Protein Alignment CG9981 and DNF1

DIOPT Version :9

• Sequence 1: NP_001259610.1
• Gene: CG9981 / 32609
• FlyBaseID: FBgn0030746
• Length: 1060
• Species: Drosophila melanogaster
• Sequence 2: NP_011093.3
• Gene: DNF1 / 856913
• SGDID: S000000968
• Length: 1571
• Species: Saccharomyces cerevisiae
• Alignment Length: 1263
• Identity: 352/1263 - (27%)
• Similarity: 587/1263 - (46%)
• Gaps: 272/1263 - (21%)

  Fly    24 QKPLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIV-SFFVNETISPLVSLLPLLFVMIIT 87
            |.|.|::.|||||..||||.|...||......|||::.|: :|.:....:|.:|.:||:.::|||
Yeast   190 QYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIIT 254

  Fly    88 ALKEGLEDYSRSKSDKLVNTARVTVIRNGKEEIINS------------------QFI-------- 126
            |:|:.:||..|:..|..||..:..::...:.|.:::                  :||
Yeast   255 AIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWRRFKKANSRLLFKFIQYCKEHLT 319

  Fly   127 ----------------------------------------------------------------- 126
                                                                             
Yeast   320 EEGKKKRMQRKRHELRVQKTVGTSGPRSSLDSIDSYRVSADYGRPSLDYDNLEQGAGEANIVDRS 384

  Fly   127 VP-----------------GDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNLKT--- 171
            :|                 ||:|.:.|:.::|.|::||.:|..|..|:|.|.|||||||||.
Yeast   385 LPPRTDCKFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQS 449

  Fly   172 -ICVPTNYLLAGDHELQGKDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLR 235
             .|  ||.:.......:.|..|..|...::|||:.|.::.|:..||...:.    |:||:|:|||
Yeast   450 LKC--TNTIRTSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNE----PITINNVLLR 508

  Fly   236 GVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMVALIVGMIVVVVVLYL---- 296
            |..:::|:..:|..::||..||:.|||..|..|.:...:.:|   .::::..:::.::.::
Yeast   509 GCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELN---FSVVINFVLLFILCFVSGIA 570

  Fly   297 --IERHKEAKIVPTMPYQGPPTNFNSAWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMH 359
              :...|:.:  ....|:......::|...|..|...::|:..:||||.|:::|:.:.....|::
Yeast   571 NGVYYDKKGR--SRFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIY 633

  Fly   360 NDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNY--------- 415
            .|:.||:.:.|.||...:.|::::||||..:|||||||||:|:|:|..|.:.|.:|
Yeast   634 GDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALA 698

  Fly   416 ---QLQNTHLVSEGTDEKFELEKLDADAAV----------------------------------- 442
               :.|...:.:||..||.|:.| |.|..:
Yeast   699 GLRKRQGIDVETEGRREKAEIAK-DRDTMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASGEV 762

  Fly   443 -------LFEALAVCHTVEVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCA 500
                   ...|||:||:|.|         |::....::..|         :|.||||.||:....
Yeast   763 QQRCCEHFMLALALCHSVLV---------EANPDNPKKLDL---------KAQSPDEAALVATAR 809

  Fly   501 SLGLVYEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIVR-------DQSDTIWLYSK 558
            .:|..:.|:....| |......:| :|:.|::|||:|.|:|||.||:       |:...: |..|
Yeast   810 DVGFSFVGKTKKGL-IIEMQGIQK-EFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRAL-LICK 871

  Fly   559 GAESAIFPR------CKASPLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQ 617
            ||:|.|:.|      ..:..::|:|...:.:||..||||:.:.:|.|:..|...:.|.|..|...
Yeast   872 GADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAAS 936

  Fly   618 LSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGL 682
            |:||.:.:....:::|.||.|||.||:||.||:.|.:.:|.|..||:|:|||||||||||.|||.
Yeast   937 LANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGF 1001

  Fly   683 ACRHIPRGSKQHFIINTT---------EPAELLARL---------DMIGDDE-----------PE 718
            :| ::.....:..:|.||         ||:|::..|         ::.|.:|           |:
Yeast  1002 SC-NLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLSKYLKEYFNLTGSEEEIFEAKKDHEFPK 1065

  Fly   719 ---VLIVDGTTITALL--EHTPRQFADLALRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGD 778
               .:::||..:...|  |...|:|..|...||||||||:||.||:.:|.|:|.....:|.||||
Yeast  1066 GNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGD 1130

  Fly   779 GANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKN 843
            |:|||:|||.|.:||||.|.||:||..|:|::|.:|..|.||.||||.::.:|||.::..:.|||
Yeast  1131 GSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKN 1195

  Fly   844 IIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLA 908
            :|....:..|.:|:.:..:.:|...|:..:::.:.|.....|.|.|:|.::...|..|:||:...
Yeast  1196 MIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGI 1260

  Fly   909 HNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFNGGQTASFQTF-GTMLITIIVIVGNL 972
            ..::.:...|..::|:|..|..|.|||.|.:.:...::.:.|.....:.| |..:.||.||..|.
Yeast  1261 LRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNT 1325

  Fly   973 KLLLVAHYMTYRNFA---MILASIAAFMLTTYLYNLYTSGELYDVYNQFLSSLPIWLFTIICSVA 1034
            .:||  |...:..|:   :.|:.:..|..|....:...|.|.:....:...:...|....:..:.
Yeast  1326 YVLL--HQYRWDWFSGLFIALSCLVVFAWTGIWSSAIASREFFKAAARIYGAPSFWAVFFVAVLF 1388

  Fly  1035 CLLPDFV------------IKVVNDMYR 1050
            ||||.|.            :::|.:|::
Yeast  1389 CLLPRFTYDSFQKFFYPTDVEIVREMWQ 1416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	19/42 (45%)
		ATPase-Plipid	28..1051	CDD:273734	350/1259 (28%)
		E1-E2_ATPase	84..>189	CDD:278548	40/216 (19%)
		Cation_ATPase	<489..568	CDD:289987	31/91 (34%)
		HAD_like	<758..807	CDD:304363	26/48 (54%)
		PhoLip_ATPase_C	804..1050	CDD:292829	65/261 (25%)
DNF1	NP_011093.3	ATPase-Plipid	191..1413	CDD:273734	350/1257 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710