Protein Alignment CG4301 and atp11c

DIOPT Version :10

• Sequence 1: NP_573125.1
• Gene: CG4301 / 32610
• FlyBaseID: FBgn0030747
• Length: 1342
• Species: Drosophila melanogaster
• Sequence 2: XP_004917005.2
• Gene: atp11c / 100498300
• XenbaseID: XB-GENE-976439
• Length: 1149
• Species: Xenopus tropicalis
• Alignment Length: 1354
• Identity: 435/1354 - (32%)
• Similarity: 667/1354 - (49%)
• Gaps: 317/1354 - (23%)

  Fly    17 RLGAHRQTPWADQESFHLKDAFLWNWHKGSRVSTINDWLQIQIGGPQDIKKK----RPK-GQNRI 76
            |||..|..|..:                 :||.|...::     ||:...:.    :|| ..|||
 Frog     3 RLGCSRLCPGEE-----------------NRVGTRTVYV-----GPRSASETDAYIQPKFCDNRI 45

  Fly    77 KSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVSPMTSLLPLVFVIAVTAAKQGYED 141
            .|:|||:..|:|:||.||||||||||||::.:|..::|:|.||:||.|||.|||.|||.||||||
 Frog    46 VSSKYTIWNFIPKNLFEQFRRIANFYFLIIFLIQAIVDTPTSPVTSGLPLFFVITVTAIKQGYED 110

  Fly   142 ILRYRTDNVVNSSPVTVIRDGKEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKCFITT 206
            .||:|.|:.||.|.|.||...|....:|:.:..|:::.|..:...|||||:|.::...|.|.:||
 Frog   111 WLRHRADHEVNKSTVYVIEGSKCVKKESEKIKVGDIVEVRDNETFPCDLVMLSTSCRDGTCTVTT 175

  Fly   207 ANLDGESNLKTL-MVPRDLPTVDLPEMHKL-GIIECESPTTDLYSFNGKIELKGGEG-RVLPLST 268
            |:||||||.||. .||.........:::.. ..||||.|..|||.|:|:|::...:. :...|..
 Frog   176 ASLDGESNFKTYHAVPETAILATYEDLNAFSATIECEQPQPDLYKFHGRIDVNTNQDVKARSLGP 240

  Fly   269 ENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINRFLIVILVALIAIVTLL 333
            ||:||:|:.:|||:.:.|.||||||.:|:.||.:....|.::.|..||.||||.|..|::..|:.
 Frog   241 ENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLCILVSKATIC 305

  Fly   334 YFLKR------------YNELFVIPKLTYLGDATDSYSVKQFLQDYLSFLILFNYLIPISLYVTI 386
            ..||.            |||.....|        :::.:.:...|:|||::|||::||:|:|||:
 Frog   306 TSLKYLWQSNPANDEPWYNEKTRKEK--------EAFKILKMFTDFLSFMVLFNFIIPVSMYVTV 362

  Fly   387 ELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNEMNFQQCSING 451
            |:|:.:||:|:.||:|:::.|.::..:||||:|||||||:..:|:|||||||:|:|.|.:|.|:|
 Frog   363 EMQKFLGSFFIAWDMEMFDEEINEGALVNTSDLNEELGQVEYVFTDKTGTLTENKMEFIECCIDG 427

  Fly   452 NKFLFKKTRLED--EETKALLDINKFSAN-QRVFFQALSICHTVQVASGSLEQADAGTAKREPVT 513
            :|  :..|...|  ..|..|....|.|.: :.:|.:||.:|||||
 Frog   428 HK--YANTDAMDGLSLTDGLAYFGKASQDLEELFLRALCLCHTVQ-------------------- 470

  Fly   514 AIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDVNPLLVSDDGYG 578
                          :.||.|
 Frog   471 --------------MKEECH--------------------------------------------- 476

  Fly   579 VERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFRPISLQFRRSTSEKD 643
                                                    |:|
 Frog   477 ----------------------------------------TDG---------------------- 479

  Fly   644 LQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSRESYAAPTFTRQPTI 708
                                                         ||.:|.::.|
 Frog   480 ---------------------------------------------PSFSSTDNCA---------- 489

  Fly   709 LVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETLRVRIVPPHMDYKRP 773
                                 |.:|||||.|||......|..|.|.::..:.|.
 Frog   490 ---------------------YISSSPDEIALVTGAKRYGFTYMGTENNVMSVE----------- 522

  Fly   774 FAKPREETFQRLHVLEFTSDRKRMSVIVRDTDGKKWIYTKGAESYVFPLCANSSAELVTKTDAHI 838
            ..|...|.:|.||||.|...|:||||:|:...||.:::.|||:|.:||..|.   :.|.:...|:
 Frog   523 NQKNEIERYQLLHVLNFDPVRRRMSVLVKAKTGKIFLFCKGADSSMFPRVAR---DQVQRIKVHV 584

  Fly   839 SDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEECYAKIESNLDLLGATAVED 903
            ...|..|.|||.:|.:.:|:|.|::...:|.:|..:|::|::...:.|..||:::.|||||||||
 Frog   585 EKNALDGYRTLCVAFKEVSQELYENINKQLEEAKLALQDREERLAKVYDDIEADMHLLGATAVED 649

  Fly   904 ALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHI----------PPDAKKYFIMECKN 958
            .||:..|:|:.:|.|||:|:|||||||:|||.:...:|...          ..|.::|...|.:.
 Frog   650 RLQEQAAETIEALHAAGMKVWVLTGDKLETAKSTCYACRLFQSNTELLELTTKDLEEYERKEDRL 714

  Fly   959 REEMLLHLNALDREI---------IFGIGQECALLIDGKSLGVALAE--ASSEFRDVAV----KC 1008
            :|.::.:...|.:|.         .:...|:..|:|||.:|.:.|..  :||.::::.:    ||
 Frog   715 QELLMEYHRKLVQEAPKLKGGANRSWTGNQDHGLIIDGATLSLILNSNCSSSHYKNIFLQICQKC 779

  Fly  1009 TAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCADF 1073
            :||||||::||||:::|.::|::..:..|.|:||||||||||.||||||||.|:|||||||.:|:
 Frog   780 SAVLCCRMAPLQKAQIVKMVKNTKGSPITLSVGDGANDVSMILEAHVGIGIKGKEGRQAARSSDY 844

  Fly  1074 AFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLYN 1138
            |..||..|::|||.|||.:.||::.||.||||||:.|:...||:||...||...:||:.:||:||
 Frog   845 AVPKFKHLRKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYN 909

  Fly  1139 VIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFCF 1203
            :.:||:|||..::.|:....|.|...|:||.:.:||..|.|..||.|.|...:.. ::|:|...|
 Frog   910 ICFTSMPILAYSLLEQRINIEILSSNPKLYMRISDNAMLQWGPFLYWTLLGAFEG-LVFFFGVYF 973

  Fly  1204 FYYNNVLLNYGQTVAFSCFGTLLMWTVVVVVNLKLWLESMYLSFWYIFTIIISILGFVVTTVIYN 1268
            .:.|..|...||......|||::...:|..|.|||.|::.|.::.....|..|:..:|:.::.:.
 Frog   974 LFQNPALEGNGQVYGNWSFGTMVFTILVFTVTLKLALDTRYWTWMNHLAIWGSLAFYVIFSLFWG 1038

  Fly  1269 VINLDY--DTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQRALNIKS 1320
            .|...:  ...:|:.::::|.|:.:||.||:.....|.|:..:.:::   |:|:
 Frog  1039 GIIWPFLKQQRMYFVFSHILTSVSIWLGIILLIFVSLYPEIVLILVK---NLKT 1089

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	Haloacid Dehalogenase-like Hydrolases	74..1317	CDD:473868	421/1287 (33%)
atp11c	XP_004917005.2	P-type_ATPase_APLT_Dnf-like	42..971	CDD:319770	393/1170 (34%)
		7TMR-DISM_7TM	954..>1071	CDD:429600	31/117 (26%)