Protein Alignment CG4301 and atp9b

DIOPT Version :10

• Sequence 1: NP_573125.1
• Gene: CG4301 / 32610
• FlyBaseID: FBgn0030747
• Length: 1342
• Species: Drosophila melanogaster
• Sequence 2: XP_002936489.3
• Gene: atp9b / 100497381
• XenbaseID: XB-GENE-1012387
• Length: 1256
• Species: Xenopus tropicalis
• Alignment Length: 1292
• Identity: 360/1292 - (27%)
• Similarity: 563/1292 - (43%)
• Gaps: 289/1292 - (22%)

  Fly    54 WLQIQIGGPQDIKKKRPKGQNRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVS 118
            ||    |.|:..::|.|:  |.||:.||.:.||:|..|.:||:...|.||||:.....:....:.
 Frog   227 WL----GCPEKCEEKYPR--NAIKNQKYNIFTFIPGVLYQQFKFFLNLYFLVVACSQFVSALKIG 285

  Fly   119 PM-TSLLPLVFVIAVTAAKQGYEDILRYRTDNVVNSSPVTVIRDGKEAIIKSQDVIPGELIVVER 182
            .: |...||.||:|||..::..::..|::.|..:||...:.:....:..:||.|:..|:||:||:
 Frog   286 YLYTYWAPLGFVLAVTMVREAADEYRRFQRDKEMNSQLYSKLTIRGKVQVKSSDIQVGDLIIVEK 350

  Fly   183 DCDVPCDLVLLRSTDPHGKCFITTANLDGESNLK---TLMVPRDLPTV-DLPEMHKLGIIECESP 243
            :..:|.|:|.||:::..|.|||.|..||||::.|   .:...:.||.: ||..::  ..:..:.|
 Frog   351 NQRIPADMVFLRTSEKTGSCFIRTDQLDGETDWKLKIAVSCTQRLPALGDLFSIN--AYVYAQKP 413

  Fly   244 TTDLYSFNGKIELKGGEGRV-LPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNK 307
            ..|::||.|....:..:..: ..||.||.|. .|.|..:..|||..:|||..::..:|:...:||
 Frog   414 QLDIHSFEGNFTREDTDPSIHESLSIENTLW-ASTVVASGTVIGVVIYTGKETRSVMNTSNPKNK 477

  Fly   308 NASSETYINRFLIVILVALIAIVTLLYFLKRYNELFVIPKLTYLGDATDSYSVKQFLQDYLSFLI 372
            ....:..:|:....:.:||:|:..::..|:.    ||.|...||                ..||:
 Frog   478 VGMLDLELNQLTKALFLALVALSVVMVTLQG----FVGPWYRYL----------------FRFLL 522

  Fly   373 LFNYLIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTL 437
            ||:|:|||||.|.:::.:....|.      :..:|.....||.||.:.||||::..|.:||||||
 Frog   523 LFSYIIPISLRVNLDMGKAAYGWM------IMRDENIPGTVVRTSTIPEELGRLVYLLTDKTGTL 581

  Fly   438 TKNEMNFQQCSINGNKFLFKKTRLEDEETKALLDINKFSANQRVFFQALSICHTVQVASGSLEQA 502
            |:|||            :||:..|                            .||...:.::::.
 Frog   582 TQNEM------------VFKRLHL----------------------------GTVSYGTDTMDEI 606

  Fly   503 DAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIISSDV 567
                                        ::|.||..|.:....:.:|:.||.|:
 Frog   607 ----------------------------QNHIASSYSLVQPSQSCNNNTSATPS----------- 632

  Fly   568 NPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTT---NFR 629
                          ||                   |.:|...:.:|..:.|...|:...   |..
 Frog   633 --------------RK-------------------GQSSAPKVRKTVSSRVHEAVKAIALCHNVT 664

  Fly   630 PISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSR 694
            |:                :|:.:|
 Frog   665 PV----------------YESRAG----------------------------------------- 672

  Fly   695 ESYAAPTFTRQPTILVRAESQRRKNEIRDFI-FTLDYQASSPDEKALVEACANLGMVYTGDDDET 758
                           |..|::..:.: :||. ....||||||||.|||:...::|:.....|..:
 Frog   673 ---------------VNGETEYSEVD-QDFCDENRTYQASSPDEVALVQWTESVGLTLVNRDLTS 721

  Fly   759 LRVRIVPPHMDYKRPFAKPREETFQRLHVLEFTSDRKRMSVIVR-DTDGKKWIYTKGAESYVFPL 822
                     |..|.|..:..  ||..|.:..|||:.|||.:||| ::.|....|.|||:.
 Frog   722 ---------MQLKTPGGQIL--TFCILQIFPFTSESKRMGIIVREESSGDITFYMKGADV----- 770

  Fly   823 CANSSAELVTKT---DAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEE 884
               :.|.:|...   |....:.||.|||||.:|::.:|||:||||.....||..|:.:|......
 Frog   771 ---AMATIVQYNDWLDEECGNMAREGLRTLVVAKKSLSEEQYQDFENRYNQAKLSMHDRALKVAA 832

  Fly   885 CYAKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAK 949
            ....:|..::||..|.|||.||.||..||..|:.||||||:|||||:|||..||.|...:..:..
 Frog   833 VVESLEREMELLCLTGVEDQLQTDVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRNQD 897

  Fly   950 KYFIMECKNREEMLLHLNALDREIIFGIGQECALLIDGKSLGVALAEASSEFRDVAVKCTAVLCC 1014
            .:......||.|..|.|||..|:      .:|||:|.|.||.|.|.....||.::|.:|.||:||
 Frog   898 IHIFRPVSNRSEAHLELNAFRRK------HDCALVIAGDSLEVCLKYYEHEFVELACQCPAVVCC 956

  Fly  1015 RLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMIQEAHVGIGIMGREGRQAARCADFAFAKFC 1079
            |.||.||:.:|.|:: .:....|.:||||.|||||||.|..||||.|:||:||:..|||:..:|.
 Frog   957 RCSPTQKAHIVKLLQ-QHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFK 1020

  Fly  1080 MLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMFLFQFHTLFSSSSVYDSLFLTLYNVIYTSL 1144
            .:.|||:|||.....|.:.|..:..::.:|...:..:|.....|:|..:|....:..|..|||..
 Frog  1021 HIGRLLMVHGRNSYKRSAALGQFVIHRGLVISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMF 1085

  Fly  1145 PILFIAISE--KPYTEEKLMRTPQLYKKNTDNKQLHWPYFLMWVLFAIYHSVIIFYFAFCFFYYN 1207
            |:..:.:.:  ||   |..:..|:|||..|..:.|.:..||:|||.:||...|:.:.|...|...
 Frog  1086 PVFSLVLDQDVKP---ETALLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMFGALVLFESE 1147

  Fly  1208 NVLLNYGQTVAFSCFGTLLMWTVVVVVNLKLWLESMYLSFW-YIFTIIISILGFVVTTVIYNV-- 1269
            .|     ..||.|....:|...::|.:.::.|       .| .:...:.|:..:|.:....|.
 Frog  1148 FV-----HVVAISFTALILTELLMVALTIRTW-------HWLMVVAELFSLASYVASLAFLNEYF 1200

  Fly  1270 ----INLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDYTIRMLQRALNIKSFS 1322
                ::|....|.  |:...|..|  |..:.:|.|:|| |.|.::.|:|..:..|:|
 Frog  1201 GLGRVSLGAFLDA--AFITTLTFL--WKVLAITVVSCL-PLYILKYLKRKFSPPSYS 1252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	Haloacid Dehalogenase-like Hydrolases	74..1317	CDD:473868	352/1265 (28%)
atp9b	XP_002936489.3	P-type_ATPase_APLT_Neo1-like	240..1165	CDD:319841	332/1174 (28%)
		Cation_ATPase	658..769	CDD:463817	40/194 (21%)