Protein Alignment CG4301 and atp11a

DIOPT Version :9

• Sequence 1: NP_573125.1
• Gene: CG4301 / 32610
• FlyBaseID: FBgn0030747
• Length: 1342
• Species: Drosophila melanogaster
• Sequence 2: XP_031752894.1
• Gene: atp11a / 100485769
• XenbaseID: XB-GENE-1010941
• Length: 1193
• Species: Xenopus tropicalis
• Alignment Length: 1402
• Identity: 465/1402 - (33%)
• Similarity: 689/1402 - (49%)
• Gaps: 354/1402 - (25%)

  Fly    10 SGFRR-IDRLGAHRQTPWADQESFHLKDAFLWNWHKGSRVSTINDWLQIQIGGPQDIKKKRPKGQ 73
            |..|| |:|..|..:. |.|..:.::       .||           |...|....|.::.|  .
 Frog     4 SALRRLINRYCAGEEN-WVDNRTIYV-------GHK-----------QPPPGTEAYIPQRYP--D 47

  Fly    74 NRIKSTKYTLITFLPQNLLEQFRRIANFYFLVMTIISLLIDSPVSPMTSLLPLVFVIAVTAAKQG 138
            |||.|:|||...|:|:||.||||||||||||::.::.|:||:|.||:||.|||.|||.|||.|||
 Frog    48 NRIVSSKYTFWNFVPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQG 112

  Fly   139 YEDILRYRTDNVVNSSPVTVIRDGKEAIIKSQDVIPGELIVVERDCDVPCDLVLLRSTDPHGKCF 203
            |||.||::.||.:|...|.|::.||....:|:.:..|::::|..|...|||||.|.|:...|.||
 Frog   113 YEDWLRHKADNAMNQYSVHVVQHGKLVRTQSRKLRVGDIVMVREDEAFPCDLVFLSSSREDGTCF 177

  Fly   204 ITTANLDGESNLKTLMVPRDLPTV----DLPEMHKLGIIECESPTTDLYSFNGKIEL--KGGEGR 262
            :|||:|||||:.||.....|..:.    ::..:|  ..||||.|..|||.|.|:|.:  :..|..
 Frog   178 VTTASLDGESSHKTYYAINDTKSFHHEEEMEGLH--ATIECEQPQPDLYKFVGRINIYNEADEPV 240

  Fly   263 VLPLSTENVLLRGSRVKNTECVIGCAVYTGMISKLQLNSRLTRNKNASSETYINRFLIVILVALI 327
            ..||.:||:||||:.:||||.:.|.|:||||.:|:.||.:....|.::.|..:|.||||.|..||
 Frog   241 ARPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILI 305

  Fly   328 A---IVTLLYFLKR---------YNELFVIPKLTYLGDATDSYSVK-QFL---QDYLSFLILFNY 376
            :   |.|:|.::.:         ||:            .|||...| :||   .|:|:|::||||
 Frog   306 SKALINTVLKYIWQSDSSRDEPWYNQ------------KTDSERQKNKFLGAFTDFLAFMVLFNY 358

  Fly   377 LIPISLYVTIELQRVIGSWFMEWDLELYENETDQPCVVNTSNLNEELGQINILFSDKTGTLTKNE 441
            :||:|:|||:|:|:.:||:|:.||.|:::..|.:..:||||:|||||||:..:|:|||||||:|.
 Frog   359 IIPVSMYVTVEMQKFLGSYFISWDEEMFDETTGEGPIVNTSDLNEELGQVEYIFTDKTGTLTENN 423

  Fly   442 MNFQQCSINGNKF----LFKKTRLEDEETKALLDINKFSA---NQRVFFQALSICHTVQVASGSL 499
            |.|.:|.|.|:.:    :.....|.|.....::|.:..:.   .:.:||:||.:||||||
 Frog   424 MEFVECCIEGHVYIPHVICNGQILPDCMGIDMIDSSPGAGGKEREELFFRALCLCHTVQV----- 483

  Fly   500 EQADAGTAKREPVTAIKSGPPEMYSISDITEESHNASQQSELNVGHTIDNSVSAHPNGVNSTIIS 564
                                         .:|.|             ||
 Frog   484 -----------------------------KDEDH-------------ID---------------- 490

  Fly   565 SDVNPLLVSDDGYGVERRKRPVVIKRSPNFARSNRMNNGAASDLNINQTDPNTVTNGVEPTTNFR 629
                                                                             
 Frog   491 ----------------------------------------------------------------- 490

  Fly   630 PISLQFRRSTSEKDLQQSWEAPSGQAPGHRRAHSYGAPNAYLTNPVTASTPPAGVLFRSPSTTSR 694
                                       |.:::...|..:.|:
 Frog   491 ---------------------------GEKKSSHSGRSSVYI----------------------- 505

  Fly   695 ESYAAPTFTRQPTILVRAESQRRKNEIRDFIFTLDYQASSPDEKALVEACANLGMVYTGDDDETL 759
                                                 :|||||.||||....||..:
 Frog   506 -------------------------------------SSSPDEVALVEGVQRLGYTF-------- 525

  Fly   760 RVRIVPPHMDYKRPFAKPRE---ETFQRLHVLEFTSDRKRMSVIVRDTDGKKWIYTKGAESYVFP 821
             :|:...:|:...     ||   |.|:.|.||.|.|.|:|||||||.:.|..:::.|||:|.:||
 Frog   526 -LRVKDNYMEICN-----RENDIEKFELLQVLTFDSVRRRMSVIVRSSTGDIYLFCKGADSSIFP 584

  Fly   822 LCANSSAELVTKTDAHISDFARLGLRTLAIARRLISEEEYQDFLVELAQANSSLENRKQLSEECY 886
            .......:.:.   |.:...|..|||||.:|.:..|::||:.....|..|..:|::|::...|.|
 Frog   585 RVREGKVDQIR---ARVERNAVEGLRTLCVAYKKFSQDEYEWANKLLKDAQLALQDREKKLAEAY 646

  Fly   887 AKIESNLDLLGATAVEDALQDDVADTLVSLQAAGIKIWVLTGDKVETALNIALSCGHIPPDAKKY 951
            .:||.:|.|||||||||.||:..|||:.|||.||||:|||||||:|||.....:|        |.
 Frog   647 EQIEQDLILLGATAVEDRLQEKAADTIESLQKAGIKVWVLTGDKMETASATCYAC--------KL 703

  Fly   952 F-----IME--CKNREE-------------MLLHLNALDREIIFGIG---QECALLIDGKSLGVA 993
            |     ::|  .|..||             :|.|..:|.|:...|..   |:..|:|||.:|.:.
 Frog   704 FRRNTQLLELTTKRIEEQSLHDVLFELSRTVLRHSESLTRDNFSGFSTDFQDYGLIIDGATLSLI 768

  Fly   994 LAE----ASSEFRDVAVK----CTAVLCCRLSPLQKSEVVSLIKSSNENYNTASIGDGANDVSMI 1050
            :..    :|:.:|:|.::    |:||||||::||||:::|.|||||.|:..|.::||||||||||
 Frog   769 MKPREDGSSTNYREVFLEICRNCSAVLCCRMAPLQKAQIVKLIKSSREHPITLAVGDGANDVSMI 833

  Fly  1051 QEAHVGIGIMGREGRQAARCADFAFAKFCMLKRLLLVHGHYHSVRLSLLVLYFFYKNIVFMGIMF 1115
            .|||||||::|:|||||||.:|:|..||..|||:||:||||:.||:|.||.||||||:.|:...|
 Frog   834 LEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKRMLLIHGHYYYVRISELVQYFFYKNVCFIFPQF 898

  Fly  1116 LFQFHTLFSSSSVYDSLFLTLYNVIYTSLPILFIAISEKPYTEEKLMRTPQLYKKNTDNKQLHWP 1180
            |:||...||...:||:.:|||||:.:||||||..::.|:..:.:.|.|.|.||:....|..|.|.
 Frog   899 LYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLIEQHVSVDVLKRDPTLYRDIAKNALLRWR 963

  Fly  1181 YFLMWVLFAIYHSVIIFYFAFCFFYYNNVLLNYGQTVAFSCFGTLLMWTVVVVVNLKLWLESMYL 1245
            .|:.|....::.:.:.|:.|: |.|.|..:.:.||.:....||||:...:|..|..||.|::.|.
 Frog   964 LFIYWTFLGLFDAAVFFFGAY-FLYDNATVTSNGQMLGNWTFGTLVFTVLVFTVTFKLALDTHYW 1027

  Fly  1246 SFWYIFTIIISILGFVVTTVIYNVI---NLDYDTDIYWAYNNLLASLPVWLWIIVTCVACLVPDY 1307
            ::...|.|..|:|.:::.::::..|   .|:|.. :|:.:..:|:|.|.||.|::..:..|:||.
 Frog  1028 TWINHFVIWGSLLFYIIFSLLWGGIIWPFLNYQR-MYYVFIQMLSSGPAWLGIVLLIIVSLLPDV 1091

  Fly  1308 TIRMLQRALNIKSFSIFPGKQRKLK---MREKFESTY 1341
            ..:::.|.|       :|....:::   ||.|..|.:
 Frog  1092 LRKVICRQL-------WPTATERIQDASMRSKEVSEF 1121

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4301	NP_573125.1	PhoLip_ATPase_N	57..121	CDD:292826	32/63 (51%)
		ATPase-Plipid	74..1317	CDD:273734	445/1308 (34%)
		E1-E2_ATPase	127..>345	CDD:278548	95/235 (40%)
		Cation_ATPase	<734..823	CDD:289987	36/91 (40%)
		HAD_like	<1036..1066	CDD:304363	21/29 (72%)
		PhoLip_ATPase_C	1068..1317	CDD:292829	92/251 (37%)
atp11a	XP_031752894.1	P-type_ATPase_APLT_Dnf-like	47..983	CDD:319770	411/1189 (35%)
		RDD	<965..1061	CDD:412544	26/96 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3680
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	795	1.000	Inparanoid score	I498
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185990at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24092
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X848
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.160