Protein Alignment CG9981 and DNF2

DIOPT Version :9

• Sequence 1: NP_001259610.1
• Gene: CG9981 / 32609
• FlyBaseID: FBgn0030746
• Length: 1060
• Species: Drosophila melanogaster
• Sequence 2: NP_010378.1
• Gene: DNF2 / 851667
• SGDID: S000002500
• Length: 1612
• Species: Saccharomyces cerevisiae
• Alignment Length: 1259
• Identity: 350/1259 - (27%)
• Similarity: 568/1259 - (45%)
• Gaps: 275/1259 - (21%)

  Fly    26 PLNRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIV-SFFVNETISPLVSLLPLLFVMIITAL 89
            |.|::.|||||..||.|.|...||......||||:.|: :|.:....:|..:.:||:.::||||:
Yeast   230 PRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAI 294

  Fly    90 KEGLEDYSRSKSDKLVNTARVTVIRNGKEEII--------------------------------- 121
            |:|:||..|:..|..||..|..::...|.|.:
Yeast   295 KDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWRRFKKANTRALIKIFEYFSENLTAA 359

  Fly   122 -----------------NSQFIVP----------------------------------------- 128
                             ||:...|
Yeast   360 GREKKLQKKREELRRKRNSRSFGPRGSLDSIGSYRMSADFGRPSLDYENLNQTMSQANRYNDGEN 424

  Fly   129 ------------------------GDLVVVRNDGDVPCDLVLLQSSSADRKCFVNTANLDGETNL 169
                                    ||:|.|.|:.::|.|::||.:|..|..|:|.|.||||||||
Yeast   425 LVDRTLQPNPECRFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNL 489

  Fly   170 KT-ICVPTNYLLAGDHEL-QGKDCIVCEPSSADLYTFNGRLELRSGNDGAGSSAGDALPLTIDNL 232
            |. ..:..:.::....:: :.|..:..|...|:||::.|..:.:...:|...:.    |:.|:||
Yeast   490 KVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNGNIRNE----PVNINNL 550

  Fly   233 LLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYTGNKSASSEKYINRFMVALIVGMIVVVVVLYLI 297
            ||||..:::|:..:|..|:||..||:.:|:..|..|.:...:.:|   .::|:..:::.::.:
Yeast   551 LLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELN---FSVILNFVLLFILCF-- 610

  Fly   298 ERHKEAKIVPTMPYQGPPTNFNSAWQIFE-----------DFLSF---LLLFNYMVPISAYMNIE 348
                .|.||..:.|:..|.:.:    .||           .|:||   ::|:..:||||.|:::|
Yeast   611 ----TAGIVNGVYYKQKPRSRD----YFEFGTIGGSASTNGFVSFWVAVILYQSLVPISLYISVE 667

  Fly   349 VYRIFGMHFMHNDLHLYDEETDQPCRVNASNLNEELGQVNILFSDKTGTLTKNLMKFVNCYVPGT 413
            :.:.....|::.|:.||:.:.|.||...:.|::::|||:..:|||||||||:|:|:|..|.:.|.
Yeast   668 IIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGV 732

  Fly   414 NY------------QLQNTHLVSEGTDEKFELEKLDADAAV------------------------ 442
            :|            :.|...:.|||..||.|:.| |.:..:
Yeast   733 SYGRAYTEALAGLRKRQGVDVESEGRREKEEIAK-DRETMIDELRSMSDNTQFCPEDLTFVSKEI 796

  Fly   443 ------------------LFEALAVCHTVEVLQEVGD-KTLESSESVSEQSHLMSRNIVDRYQAS 488
                              ...|||:||:|.|.....| |.|:                   .:|.
Yeast   797 VEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPKKLD-------------------IKAQ 842

  Fly   489 SPDEKALLEGCASLGLVYEGQENDVLSICRYPSAEKVQFKRLHVLEFSSERQRMSVIVRDQSDT- 552
            ||||.||:.....||..:.|.....| |......:| :|:.|:||||:|.|:|||.|::....|
Yeast   843 SPDESALVSTARQLGYSFVGSSKSGL-IVEIQGVQK-EFQVLNVLEFNSSRKRMSCIIKIPGSTP 905

  Fly   553 -----IWLYSKGAESAIFPRC----KASPLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFE 608
                 ..|..|||:|.|:.|.    ..:.|:|:|...:.:||..||||:.:.:|.||..|...:.
Yeast   906 KDEPKALLICKGADSVIYSRLDRTQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWV 970

  Fly   609 ELYRKANTQLSNRNELIASCYETVENELDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDK 673
            :.|..|...::||.|.:....:.:|.||.|||.||:||.||:.|.:::..|..||:|:|||||||
Yeast   971 KTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDK 1035

  Fly   674 VETAYNIGLACRHIPR-----------------GSKQHFIINTTEPAELLARLDMIGDDE----- 716
            ||||.|||.:|..:..                 ||....::|......|..:..|.|.:|
Yeast  1036 VETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKFGMSGSEEELKEA 1100

  Fly   717 ------PE---VLIVDGTTITALL--EHTPRQFADLALRCRAVLCCRLSPLQKSEIVTLIKRRKK 770
                  |:   .:|:||..:...|  |...|:|..|...|:||||||:||.||:.:|.|:|:...
Yeast  1101 KREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLD 1165

  Fly   771 YITAAIGDGANDVSMIQEAHIGIGITGREGKQAARCADFSIARFEMLRRLFLVHGHYNSQRLAFL 835
            .:|.|||||:|||:|||.|.:|:||.|.||:||..|:|::|.:|..:.||.||||.:..:|||.:
Yeast  1166 VMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEM 1230

  Fly   836 VLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLWLFDIVYISFSFTVLAICDKDYSEETLLSH 900
            :..:.|||:|.|..:..|.:|:.:..:.::...||..:::.:.|....:||:.|:|.|:...:..
Yeast  1231 IPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLV 1295

  Fly   901 PELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFTYAMLNDANVLFNGGQTASFQTFGTMLITI 965
            |:||:.....::.:...|..::|:|..|..|.|||.|...:...|:...|.....:.|..:.:|.
Yeast  1296 PQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTA 1360

  Fly   966 IVIVG-NLKLLLVAHYMTYRNFAMILASIAAFMLTTYLY-NLYTSGELYDVYNQFLSSLPIWLFT 1028
            |.:.. |..:.:..:...:.....|..|:|.|...|.:: :..:|.|.|....:..:....|...
Yeast  1361 IAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFYGWTGIWTSSSSSNEFYKGAARVFAQPAYWAVL 1425

  Fly  1029 IICSVACLLPDFVIKVVNDMYRKV 1052
            .:..:.||||.|.|    |..||:
Yeast  1426 FVGVLFCLLPRFTI----DCIRKI 1445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	18/40 (45%)
		ATPase-Plipid	28..1051	CDD:273734	347/1254 (28%)
		E1-E2_ATPase	84..>189	CDD:278548	41/221 (19%)
		Cation_ATPase	<489..568	CDD:289987	31/84 (37%)
		HAD_like	<758..807	CDD:304363	25/48 (52%)
		PhoLip_ATPase_C	804..1050	CDD:292829	62/247 (25%)
DNF2	NP_010378.1	ATPase-Plipid	229..1456	CDD:273734	350/1259 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710