Protein Alignment CG4301 and tat-1

DIOPT Version :9

• Sequence 1: NP_573125.1
• Gene: CG4301 / 32610
• FlyBaseID: FBgn0030747
• Length: 1342
• Species: Drosophila melanogaster
• Sequence 2: NP_001255165.1
• Gene: tat-1 / 176666
• WormBaseID: WBGene00013034
• Length: 1192
• Species: Caenorhabditis elegans
• Alignment Length: 1300
• Identity: 379/1300 - (29%)
• Similarity: 573/1300 - (44%)
• Gaps: 355/1300 - (27%)

  Fly    74 NRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLID-SPVSPMTSLLPLVFVIAVTAAKQ 137
            |||.:.||...:|||:.|.|||||..|.:||.:.::..:.| ||....|:.:|.:.:::|:|.|:
 Worm    31 NRISTCKYNGFSFLPRFLYEQFRRYNNIFFLAIALLQQIPDVSPTGRYTTAVPFLIILSVSALKE 95

  Fly   138 GYEDILRYRTDNVVNSSPVTVIRDGKEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKC 202
            .:||:.|.|:||.||:..|.::.||.....:.:||..|:.|.::.|...|.||:||.|::..|..
 Worm    96 IFEDVKRRRSDNKVNAFSVEILVDGHWIEKQWKDVSVGDFIRIDNDSLFPADLLLLASSEQQGMA 160

  Fly   203 FITTANLDGESNLKTLMVPRDLPTVDLPEMHKLGIIE----CESPTTDLYSFNGKIELKGGEGRV 263
            :|.|:|||||:|||.........|:..||  ||...|    ||.|:..:..|||.||:.|....
 Worm   161 YIETSNLDGETNLKIKQALDITSTMTSPE--KLSQFESEITCEPPSRHVNEFNGNIEINGVARH- 222

  Fly   264 LPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINR---FLIVILVA 325
              ...:.:||||:|:|||..:.|..:|||..|||.:||:....|:.:.:...|.   ||..:|||
 Worm   223 --FGIDQLLLRGARLKNTAWIFGAVIYTGHDSKLLMNSKRAPLKSGTIDVQTNYRIIFLFFVLVA 285

  Fly   326 LIAIVTLLYFLKRYNELFVIPKLTYLG----DATDSYSVKQFLQDYLSFLILFNYLIPISLYVTI 386
            |..|......:.|.|.   ||:..||.    |...|     ||...|:|.||:|.||||||.||:
 Worm   286 LALISATGSEIWRGNN---IPQAWYLSFLEHDPKGS-----FLWGVLTFFILYNNLIPISLQVTL 342

  Fly   387 ELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMNFQQCSING 451
            |:.|...:.::..|:|:|:..:|...:..||||||||||:..:.||||||||:|.|.|::.||..
 Worm   343 EVVRFFQAIYINNDIEMYDVNSDSCAIARTSNLNEELGQVKFIMSDKTGTLTRNVMKFKRLSIGS 407

  Fly   452 NKF------------LFKKTRLEDEETKALLDINKFSANQRVFFQALSICHTVQVASGSLEQADA 504
            ..:            |.:..|..||.:.::|::.|.          :::||||
 Worm   408 RNYGNNEDDEFADASLIEDYRQGDEHSTSILEVLKM----------MAVCHTV------------ 450

  Fly   505 GTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDVNP 569
                          .||
 Worm   451 --------------VPE------------------------------------------------ 453

  Fly   570 LLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFRPISLQ 634
                                                                             
 Worm   454 ----------------------------------------------------------------- 453

  Fly   635 FRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSRESYAA 699
                  .||         ||
 Worm   454 ------NKD---------GQ--------------------------------------------- 458

  Fly   700 PTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIV 764
                                        |.||:|||||.|||...|:          :::.....
 Worm   459 ----------------------------LIYQSSSPDEAALVRGAAS----------QSVSFHTR 485

  Fly   765 PPHMDYKRPFAKPREETFQRLHVLEFTSDRKRMSVIVRD-TDGKKWIYTKGAESYVFPLC--ANS 826
            .|.......|.:  :||.:.|.|::|||||||||||||| ..|...:|||||::.:|...  ...
 Worm   486 QPQKVICNVFGE--DETIEILDVIDFTSDRKRMSVIVRDGAGGDIKLYTKGADTVIFERLEHGKE 548

  Fly   827 SAELVTKTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEECYAKIES 891
            ..|.|.....|:.|:|..|.|||..:.|.::|:||..:..|..:|..:::||.:|..:...|:|.
 Worm   549 QEEAVEYCTEHLEDYASFGYRTLCFSMRHLTEQEYSQWAPEYKKAILAIDNRAKLLADAAEKLER 613

  Fly   892 NLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAKKYFIMEC 956
            |:.|:||||:||.||:.|.:|:.:|.||.|::|:|||||.|||:|||.||.            .|
 Worm   614 NMILVGATAIEDKLQEWVPETIQALMAADIRVWMLTGDKRETAINIAHSCA------------LC 666

  Fly   957 KNREEMLL--------HLNALDREIIFGIGQE-----CALLIDGKSLGVAL-AEASSEFRDVAVK 1007
            ....|:|:        ....|::.:...|..|     .|::||||||..|| .||...|.|:|::
 Worm   667 HTNTELLIVDKTTYEETYQKLEQFVARAIELEKQEKGFAMVIDGKSLLHALTGEARKHFGDLALR 731

  Fly  1008 CTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCAD 1072
            |.||:|||:||:||:|||.:::...::. ..:||||||||:|||.|:||:||.|.||.|||..:|
 Worm   732 CHAVVCCRMSPMQKAEVVEMVRKLAKHV-VLAIGDGANDVAMIQAANVGVGISGEEGLQAASASD 795

  Fly  1073 FAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLY 1137
            :|..:|..|:|||||||.::..|...::||.|||||....|...|...:.:|..::::...:.::
 Worm   796 YAIPRFHFLRRLLLVHGAWNHDRSVKVILYSFYKNICLYIIELWFAMFSAWSGQTIFERWTIGMF 860

  Fly  1138 NVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFC 1202
            |||:|:.|.:.:.:.:.|...|::|:.|.|| .:..|:......|.:|:..||.||:.:|:..:.
 Worm   861 NVIFTAWPPVVLGLFDHPVPAEQIMKYPALY-ASFQNRAFSIGNFSLWIGLAIVHSLSLFFLTYA 924

  Fly  1203 FFYYNNVLLN-------------YGQTVAFSCFGTLL---MWTVVVVV----NLKLWLESMYLSF 1247
            ...:..|..|             |...||..||..||   .||..|||    ::.||     :.|
 Worm   925 TMEHQVVWDNGLTGGWLMLGNCAYTFVVATVCFKALLECDSWTWPVVVACIGSIGLW-----IVF 984

  Fly  1248 WYIFTIIISILGFVVTTVIYNVINLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRML 1312
            ..:::::...:|.:             ..|:......:::|...||.::...:|.|:.|..|:.|
 Worm   985 VIVYSLVFPHIGGI-------------GADMAGMAAIMMSSYTFWLALLFIPLATLLWDLVIKSL 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	PhoLip_ATPase_N	57..121	CDD:292826	20/47 (43%)
		ATPase-Plipid	74..1317	CDD:273734	378/1299 (29%)
		E1-E2_ATPase	127..>345	CDD:278548	79/224 (35%)
		Cation_ATPase	<734..823	CDD:289987	35/89 (39%)
		HAD_like	<1036..1066	CDD:304363	19/29 (66%)
		PhoLip_ATPase_C	1068..1317	CDD:292829	68/264 (26%)
tat-1	NP_001255165.1	PhoLip_ATPase_N	16..79	CDD:292826	20/47 (43%)
		ATPase-Plipid	28..1036	CDD:273734	378/1298 (29%)
		E1-E2_ATPase	85..>178	CDD:278548	36/92 (39%)
		Cation_ATPase	446..545	CDD:289987	49/337 (15%)
		HAD_like	<745..789	CDD:304363	23/44 (52%)
		PhoLip_ATPase_C	791..1043	CDD:292829	68/264 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920