 829

  Fly   986 DGKSLGVALAEASSEFRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMI 1050
            .|.||.|.|.....|..::|.:|.||:|||.||.||:.:|:|::..... .|.:||||.||||||
  Rat   830 SGDSLEVCLRYYEHELVELACQCPAVVCCRCSPTQKAHIVTLLRQHTRK-RTCAIGDGGNDVSMI 893

  Fly  1051 QEAHVGIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMF 1115
            |.|..||||.|:||:||:..|||:..:|..:.|||:|||.....|.:.|..:..::.::...:..
  Rat   894 QAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQA 958

  Fly  1116 LFQFHTLFSSSSVYDSLFLTLYNVIYTSLPILFIAISE--KPYTEEKLMRTPQLYKKNTDNKQLH 1178
            :|.....|:|..:|....:..|..|||..|:..:.:.:  ||   |..:..|:|||..|..:.|.
  Rat   959 VFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKP---EMAILYPELYKDLTKGRSLS 1020

  Fly  1179 WPYFLMWVLFAIYHSVIIFYFAFCFFYYNNVLLNYGQTVAFSCFGTLLMWTVVVVVNLKLWLESM 1243
            :..||:|||.:||...|:.|.|...|.     ..:...||.|....:|...::|.:.::.|...|
  Rat  1021 FKTFLIWVLISIYQGGILMYGALLLFE-----AEFVHVVAISFTALILTELLMVALTIRTWHWLM 1080

  Fly  1244 YLSFWYIFTIIISILGFV-------------------VTTVIYNVINLDYDTDIYWAYNNLLASL 1289
            .::.:......::.|.|:                   :|||.:
  Rat  1081 VVAEFLSLGCYVASLAFLNEYFGIGRVSFGAFLDVAFITTVTF---------------------- 1123

  Fly  1290 PVWLWIIVTCVACLVPDYTIRMLQRALNIKSFS 1322
             :|....:|.|:|| |.|.::.|:|.|:..|:|
  Rat  1124 -LWKVSAITVVSCL-PLYVLKYLKRKLSPPSYS 1154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	Haloacid Dehalogenase-like Hydrolases	74..1317	CDD:473868	347/1292 (27%)
Atp9b	XP_017456363.1	P-type_ATPase_APLT_Neo1-like	132..1067	CDD:319841	330/1189 (28%)
		Cation_ATPase	560..671	CDD:463817	36/123 (29%)