Protein Alignment CG4301 and tat-6

DIOPT Version :9

• Sequence 1: NP_573125.1
• Gene: CG4301 / 32610
• FlyBaseID: FBgn0030747
• Length: 1342
• Species: Drosophila melanogaster
• Sequence 2: NP_503858.1
• Gene: tat-6 / 178754
• WormBaseID: WBGene00017174
• Length: 1064
• Species: Caenorhabditis elegans
• Alignment Length: 1312
• Identity: 344/1312 - (26%)
• Similarity: 545/1312 - (41%)
• Gaps: 374/1312 - (28%)

  Fly    57 IQIG-GPQDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVSPM 120
            ::|| ||.|....|....|.:::.||.:.:|:|..|.::|:...|.|||:|....|:   |:..:
 Worm    78 VRIGYGPIDHDSPRTFPPNTVRNQKYNIFSFVPVVLFQEFKFFLNLYFLIMAFSQLV---PIFKI 139

  Fly   121 TSLL----PLVFVIAVTAAKQGYEDILRYRTDNVVNSSPV-TVIRDGKEAIIKSQDVIPGELIVV 180
            .:|:    ||.|::.:|..::..||..|:..|..:||... .:.|||....|||.|:..|::||:
 Worm   140 GALVTYWFPLGFILTITLIREAIEDFARFLRDRELNSEKYEKLTRDGTRVEIKSADIKVGDVIVM 204

  Fly   181 ERDCDVPCDLVLLRSTDPHGKCFITTANLDGESNLKTLMVPRDLP-TVDLPEMHKLGIIEC---- 240
            .:|..||.|:||||::|....|||.|..||||::.| |.:|  :| |..|....::..:.|
 Worm   205 HKDRRVPADVVLLRTSDKSSSCFIRTDQLDGETDWK-LKIP--IPFTQHLANESEIMELNCEVYA 266

  Fly   241 ESPTTDLYSFNGKIEL----KGGEGRVLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNS 301
            |.|..|:|||.|.:::    |..||   .|..||||. .:.|.::...||..||||..::..:|:
 Worm   267 EKPQKDIYSFVGTVKITADDKIHEG---SLDVENVLW-ANTVVSSGTAIGVVVYTGCETRSVMNT 327

  Fly   302 RLTRNKNASSETYINR-----FLIVILVALIAIV----TLLYFLKRYNELFVIPKLTYLGDATDS 357
            .:...|....:..||.     |..|:|:|.:.::    |.|::|
 Worm   328 TVPEYKVGLLDLEINNLTKLLFCFVLLLASVMVLMKGPTSLWYL--------------------- 371

  Fly   358 YSVKQFLQDYLS-FLILFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNE 421
                     ||: |::||:|:|||||...:::.::..||.:..|..:.|.      ||.:|.:.|
 Worm   372 ---------YLARFILLFSYIIPISLRTNVDMAKLFYSWQIGHDHHIPET------VVRSSTIPE 421

  Fly   422 ELGQINILFSDKTGTLTKNEMNFQQCSINGNKFLFKKTRLEDEETKALLDINKFSANQRVFFQAL 486
            |||:|:.|.||||||||||||:|::..:.
 Worm   422 ELGRISFLLSDKTGTLTKNEMHFKKIHLG------------------------------------ 450

  Fly   487 SICHTVQVASGSLEQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSV 551
                ||..:..:||:.                                     |.:|....|:::
 Worm   451 ----TVAFSGDALEEV-------------------------------------EQHVKSAYDSAL 474

  Fly   552 SAHP------NGVNSTIISSDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNI 610
            ..||      |.|.|..:..:|.|:|                             .||
 Worm   475 VKHPFSAKLKNAVESLALCHNVTPVL-----------------------------ENG------- 503

  Fly   611 NQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPV 675
                                                                             
 Worm   504 ----------------------------------------------------------------- 503

  Fly   676 TASTPPAGVLFRSPSTTSRESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKAL 740
                                                               .|.|||:||||.||
 Worm   504 ---------------------------------------------------ELSYQAASPDEVAL 517

  Fly   741 VEACANLGMVYTGDDDETLRVRIVPPHMDYKRPFAKPREET-----FQRLHVLEFTSDRKRMSVI 800
            |:....:|:.....|..|:.:.:            :|...|     ||.|||..|||:||||.:|
 Worm   518 VKWTETVGVKLAHRDLHTMTLDV------------QPSNGTTVPIQFQILHVFPFTSERKRMGII 570

  Fly   801 VR-DTDGKKWIYTKGAESYVFPLCANSSAELVTKT---DAHISDFARLGLRTLAIARRLISEEEY 861
            |: :|.|:..:|.|||::.:        :::|...   |...::.||.|||||..|::::|..|.
 Worm   571 VKEETSGEVTLYIKGADTVM--------SDMVQYNDWLDEECTNMAREGLRTLVFAKKILSRAEL 627

  Fly   862 QDFLVELAQANSSLENRKQ-LSEECYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWV 925
            :.|......|..|:.||.| ::......:|.:|.|:..|.|||.|||.|..:|..|:.||||||:
 Worm   628 EAFDQAYHAAKMSITNRTQNMANVVKNMLERDLQLICLTGVEDRLQDQVTTSLELLRNAGIKIWM 692

  Fly   926 LTGDKVETALNIALSCGHIPPDAKKYFIMECKNREEMLLHLNALDREIIFGIGQECALLIDGKSL 990
            |||||:|||:.||.|.|........:.....:.|.:....|:.|..:      ...||::.|.||
 Worm   693 LTGDKLETAICIAKSSGLFSKSDHIHVFGSVQTRTDAYNELDNLRNK------TNIALVMPGSSL 751

  Fly   991 GVALAEASSEFRDVAVKCTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHV 1055
            .:.|.....|..::....|||:|||.||.||:::|.|::........|:||||.|||||||.||.
 Worm   752 NICLQYYEEEVAELVCASTAVVCCRCSPEQKAQIVQLLRKYRAPLRVAAIGDGGNDVSMIQAAHA 816

  Fly  1056 GIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFH 1120
            ||||...||:||:..|||:..:|..:.|||||||.:...|...|..:..::.::...:..:|...
 Worm   817 GIGIDANEGKQASLAADFSITQFSHICRLLLVHGRFSYKRSCTLAQFIMHRGLLISIVQAIFSCV 881

  Fly  1121 TLFSSSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMW 1185
            ..|.:.|:|..:.:..:...||.||: |..|:::..|....:..|:|||:....:.|.:..|.:|
 Worm   882 FYFVAVSLYQGVLMVAFTSCYTLLPV-FSLIADRDVTATNALTYPELYKELVKGRTLSYKTFFIW 945

  Fly  1186 VLFAIYHSVIIFYFAFCFFYYNNVLLNYGQTVAFSCFGTLLMWTVVVVVNLKLWLESMYLSFWYI 1250
            |..:||...:|.|.|...|  :..:|:. .:::||.    |:.|.:::|.|     :::...|.:
 Worm   946 VFISIYQGAVIMYGALLIF--DTDILHI-VSISFSA----LIATELIMVAL-----TVHTWHWLM 998

  Fly  1251 FTIIISILGFVVTTVIYNVINLDYDTDIYWAYNNLLASLPVWLWIIVT-----CVACLVPDYTIR 1310
            .......||..|.    ::|.||...|..:.::          |:.:|     .|...:|.|.|:
 Worm   999 LVAQALSLGLYVV----SLITLDQFFDRKFVFS----------WVFITKTTAITVVSSLPLYFIK 1049

  Fly  1311 MLQRALNIKSFS 1322
            .|:|..:..||:
 Worm  1050 TLRRKFSPPSFA 1061

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	PhoLip_ATPase_N	57..121	CDD:292826	20/64 (31%)
		ATPase-Plipid	74..1317	CDD:273734	336/1287 (26%)
		E1-E2_ATPase	127..>345	CDD:278548	75/236 (32%)
		Cation_ATPase	<734..823	CDD:289987	32/94 (34%)
		HAD_like	<1036..1066	CDD:304363	20/29 (69%)
		PhoLip_ATPase_C	1068..1317	CDD:292829	61/253 (24%)
tat-6	NP_503858.1	PhoLip_ATPase_N	86..144	CDD:292826	17/60 (28%)
		ATPase-Plipid	93..1063	CDD:273734	338/1297 (26%)
		E1-E2_ATPase	151..388	CDD:278548	84/273 (31%)
		Cation_ATPase	492..590	CDD:289987	41/261 (16%)
		HAD_like	<782..824	CDD:304363	21/41 (51%)
		PhoLip_ATPase_C	829..1057	CDD:292829	61/254 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920