DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9981 and AT1G72700

DIOPT Version :9

Sequence 1:	NP_001259610.1	Gene:	CG9981 / 32609	FlyBaseID:	FBgn0030746	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	NP_001322799.1	Gene:	AT1G72700 / 843602	AraportID:	AT1G72700	Length:	1228	Species:	Arabidopsis thaliana

Alignment Length:	1146	Identity:	382/1146 - (33%)
Similarity:	575/1146 - (50%)	Gaps:	185/1146 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QQKPL----NRVTTTKYTWFTFLPLNFYEQFRRAVYFYFLIITIVSFFVNETISPLVSLLPLLFV 83
            ::|||    |.|:||:|...||.|.:.||||.||...|||:..|:|.|.....:....:.||:||
plant    52 KKKPLRYRSNYVSTTRYNLITFFPKSLYEQFHRAANLYFLVAAILSVFPLSPFNKWSMIAPLVFV 116

  Fly    84 MIITALKEGLEDYSRSKSDKLVNTARVT-------VIRNGKEEIINSQFIVPGDLVVVRNDGDVP 141
            :.::.|||.|||:.|...|..:| ||.|       |.|..|.:.::     .||:|.|..|...|
plant   117 VGLSMLKEALEDWRRFMQDVKIN-ARKTCVHKSDGVFRQRKWKKVS-----VGDIVKVEKDEFFP 175

  Fly   142 CDLVLLQSSSADRKCFVNTANLDGETNLKT-----ICVPTNYLLAGDHELQG-KDCIVCEPSSAD 200
            .||:||.||..|..|:|.|.|||||||||.     :.:|    |..|...:. ...|.||..:.:
plant   176 ADLLLLSSSYEDGICYVETMNLDGETNLKVKRSLEVSLP----LDDDESFKNFMATIRCEDPNPN 236

  Fly   201 LYTFNGRLELRSGNDGAGSSAGDALPLTIDNLLLRGVRVKSTERVVGCAIYTGMHTKLQLNSRYT 265
            ||||.|.||...          ...||....:|||..::::|..|.|..::||..||:..||
plant   237 LYTFVGNLEFER----------QTFPLDPSQILLRDSKLRNTTYVYGVVVFTGFDTKVMQNS--- 288

  Fly   266 GNKSASSEKYINRFMVALIVGMIVVVVVLYLI---------ERHKEAKIVPTMPY--QGPPTNF- 318
             .||.|....|.|.|..:|..::|:::::..|         |.|     :|.|.|  .|.|.:|
plant   289 -TKSPSKRSRIERTMDYIIYTLLVLLILISCISSSGFAWETEFH-----MPKMWYLRPGEPIDFT 347

  Fly   319 ---NSAWQIFEDFLSFLLLFNYMVPISAYMNIEVYRIFGMHFMHNDLHLYDEETDQPCRVNASNL 380
               |..:......::.|||:.|::|||.|::|||.:::...|::.|||:||:|:..|.....|||
plant   348 NPINPIYAGVVHLITALLLYGYLIPISLYVSIEVVKVWQASFINQDLHMYDDESGVPANARTSNL 412

  Fly   381 NEELGQVNILFSDKTGTLTKNLMKFVNCYVPGTNYQLQNTHL-----------------VSE--- 425
            |||||||:.:.||||||||.|.|.|:.|.:.||:|.::::.:                 :|.
plant   413 NEELGQVHTILSDKTGTLTCNQMDFLKCSIAGTSYGVRSSEVEVAAAKQMAVDLEEHGEISSTPQ 477

  Fly   426 ------GTDEKFELEKLDA-----------------------------------DAAVLFEALAV 449
                  ||.:....::::.                                   |....|..||:
plant   478 SQTKVYGTWDSSRTQEIEVEGDNNYNTPRAPIKGFGFEDNRLMNGNWLRESQPNDILQFFRILAI 542

  Fly   450 CHTV--EVLQEVGDKTLESSESVSEQSHLMSRNIVDRYQASSPDEKALLEGCASLGL-VYEGQEN 511
            |||.  |:.:|.|..|                     |:|.||||.:.|......|. .::..::
plant   543 CHTAIPELNEETGKYT---------------------YEAESPDEASFLAAAREFGFEFFKRTQS 586

  Fly   512 DVLSICRYPSAEKV---QFKRLHVLEFSSERQRMSVIVRDQSDTIWLYSKGAESAIFPRC--KAS 571
            .|....|:..:.::   ::|.|::|||:|:|:||:|||||:...|.|..|||:|.||.|.  ...
plant   587 SVFIRERFSGSGQIIEREYKVLNLLEFTSKRKRMTVIVRDEEGQILLLCKGADSIIFERLAKNGK 651

  Fly   572 PLVEQTDAQITKYAQNGLRTMAVGRRMLTDDELFHFEELYRKANTQL-SNRNELIASCYETVENE 635
            ..:..|...:|:|.:.||||:|:..|.|.:||...:...:.||.|.: |:|:||:.:..:.:|.|
plant   652 TYLGPTTRHLTEYGEAGLRTLALAYRKLDEDEYAAWNSEFLKAKTSIGSDRDELLETGADMIEKE 716

  Fly   636 LDLLGATALEDALQEHVGETLEALQAAGLKIWVLTGDKVETAYNIGLACRHIPRGSKQ------- 693
            |.|:||||:||.||:.|.:.::.|..||||:|||||||:|||.|||.||..:.:|.:|
plant   717 LILIGATAVEDKLQKGVPQCIDKLAQAGLKLWVLTGDKMETAINIGFACSLLRQGMRQICITSMN 781

  Fly   694 -------------HFIINTTEPAELLARLDMIGDDEPE---VLIVDGTTITALLEHTPR-QFADL 741
                         ..|:|....|..:.:|    :.:|.   .||:||.|:|..||...: ||..|
plant   782 SEGGSQDSKRVVKENILNQLTKAVQMVKL----EKDPHAAFALIIDGKTLTYALEDDMKYQFLAL 842

  Fly   742 ALRCRAVLCCRLSPLQKSEIVTLIKRRKKYITAAIGDGANDVSMIQEAHIGIGITGREGKQAARC 806
            |:.|.:|:|||:||.||:.:|.|:|......|.|||||||||.|||||.||:||:|.||.||...
plant   843 AVDCASVICCRVSPKQKALVVRLVKEGTGKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMA 907

  Fly   807 ADFSIARFEMLRRLFLVHGHYNSQRLAFLVLFYCYKNIIITGCMALYQVYDLYSATNVYNSIYLW 871
            :|||||:|..|.||.:||||:..:|:|.::.::.||||.....:..::.:..:|..:|||..||.
plant   908 SDFSIAQFRFLERLLVVHGHWCYKRIAQMICYFFYKNIAFGLTLFYFEAFTGFSGQSVYNDYYLL 972

  Fly   872 LFDIVYISFSFTVLAICDKDYSEETLLSHPELYKPLAHNRQASMGVFSLWILNGFVQCFIIFFFT 936
            ||::|..|.....|.:.::|.|.|..|..|.||:....|..........|:.||.....:|||..
plant   973 LFNVVLTSLPVIALGVFEQDVSSEICLQFPALYQQGTKNLFFDWSRILGWMCNGVYASLVIFFLN 1037

  Fly   937 YAMLNDANVLFNGGQTASFQTFGTMLITIIVIVGNLKLLLVAHYMTYRNFAMILASIAAFMLTTY 1001
            ..::. :....:.||||.....||.:.|.|:...|:::.|...:.|:....:|..||..:.|...
plant  1038 IGIIY-SQAFRDNGQTADMDAVGTTMFTCIIWAANVQIALTMSHFTWIQHVLIWGSIGMWYLFVA 1101

  Fly  1002 LYNLYT---SGELYDVYNQFLSSLPI-WLFTIICSVACLLP 1038
            :|::..   ||.:|.:.::.|:..|| |:.|::.:||.:||
plant  1102 IYSMMPPSYSGNIYRILDEILAPAPIYWMATLLVTVAAVLP 1142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9981	NP_001259610.1	PhoLip_ATPase_N	20..66	CDD:292826	22/46 (48%)
		ATPase-Plipid	28..1051	CDD:273734	379/1137 (33%)
		E1-E2_ATPase	84..>189	CDD:278548	43/117 (37%)
		Cation_ATPase	<489..568	CDD:289987	30/82 (37%)
		HAD_like	<758..807	CDD:304363	28/48 (58%)
		PhoLip_ATPase_C	804..1050	CDD:292829	72/239 (30%)
AT1G72700	NP_001322799.1	ATPase-Plipid	58..1163	CDD:273734	379/1140 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	1	1.100	-	-	O	PTHR24092
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820